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EAC Basal Cell Carcinoma
Nayela Keen, MD; Arnaud F. Bewley, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Basal cell carcinoma (BCCa)
              • Synonyms

                • a.k.a. "rodent ulcer"
              • Definitions

                • Cutaneous slow-growing tumor, the cells of which resemble basal cells of epidermis (outer skin layer)
                  • Tendency for local tissue invasion; metastases rare

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              • Reporting Tips

                                                Selected References

                                                1. Nakayama M et al: Basal cell carcinoma of the head and neck. J Skin Cancer. 2011:496910, 2011
                                                2. Fattah A et al: Big Bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinomata. J Plast Reconstr Aesthet Surg. 63(5):e433-41, 2010
                                                3. Kyrgidis A et al: Clinical, histological and demographic predictors for recurrence and second primary tumours of head and neck basal cell carcinoma. A 1062 patient-cohort study from a tertiary cancer referral hospital. Eur J Dermatol. 20(3):276-82, 2010
                                                4. McGuire JF et al: Nonmelanoma skin cancer of the head and neck I: histopathology and clinical behavior. Am J Otolaryngol. 30(2):121-33, 2009
                                                5. Morselli P et al: Evaluation of clinical prognostic factors in T1 N0 M0 head and neck basal cell carcinoma. J Craniofac Surg. 20(1):98-100, 2009
                                                6. Cohen PR et al: Basal cell carcinoma with mixed histology: a possible pathogenesis for recurrent skin cancer. Dermatol Surg. 32(4):542-51, 2006
                                                7. Lovatt TJ et al: Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors. J Am Acad Dermatol. 52(3 Pt 1):468-73, 2005
                                                8. Lovatt TJ et al: Associations between UVR exposure and basal cell carcinoma site and histology. Cancer Lett. 216(2):191-7, 2004
                                                9. Fosko SW et al: Positron emission tomography for basal cell carcinoma of the head and neck. Arch Dermatol. 139(9):1141-6, 2003
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Basal cell carcinoma (BCCa)
                                                            • Synonyms

                                                              • a.k.a. "rodent ulcer"
                                                            • Definitions

                                                              • Cutaneous slow-growing tumor, the cells of which resemble basal cells of epidermis (outer skin layer)
                                                                • Tendency for local tissue invasion; metastases rare

                                                            IMAGING

                                                            • General Features

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          • Image Interpretation Pearls

                                                                                            • Reporting Tips

                                                                                              Selected References

                                                                                              1. Nakayama M et al: Basal cell carcinoma of the head and neck. J Skin Cancer. 2011:496910, 2011
                                                                                              2. Fattah A et al: Big Bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinomata. J Plast Reconstr Aesthet Surg. 63(5):e433-41, 2010
                                                                                              3. Kyrgidis A et al: Clinical, histological and demographic predictors for recurrence and second primary tumours of head and neck basal cell carcinoma. A 1062 patient-cohort study from a tertiary cancer referral hospital. Eur J Dermatol. 20(3):276-82, 2010
                                                                                              4. McGuire JF et al: Nonmelanoma skin cancer of the head and neck I: histopathology and clinical behavior. Am J Otolaryngol. 30(2):121-33, 2009
                                                                                              5. Morselli P et al: Evaluation of clinical prognostic factors in T1 N0 M0 head and neck basal cell carcinoma. J Craniofac Surg. 20(1):98-100, 2009
                                                                                              6. Cohen PR et al: Basal cell carcinoma with mixed histology: a possible pathogenesis for recurrent skin cancer. Dermatol Surg. 32(4):542-51, 2006
                                                                                              7. Lovatt TJ et al: Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors. J Am Acad Dermatol. 52(3 Pt 1):468-73, 2005
                                                                                              8. Lovatt TJ et al: Associations between UVR exposure and basal cell carcinoma site and histology. Cancer Lett. 216(2):191-7, 2004
                                                                                              9. Fosko SW et al: Positron emission tomography for basal cell carcinoma of the head and neck. Arch Dermatol. 139(9):1141-6, 2003