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Ectopic Pancreatic Tissue
Siva P. Raman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Heterotopic pancreas; pancreatic rests; aberrant or accessory pancreas; pancreatic choristoma; pancreatic adenomyoma
          • Definitions

            • Pancreatic tissue located outside of normal confines of pancreas and lacking any anatomic, ductal, or vascular connection with main pancreas

          IMAGING

          • General Features

            • Fluoroscopic Findings

              • CT Findings

                • MR Findings

                  • Other Modality Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Shamoon D et al: A case of heterotopic pancreatic tissue discovered in the distal esophagus. Case Rep Gastrointest Med. 2020:4695184, 2020
                                    2. Wood CG et al: Pancreatitis in the developmentally anomalous pancreas. Abdom Radiol (NY). 45(5):1316-23, 2020
                                    3. Yoo J et al: Multiparametric MRI and 18F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions. Eur Radiol. 30(3):1634-43, 2020
                                    4. Seddon K et al: Gastric heterotopic pancreas in children: a prospective endoscopic study. J Pediatr Surg. 55(10):2154-58, 2019
                                    5. Rezvani M et al: Heterotopic pancreas: histopathologic features, imaging findings, and complications. Radiographics. 37(2):484-99, 2017
                                    6. Jang KM et al: Ectopic pancreas in upper gastrointestinal tract: MRI findings with emphasis on differentiation from submucosal tumor. Acta Radiol. 54(10):1107-16, 2013
                                    7. Kalaitzakis E et al: Gastric ectopic pancreas: not always an innocent bystander. JOP. 14(6):684-5, 2013
                                    8. O'Malley RB et al: Case of the season: ectopic pancreas. Semin Roentgenol. 48(3):188-91, 2013
                                    9. Hur BY et al: Gastroduodenal glomus tumors: differentiation from other subepithelial lesions based on dynamic contrast-enhanced CT findings. AJR Am J Roentgenol. 197(6):1351-9, 2011
                                    10. Wei R et al: Upper gastrointestinal tract heterotopic pancreas: findings from CT and endoscopic imaging with histopathologic correlation. Clin Imaging. 35(5):353-9, 2011
                                    11. Kim JY et al: Ectopic pancreas: CT findings with emphasis on differentiation from small gastrointestinal stromal tumor and leiomyoma. Radiology. 252(1):92-100, 2009
                                    12. Nijs EL et al: Congenital and developmental pancreatic anomalies: ultrasound, computed tomography, and magnetic resonance imaging features. Semin Ultrasound CT MR. 28(5):395-401, 2007
                                    13. Mortelé KJ et al: Multimodality imaging of pancreatic and biliary congenital anomalies. Radiographics. 26(3):715-31, 2006
                                    14. Yu J et al: Congenital anomalies and normal variants of the pancreaticobiliary tract and the pancreas in adults: part 2, Pancreatic duct and pancreas. AJR Am J Roentgenol. 187(6):1544-53, 2006
                                    15. Nijs E et al: Disorders of the pediatric pancreas: imaging features. Pediatr Radiol. 35(4):358-73; quiz 457, 2005
                                    16. Benya EC: Pancreas and biliary system: imaging of developmental anomalies and diseases unique to children. Radiol Clin North Am. 40(6):1355-62, 2002
                                    17. Jeong HY et al: Adenocarcinoma arising from an ectopic pancreas in the stomach. Endoscopy. 34(12):1014-7, 2002
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Synonyms

                                              • Heterotopic pancreas; pancreatic rests; aberrant or accessory pancreas; pancreatic choristoma; pancreatic adenomyoma
                                            • Definitions

                                              • Pancreatic tissue located outside of normal confines of pancreas and lacking any anatomic, ductal, or vascular connection with main pancreas

                                            IMAGING

                                            • General Features

                                              • Fluoroscopic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Other Modality Findings

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Shamoon D et al: A case of heterotopic pancreatic tissue discovered in the distal esophagus. Case Rep Gastrointest Med. 2020:4695184, 2020
                                                                      2. Wood CG et al: Pancreatitis in the developmentally anomalous pancreas. Abdom Radiol (NY). 45(5):1316-23, 2020
                                                                      3. Yoo J et al: Multiparametric MRI and 18F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions. Eur Radiol. 30(3):1634-43, 2020
                                                                      4. Seddon K et al: Gastric heterotopic pancreas in children: a prospective endoscopic study. J Pediatr Surg. 55(10):2154-58, 2019
                                                                      5. Rezvani M et al: Heterotopic pancreas: histopathologic features, imaging findings, and complications. Radiographics. 37(2):484-99, 2017
                                                                      6. Jang KM et al: Ectopic pancreas in upper gastrointestinal tract: MRI findings with emphasis on differentiation from submucosal tumor. Acta Radiol. 54(10):1107-16, 2013
                                                                      7. Kalaitzakis E et al: Gastric ectopic pancreas: not always an innocent bystander. JOP. 14(6):684-5, 2013
                                                                      8. O'Malley RB et al: Case of the season: ectopic pancreas. Semin Roentgenol. 48(3):188-91, 2013
                                                                      9. Hur BY et al: Gastroduodenal glomus tumors: differentiation from other subepithelial lesions based on dynamic contrast-enhanced CT findings. AJR Am J Roentgenol. 197(6):1351-9, 2011
                                                                      10. Wei R et al: Upper gastrointestinal tract heterotopic pancreas: findings from CT and endoscopic imaging with histopathologic correlation. Clin Imaging. 35(5):353-9, 2011
                                                                      11. Kim JY et al: Ectopic pancreas: CT findings with emphasis on differentiation from small gastrointestinal stromal tumor and leiomyoma. Radiology. 252(1):92-100, 2009
                                                                      12. Nijs EL et al: Congenital and developmental pancreatic anomalies: ultrasound, computed tomography, and magnetic resonance imaging features. Semin Ultrasound CT MR. 28(5):395-401, 2007
                                                                      13. Mortelé KJ et al: Multimodality imaging of pancreatic and biliary congenital anomalies. Radiographics. 26(3):715-31, 2006
                                                                      14. Yu J et al: Congenital anomalies and normal variants of the pancreaticobiliary tract and the pancreas in adults: part 2, Pancreatic duct and pancreas. AJR Am J Roentgenol. 187(6):1544-53, 2006
                                                                      15. Nijs E et al: Disorders of the pediatric pancreas: imaging features. Pediatr Radiol. 35(4):358-73; quiz 457, 2005
                                                                      16. Benya EC: Pancreas and biliary system: imaging of developmental anomalies and diseases unique to children. Radiol Clin North Am. 40(6):1355-62, 2002
                                                                      17. Jeong HY et al: Adenocarcinoma arising from an ectopic pancreas in the stomach. Endoscopy. 34(12):1014-7, 2002