link
Bookmarks
Endolymphatic Sac Tumor
Hilda E. Stambuk, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
0
0
0

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Endolymphatic sac tumor (ELST)
            • Synonyms

              • Adenomatous tumor of ELS, Heffner tumor
            • Definitions

              • Papillary cystadenomatous tumor of ELS

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Angiographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Carlson ML et al: Management of primary and recurrent endolymphatic sac tumors. Otol Neurotol. 34(5):939-43, 2013
                                            2. Eze N et al: De novo development and progression of endolymphatic sac tumour in von hippel-lindau disease: an observational study and literature review. J Neurol Surg B Skull Base. 74(5):259-65, 2013
                                            3. Virk JS et al: Endolymphatic sac tumour: case report and literature review. J Laryngol Otol. 127(4):408-10, 2013
                                            4. Lee KJ et al: Endolymphatic sac tumor presenting with Ménière's disease. Otolaryngol Head Neck Surg. 142(6):915-6, 2010
                                            5. Janse van Rensburg P et al: Magnetic resonance and computed tomography imaging of a grade IV papillary endolymphatic sac tumour. J Neurooncol. 89(2):199-203, 2008
                                            6. Diaz RC et al: Tumors and pseudotumors of the endolymphatic sac. Skull Base. 17(6):379-93, 2007
                                            7. Kang M et al: Imaging features of endolymphatic sac tumours: case report with review of literature. Australas Radiol. 51 Suppl:B199-201, 2007
                                            8. Lalwani AK: Endolymphatic sac tumors in von Hippel-Lindau disease. Arch Otolaryngol Head Neck Surg. 133(9):857, 2007
                                            9. Megerian CA et al: Evaluation and management of endolymphatic sac and duct tumors. Otolaryngol Clin North Am. 40(3):463-78, viii, 2007
                                            10. Bisceglia M et al: Endolymphatic sac papillary tumor (Heffner tumor). Adv Anat Pathol. 13(3):131-8, 2006
                                            11. Löwenheim H et al: Differentiating imaging findings in primary and secondary tumors of the jugular foramen. Neurosurg Rev. 29(1):1-11; discussion 12-13, 2006
                                            12. Patel NP et al: The radiologic diagnosis of endolymphatic sac tumors. Laryngoscope. 116(1):40-6, 2006
                                            13. Saunders NC et al: Metastatic squamous carcinoma with features typical of an endolymphatic sac tumor. Otol Neurotol. 27(5):739-40, 2006
                                            14. Schipper J et al: Endolymphatic sac tumours: surgical management. J Otolaryngol. 35(6):387-94, 2006
                                            15. Hansen MR et al: Surgical outcomes in patients with endolymphatic sac tumors. Laryngoscope. 114(8):1470-4, 2004
                                            16. Jensen RL et al: Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression. J Neurosurg. 100(3):488-97, 2004
                                            17. Cohen JE et al: Endolymphatic sac tumor: staged endovascular-neurosurgical approach. Neurol Res. 25(3):237-40, 2003
                                            18. Devaney KO et al: Endolymphatic sac tumor (low-grade papillary adenocarcinoma) of the temporal bone. Acta Otolaryngol. 123(9):1022-6, 2003
                                            19. Richards PS et al: Endolymphatic sac tumours. J Laryngol Otol. 117(8):666-9, 2003
                                            20. Baltacioglu F et al: MR imaging, CT, and angiography features of endolymphatic sac tumors: report of two cases. Neuroradiology. 44(1):91-6, 2002
                                            21. Ferreira MA et al: Endolymphatic sac tumor: unique features of two cases and review of the literature. Acta Neurochir (Wien). 144(10):1047-53, 2002
                                            22. Joy HM et al: Radiological considerations in the diagnosis of an endolymphatic sac tumour. Clin Radiol. 57(7):652-4, 2002
                                            23. Luff DA et al: Endolymphatic sac tumours. J Laryngol Otol. 116(5):398-401, 2002
                                            24. Horiguchi H et al: Endolymphatic sac tumor associated with a von Hippel-Lindau disease patient: an immunohistochemical study. Mod Pathol. 14(7):727-32, 2001
                                            25. Murphy BA et al: Cytology of endolymphatic sac tumor. Mod Pathol. 14(9):920-4, 2001
                                            26. Richard S et al: Central nervous system hemangioblastomas, endolymphatic sac tumors, and von Hippel-Lindau disease. Neurosurg Rev. 23(1):1-22; discussion 23-4, 2000
                                            27. Gaeta M et al: Sudden unilateral deafness with endolymphatic sac adenocarcinoma: MRI. Neuroradiology. 41(10):799-801, 1999
                                            28. Kempermann G et al: Endolymphatic sac tumours. Histopathology. 33(1):2-10, 1998
                                            29. Roche PH et al: Endolymphatic sac tumors: report of three cases. Neurosurgery. 42(4):927-32, 1998
                                            30. Stendel R et al: Neoplasm of endolymphatic sac origin: clinical, radiological and pathological features. Acta Neurochir (Wien). 140(10):1083-7, 1998
                                            31. Mukherji SK et al: Papillary endolymphatic sac tumors: CT, MR imaging, and angiographic findings in 20 patients. Radiology. 202(3):801-8, 1997
                                            32. Tibbs RE Jr et al: Should endolymphatic sac tumors be considered part of the von Hippel-Lindau complex? Pathology case report. Neurosurgery. 40(4):848-55; discussion 855, 1997
                                            33. Ho VT et al: Low-grade adenocarcinoma of probable endolymphatic sac origin: CT and MR appearance. AJNR Am J Neuroradiol. 17(1):168-70, 1996
                                            34. Levin RJ et al: Aggressive papillary tumors of the temporal bone: an immunohistochemical analysis in tissue culture. Laryngoscope. 106(2 Pt 1):144-7, 1996
                                            35. Feghali JG et al: Aggressive papillary tumors of the endolymphatic sac: clinical and tissue culture characteristics. Am J Otol. 16(6):778-82, 1995
                                            36. Megerian CA et al: Endolymphatic sac tumors: histopathologic confirmation, clinical characterization, and implication in von Hippel-Lindau disease. Laryngoscope. 105(8 Pt 1):801-8, 1995
                                            37. Pollak A et al: Are papillary adenomas endolymphatic sac tumors? Ann Otol Rhinol Laryngol. 104(8):613-9, 1995
                                            38. Lo WW et al: Endolymphatic sac tumors: radiologic appearance. Radiology. 189(1):199-204, 1993
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Endolymphatic sac tumor (ELST)
                                                      • Synonyms

                                                        • Adenomatous tumor of ELS, Heffner tumor
                                                      • Definitions

                                                        • Papillary cystadenomatous tumor of ELS

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Angiographic Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Carlson ML et al: Management of primary and recurrent endolymphatic sac tumors. Otol Neurotol. 34(5):939-43, 2013
                                                                                      2. Eze N et al: De novo development and progression of endolymphatic sac tumour in von hippel-lindau disease: an observational study and literature review. J Neurol Surg B Skull Base. 74(5):259-65, 2013
                                                                                      3. Virk JS et al: Endolymphatic sac tumour: case report and literature review. J Laryngol Otol. 127(4):408-10, 2013
                                                                                      4. Lee KJ et al: Endolymphatic sac tumor presenting with Ménière's disease. Otolaryngol Head Neck Surg. 142(6):915-6, 2010
                                                                                      5. Janse van Rensburg P et al: Magnetic resonance and computed tomography imaging of a grade IV papillary endolymphatic sac tumour. J Neurooncol. 89(2):199-203, 2008
                                                                                      6. Diaz RC et al: Tumors and pseudotumors of the endolymphatic sac. Skull Base. 17(6):379-93, 2007
                                                                                      7. Kang M et al: Imaging features of endolymphatic sac tumours: case report with review of literature. Australas Radiol. 51 Suppl:B199-201, 2007
                                                                                      8. Lalwani AK: Endolymphatic sac tumors in von Hippel-Lindau disease. Arch Otolaryngol Head Neck Surg. 133(9):857, 2007
                                                                                      9. Megerian CA et al: Evaluation and management of endolymphatic sac and duct tumors. Otolaryngol Clin North Am. 40(3):463-78, viii, 2007
                                                                                      10. Bisceglia M et al: Endolymphatic sac papillary tumor (Heffner tumor). Adv Anat Pathol. 13(3):131-8, 2006
                                                                                      11. Löwenheim H et al: Differentiating imaging findings in primary and secondary tumors of the jugular foramen. Neurosurg Rev. 29(1):1-11; discussion 12-13, 2006
                                                                                      12. Patel NP et al: The radiologic diagnosis of endolymphatic sac tumors. Laryngoscope. 116(1):40-6, 2006
                                                                                      13. Saunders NC et al: Metastatic squamous carcinoma with features typical of an endolymphatic sac tumor. Otol Neurotol. 27(5):739-40, 2006
                                                                                      14. Schipper J et al: Endolymphatic sac tumours: surgical management. J Otolaryngol. 35(6):387-94, 2006
                                                                                      15. Hansen MR et al: Surgical outcomes in patients with endolymphatic sac tumors. Laryngoscope. 114(8):1470-4, 2004
                                                                                      16. Jensen RL et al: Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression. J Neurosurg. 100(3):488-97, 2004
                                                                                      17. Cohen JE et al: Endolymphatic sac tumor: staged endovascular-neurosurgical approach. Neurol Res. 25(3):237-40, 2003
                                                                                      18. Devaney KO et al: Endolymphatic sac tumor (low-grade papillary adenocarcinoma) of the temporal bone. Acta Otolaryngol. 123(9):1022-6, 2003
                                                                                      19. Richards PS et al: Endolymphatic sac tumours. J Laryngol Otol. 117(8):666-9, 2003
                                                                                      20. Baltacioglu F et al: MR imaging, CT, and angiography features of endolymphatic sac tumors: report of two cases. Neuroradiology. 44(1):91-6, 2002
                                                                                      21. Ferreira MA et al: Endolymphatic sac tumor: unique features of two cases and review of the literature. Acta Neurochir (Wien). 144(10):1047-53, 2002
                                                                                      22. Joy HM et al: Radiological considerations in the diagnosis of an endolymphatic sac tumour. Clin Radiol. 57(7):652-4, 2002
                                                                                      23. Luff DA et al: Endolymphatic sac tumours. J Laryngol Otol. 116(5):398-401, 2002
                                                                                      24. Horiguchi H et al: Endolymphatic sac tumor associated with a von Hippel-Lindau disease patient: an immunohistochemical study. Mod Pathol. 14(7):727-32, 2001
                                                                                      25. Murphy BA et al: Cytology of endolymphatic sac tumor. Mod Pathol. 14(9):920-4, 2001
                                                                                      26. Richard S et al: Central nervous system hemangioblastomas, endolymphatic sac tumors, and von Hippel-Lindau disease. Neurosurg Rev. 23(1):1-22; discussion 23-4, 2000
                                                                                      27. Gaeta M et al: Sudden unilateral deafness with endolymphatic sac adenocarcinoma: MRI. Neuroradiology. 41(10):799-801, 1999
                                                                                      28. Kempermann G et al: Endolymphatic sac tumours. Histopathology. 33(1):2-10, 1998
                                                                                      29. Roche PH et al: Endolymphatic sac tumors: report of three cases. Neurosurgery. 42(4):927-32, 1998
                                                                                      30. Stendel R et al: Neoplasm of endolymphatic sac origin: clinical, radiological and pathological features. Acta Neurochir (Wien). 140(10):1083-7, 1998
                                                                                      31. Mukherji SK et al: Papillary endolymphatic sac tumors: CT, MR imaging, and angiographic findings in 20 patients. Radiology. 202(3):801-8, 1997
                                                                                      32. Tibbs RE Jr et al: Should endolymphatic sac tumors be considered part of the von Hippel-Lindau complex? Pathology case report. Neurosurgery. 40(4):848-55; discussion 855, 1997
                                                                                      33. Ho VT et al: Low-grade adenocarcinoma of probable endolymphatic sac origin: CT and MR appearance. AJNR Am J Neuroradiol. 17(1):168-70, 1996
                                                                                      34. Levin RJ et al: Aggressive papillary tumors of the temporal bone: an immunohistochemical analysis in tissue culture. Laryngoscope. 106(2 Pt 1):144-7, 1996
                                                                                      35. Feghali JG et al: Aggressive papillary tumors of the endolymphatic sac: clinical and tissue culture characteristics. Am J Otol. 16(6):778-82, 1995
                                                                                      36. Megerian CA et al: Endolymphatic sac tumors: histopathologic confirmation, clinical characterization, and implication in von Hippel-Lindau disease. Laryngoscope. 105(8 Pt 1):801-8, 1995
                                                                                      37. Pollak A et al: Are papillary adenomas endolymphatic sac tumors? Ann Otol Rhinol Laryngol. 104(8):613-9, 1995
                                                                                      38. Lo WW et al: Endolymphatic sac tumors: radiologic appearance. Radiology. 189(1):199-204, 1993