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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Endometrial carcinoma (EC)
Definitions
- Malignant proliferation of abnormal endometrial glands
- Atypical irregular glands with multiple lumina
- Reduced stroma → "back to back" appearance of glands
- Malignant proliferation of abnormal endometrial glands
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kabil Kucur S et al: Role of endometrial power Doppler ultrasound using the international endometrial tumor analysis group classification in predicting intrauterine pathology. Arch Gynecol Obstet. 288(3):649-54, 2013
- Armstrong AJ et al: Diagnosis and management of endometrial hyperplasia. J Minim Invasive Gynecol. 19(5):562-71, 2012
- Breijer MC et al: Capacity of endometrial thickness measurement to diagnose endometrial carcinoma in asymptomatic postmenopausal women: a systematic review and meta-analysis. Ultrasound Obstet Gynecol. 40(6):621-9, 2012
- Van den Bosch T et al: Pre-sampling ultrasound evaluation and assessment of the tissue yield during sampling improves the diagnostic reliability of office endometrial biopsy. J Obstet Gynaecol. 32(2):173-6, 2012
- Jacobs I et al: Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort. Lancet Oncol. 12(1):38-48, 2011
- Menzies R et al: Significance of abnormal sonographic findings in postmenopausal women with and without bleeding. J Obstet Gynaecol Can. 33(9):944-51, 2011
- Odeh M et al: Three-dimensional endometrial volume and 3-dimensional power Doppler analysis in predicting endometrial carcinoma and hyperplasia. Gynecol Oncol. 106(2):348-53, 2007
- Barwick TD et al: Imaging of endometrial adenocarcinoma. Clin Radiol. 61(7):545-55, 2006
- Kirby TO et al: Surgical staging in endometrial cancer. Oncology (Williston Park). 20(1):45-50; discussion 50, 53-4, 63, 2006
- Kumar R et al: Positron emission tomography in gynecological malignancies. Expert Rev Anticancer Ther. 6(7):1033-44, 2006
- Mercé LT et al: Endometrial volume and vascularity measurements by transvaginal three-dimensional ultrasonography and power Doppler angiography in stimulated and tumoral endometria: intraobserver reproducibility. Gynecol Oncol. 100(3):544-50, 2006
- Messiou C et al: MR staging of endometrial carcinoma. Clin Radiol. 61(10):822-32, 2006
- Rackow BW et al: Endometrial cancer and fertility. Curr Opin Obstet Gynecol. 18(3):245-52, 2006
- Takeuchi M et al: Malignant transformation of pelvic endometriosis: MR imaging findings and pathologic correlation. Radiographics. 26(2):407-17, 2006
- Barranger E et al: Lymphatic mapping for gynecologic malignancies. Semin Oncol. 31(3):394-402, 2004
- Moodley M et al: Clinical pathway for the evaluation of postmenopausal bleeding with an emphasis on endometrial cancer detection. J Obstet Gynaecol. 24(7):736-41, 2004
- Tjalma WA et al: The clinical value and the cost-effectiveness of follow-up in endometrial cancer patients. Int J Gynecol Cancer. 14(5):931-7, 2004
- McMeekin DS et al: Endometrial cancer: treatment of nodal metastases. Curr Treat Options Oncol. 4(2):121-30, 2003
- Ascher SM et al: Imaging of cancer of the endometrium. Radiol Clin North Am. 40(3):563-76, 2002
- Sugimura K et al: Postsurgical pelvis: treatment follow-up. Radiol Clin North Am. 40(3):659-80, viii, 2002
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Endometrial carcinoma (EC)
Definitions
- Malignant proliferation of abnormal endometrial glands
- Atypical irregular glands with multiple lumina
- Reduced stroma → "back to back" appearance of glands
- Malignant proliferation of abnormal endometrial glands
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kabil Kucur S et al: Role of endometrial power Doppler ultrasound using the international endometrial tumor analysis group classification in predicting intrauterine pathology. Arch Gynecol Obstet. 288(3):649-54, 2013
- Armstrong AJ et al: Diagnosis and management of endometrial hyperplasia. J Minim Invasive Gynecol. 19(5):562-71, 2012
- Breijer MC et al: Capacity of endometrial thickness measurement to diagnose endometrial carcinoma in asymptomatic postmenopausal women: a systematic review and meta-analysis. Ultrasound Obstet Gynecol. 40(6):621-9, 2012
- Van den Bosch T et al: Pre-sampling ultrasound evaluation and assessment of the tissue yield during sampling improves the diagnostic reliability of office endometrial biopsy. J Obstet Gynaecol. 32(2):173-6, 2012
- Jacobs I et al: Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort. Lancet Oncol. 12(1):38-48, 2011
- Menzies R et al: Significance of abnormal sonographic findings in postmenopausal women with and without bleeding. J Obstet Gynaecol Can. 33(9):944-51, 2011
- Odeh M et al: Three-dimensional endometrial volume and 3-dimensional power Doppler analysis in predicting endometrial carcinoma and hyperplasia. Gynecol Oncol. 106(2):348-53, 2007
- Barwick TD et al: Imaging of endometrial adenocarcinoma. Clin Radiol. 61(7):545-55, 2006
- Kirby TO et al: Surgical staging in endometrial cancer. Oncology (Williston Park). 20(1):45-50; discussion 50, 53-4, 63, 2006
- Kumar R et al: Positron emission tomography in gynecological malignancies. Expert Rev Anticancer Ther. 6(7):1033-44, 2006
- Mercé LT et al: Endometrial volume and vascularity measurements by transvaginal three-dimensional ultrasonography and power Doppler angiography in stimulated and tumoral endometria: intraobserver reproducibility. Gynecol Oncol. 100(3):544-50, 2006
- Messiou C et al: MR staging of endometrial carcinoma. Clin Radiol. 61(10):822-32, 2006
- Rackow BW et al: Endometrial cancer and fertility. Curr Opin Obstet Gynecol. 18(3):245-52, 2006
- Takeuchi M et al: Malignant transformation of pelvic endometriosis: MR imaging findings and pathologic correlation. Radiographics. 26(2):407-17, 2006
- Barranger E et al: Lymphatic mapping for gynecologic malignancies. Semin Oncol. 31(3):394-402, 2004
- Moodley M et al: Clinical pathway for the evaluation of postmenopausal bleeding with an emphasis on endometrial cancer detection. J Obstet Gynaecol. 24(7):736-41, 2004
- Tjalma WA et al: The clinical value and the cost-effectiveness of follow-up in endometrial cancer patients. Int J Gynecol Cancer. 14(5):931-7, 2004
- McMeekin DS et al: Endometrial cancer: treatment of nodal metastases. Curr Treat Options Oncol. 4(2):121-30, 2003
- Ascher SM et al: Imaging of cancer of the endometrium. Radiol Clin North Am. 40(3):563-76, 2002
- Sugimura K et al: Postsurgical pelvis: treatment follow-up. Radiol Clin North Am. 40(3):659-80, viii, 2002
