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Endometrial Hyperplasia
Maryam Rezvani, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Excessive proliferation of endometrial glands with increased ratio of glands to stroma

            IMAGING

            • General Features

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Giannella L et al: Diagnostic accuracy of endometrial thickness for the detection of intra-uterine pathologies and appropriateness of performed hysteroscopies among asymptomatic postmenopausal women. Eur J Obstet Gynecol Reprod Biol. 177:29-33, 2014
                                          2. Griffin Y et al: Radiology of benign disorders of menstruation. Semin Ultrasound CT MR. 31(5):414-32, 2010
                                          3. Smith-Bindman R et al: How thick is too thick? When endometrial thickness should prompt biopsy in postmenopausal women without vaginal bleeding. Ultrasound Obstet Gynecol. 24(5):558-65, 2004
                                          4. Davidson KG et al: Ultrasonographic evaluation of the endometrium in postmenopausal vaginal bleeding. Radiol Clin North Am. 41(4):769-80, 2003
                                          5. Williams PL et al: US of abnormal uterine bleeding. Radiographics. 23(3):703-18, 2003
                                          6. Davis PC et al: Sonohysterographic findings of endometrial and subendometrial conditions. Radiographics. 22(4):803-16, 2002
                                          7. Gupta JK et al: Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta-analysis. Acta Obstet Gynecol Scand. 81(9):799-816, 2002
                                          8. Jorizzo JR et al: Spectrum of endometrial hyperplasia and its mimics on saline hysterosonography. AJR Am J Roentgenol. 179(2):385-9, 2002
                                          9. Reinhold C et al: Postmenopausal bleeding: value of imaging. Radiol Clin North Am. 40(3):527-62, 2002
                                          10. Goldstein RB et al: Evaluation of the woman with postmenopausal bleeding: Society of Radiologists in Ultrasound-Sponsored Consensus Conference statement. J Ultrasound Med. 20(10):1025-36, 2001
                                          11. Nalaboff KM et al: Imaging the endometrium: disease and normal variants. Radiographics. 21(6):1409-24, 2001
                                          12. Smith-Bindman R et al: Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 280(17):1510-7, 1998
                                          13. Lerner JP et al: Use of transvaginal sonography in the evaluation of endometrial hyperplasia and carcinoma. Obstet Gynecol Surv. 51(12):718-25, 1996
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Excessive proliferation of endometrial glands with increased ratio of glands to stroma

                                                    IMAGING

                                                    • General Features

                                                      • MR Findings

                                                        • Ultrasonographic Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Giannella L et al: Diagnostic accuracy of endometrial thickness for the detection of intra-uterine pathologies and appropriateness of performed hysteroscopies among asymptomatic postmenopausal women. Eur J Obstet Gynecol Reprod Biol. 177:29-33, 2014
                                                                                  2. Griffin Y et al: Radiology of benign disorders of menstruation. Semin Ultrasound CT MR. 31(5):414-32, 2010
                                                                                  3. Smith-Bindman R et al: How thick is too thick? When endometrial thickness should prompt biopsy in postmenopausal women without vaginal bleeding. Ultrasound Obstet Gynecol. 24(5):558-65, 2004
                                                                                  4. Davidson KG et al: Ultrasonographic evaluation of the endometrium in postmenopausal vaginal bleeding. Radiol Clin North Am. 41(4):769-80, 2003
                                                                                  5. Williams PL et al: US of abnormal uterine bleeding. Radiographics. 23(3):703-18, 2003
                                                                                  6. Davis PC et al: Sonohysterographic findings of endometrial and subendometrial conditions. Radiographics. 22(4):803-16, 2002
                                                                                  7. Gupta JK et al: Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta-analysis. Acta Obstet Gynecol Scand. 81(9):799-816, 2002
                                                                                  8. Jorizzo JR et al: Spectrum of endometrial hyperplasia and its mimics on saline hysterosonography. AJR Am J Roentgenol. 179(2):385-9, 2002
                                                                                  9. Reinhold C et al: Postmenopausal bleeding: value of imaging. Radiol Clin North Am. 40(3):527-62, 2002
                                                                                  10. Goldstein RB et al: Evaluation of the woman with postmenopausal bleeding: Society of Radiologists in Ultrasound-Sponsored Consensus Conference statement. J Ultrasound Med. 20(10):1025-36, 2001
                                                                                  11. Nalaboff KM et al: Imaging the endometrium: disease and normal variants. Radiographics. 21(6):1409-24, 2001
                                                                                  12. Smith-Bindman R et al: Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 280(17):1510-7, 1998
                                                                                  13. Lerner JP et al: Use of transvaginal sonography in the evaluation of endometrial hyperplasia and carcinoma. Obstet Gynecol Surv. 51(12):718-25, 1996