Inflammatory disease of GI tract characterized by tissue eosinophilia that can involve any or all layers of gut wall
"Eosinophilic gastroenteritis" is a misnomer since patients may have identical histologic findings at any portion of gastrointestinal (GI) tract
Requires 4 criteria for diagnosis
Presence of GI symptoms
Biopsy proof of eosinophilic infiltration of 1 or more areas of GI tract
Absence of eosinophilic involvement of multiple organs outside GI tract
Absence of parasitic infestation
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kindel SJ et al: Eosinophilic esophagitis in children following cardiac transplantation: Association with post-transplant lymphoproliferative disorder and other transplant outcomes. Pediatr Transplant. ePub, 2014
Raheem M et al: The pathophysiology of eosinophilic esophagitis. Front Pediatr. 2:41, 2014
Assa'ad A: Eosinophilic gastrointestinal disorders. Allergy Asthma Proc. 30(1):17-22, 2009
Atkins D et al: Eosinophilic esophagitis: the newest esophageal inflammatory disease. Nat Rev Gastroenterol Hepatol. 6(5):267-78, 2009
Shannon R: Eosinophilic esophagitis in children. Gastroenterol Nurs. 32(2):123-5, 2009
Sheikh RA et al: Unusual presentations of eosinophilic gastroenteritis: case series and review of literature. World J Gastroenterol. 15(17):2156-61, 2009
Whitney-Miller CL et al: Eosinophilic esophagitis: a retrospective review of esophageal biopsy specimens from 1992 to 2004 at an adult academic medical center. Am J Clin Pathol. 131(6):788-92, 2009
Badmos KB et al: Eosinophilic colitis presenting as a right iliac fossa mass--a case report. West Afr J Med. 27(3):175-7, 2008
Inflammatory disease of GI tract characterized by tissue eosinophilia that can involve any or all layers of gut wall
"Eosinophilic gastroenteritis" is a misnomer since patients may have identical histologic findings at any portion of gastrointestinal (GI) tract
Requires 4 criteria for diagnosis
Presence of GI symptoms
Biopsy proof of eosinophilic infiltration of 1 or more areas of GI tract
Absence of eosinophilic involvement of multiple organs outside GI tract
Absence of parasitic infestation
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kindel SJ et al: Eosinophilic esophagitis in children following cardiac transplantation: Association with post-transplant lymphoproliferative disorder and other transplant outcomes. Pediatr Transplant. ePub, 2014
Raheem M et al: The pathophysiology of eosinophilic esophagitis. Front Pediatr. 2:41, 2014
Assa'ad A: Eosinophilic gastrointestinal disorders. Allergy Asthma Proc. 30(1):17-22, 2009
Atkins D et al: Eosinophilic esophagitis: the newest esophageal inflammatory disease. Nat Rev Gastroenterol Hepatol. 6(5):267-78, 2009
Shannon R: Eosinophilic esophagitis in children. Gastroenterol Nurs. 32(2):123-5, 2009
Sheikh RA et al: Unusual presentations of eosinophilic gastroenteritis: case series and review of literature. World J Gastroenterol. 15(17):2156-61, 2009
Whitney-Miller CL et al: Eosinophilic esophagitis: a retrospective review of esophageal biopsy specimens from 1992 to 2004 at an adult academic medical center. Am J Clin Pathol. 131(6):788-92, 2009
Badmos KB et al: Eosinophilic colitis presenting as a right iliac fossa mass--a case report. West Afr J Med. 27(3):175-7, 2008
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