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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Slow-growing tumor resembling ependymal cells
- Likely progenitor cell: Radial glial cell in subventricular zone
- Other ependymal tumors genetically distinct; share some histologic features
- Subependymoma, myxopapillary ependymoma, anaplastic ependymoma
- Slow-growing tumor resembling ependymal cells
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- DomÃnguez-Pinilla N et al: Evaluating the apparent diffusion coefficient in MRI studies as a means of determining paediatric brain tumour stages. Neurologia. ePub, 2015
- Pajtler KW et al: Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups. Cancer Cell. 27(5):728-43, 2015
- Thompson YY et al: Posterior fossa ependymoma: current insights. Childs Nerv Syst. 31(10):1699-706, 2015
- Liu Z et al: Supratentorial cortical ependymoma: case series and review of the literature. Neuropathology. 34(3):243-52, 2014
- Nowak J et al: MRI characteristics of ependymoblastoma: results from 22 centrally reviewed cases. AJNR Am J Neuroradiol. 35(10):1996-2001, 2014
- Ostrom QT et al: CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 16 Suppl 4:iv1-63, 2014
- Rodriguez Gutierrez D et al: Metrics and textural features of MRI diffusion to improve classification of pediatric posterior fossa tumors. AJNR Am J Neuroradiol. 35(5):1009-15, 2014
- Smith AB et al: From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics. 33(1):21-43, 2013
- Witt H et al: Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 20(2):143-57, 2011
- Andreiuolo F et al: Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas. Neuro Oncol. 12(11):1126-34, 2010
- Cuellar-Baena S et al: Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma. Int J Mol Med. 26(6):941-8, 2010
- U-King-Im JM et al: Posterior fossa ependymomas: new radiological classification with surgical correlation. Childs Nerv Syst. 26(12):1765-72, 2010
- Zacharoulis S et al: Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis. Childs Nerv Syst. 26(7):905-11, 2010
- Jaing TH et al: Multivariate analysis of clinical prognostic factors in children with intracranial ependymomas. J Neurooncol. 68(3):255-61, 2004
- Good CD et al: Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? J Neurosurg. 94(1):27-32, 2001
- Akyuz C et al: Intracranial ependymomas in childhood--a retrospective review of sixty-two children. Acta Oncol. 39(1):97-100, 2000
- Palma L et al: The importance of surgery in supratentorial ependymomas. Long-term survival in a series of 23 cases. Childs Nerv Syst. 16(3):170-5, 2000
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Slow-growing tumor resembling ependymal cells
- Likely progenitor cell: Radial glial cell in subventricular zone
- Other ependymal tumors genetically distinct; share some histologic features
- Subependymoma, myxopapillary ependymoma, anaplastic ependymoma
- Slow-growing tumor resembling ependymal cells
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- DomÃnguez-Pinilla N et al: Evaluating the apparent diffusion coefficient in MRI studies as a means of determining paediatric brain tumour stages. Neurologia. ePub, 2015
- Pajtler KW et al: Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups. Cancer Cell. 27(5):728-43, 2015
- Thompson YY et al: Posterior fossa ependymoma: current insights. Childs Nerv Syst. 31(10):1699-706, 2015
- Liu Z et al: Supratentorial cortical ependymoma: case series and review of the literature. Neuropathology. 34(3):243-52, 2014
- Nowak J et al: MRI characteristics of ependymoblastoma: results from 22 centrally reviewed cases. AJNR Am J Neuroradiol. 35(10):1996-2001, 2014
- Ostrom QT et al: CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 16 Suppl 4:iv1-63, 2014
- Rodriguez Gutierrez D et al: Metrics and textural features of MRI diffusion to improve classification of pediatric posterior fossa tumors. AJNR Am J Neuroradiol. 35(5):1009-15, 2014
- Smith AB et al: From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics. 33(1):21-43, 2013
- Witt H et al: Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 20(2):143-57, 2011
- Andreiuolo F et al: Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas. Neuro Oncol. 12(11):1126-34, 2010
- Cuellar-Baena S et al: Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma. Int J Mol Med. 26(6):941-8, 2010
- U-King-Im JM et al: Posterior fossa ependymomas: new radiological classification with surgical correlation. Childs Nerv Syst. 26(12):1765-72, 2010
- Zacharoulis S et al: Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis. Childs Nerv Syst. 26(7):905-11, 2010
- Jaing TH et al: Multivariate analysis of clinical prognostic factors in children with intracranial ependymomas. J Neurooncol. 68(3):255-61, 2004
- Good CD et al: Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? J Neurosurg. 94(1):27-32, 2001
- Akyuz C et al: Intracranial ependymomas in childhood--a retrospective review of sixty-two children. Acta Oncol. 39(1):97-100, 2000
- Palma L et al: The importance of surgery in supratentorial ependymomas. Long-term survival in a series of 23 cases. Childs Nerv Syst. 16(3):170-5, 2000
