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23
5
8
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Ectodermal inclusion cyst
"Pearly" tumor
Definitions
Intracranial epidermoids are congenital inclusion cysts (not "tumors")
Benign, slow-growing congenital lesions derived from ectodermal remnants sequestrated during embryogenesis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Pons Escoda A et al: Imaging of skull vault tumors in adults. Insights Imaging. 11(1):23, 2020
Bobeff EJ et al: Suprasellar Epidermoid Cyst: Case Report of Extended Endoscopic Transsphenoidal Resection and Systematic Review of the Literature. World Neurosurg. 128:514-26, 2019
Hitti FL et al: Endoscopic Resection of a Cerebellopontine Angle Epidermoid Cyst via a Retrosigmoid Approach. J Neurol Surg B Skull Base. 80(Suppl 3):S330, 2019
Ma J et al: Primary intradiploic epidermoid cyst: a case report with literature review. Clin Neuropathol. 38(1):28-32, 2019
Badat N et al: Malignant transformation of epidermoid cyst with diffuse leptomeningeal carcinomatosis on skull base and trigeminal perineural spread. J Neuroradiol. 45(5):337-40, 2018
Gollapudi PR et al: A frontal giant intradiploic giant pearl (epidermoid cyst) with intracranial and extracranial extension: a rare entity. J Pediatr Neurosci. 13(4):480-2, 2018
Twede JV et al: Intraosseous epidermoid cyst of the skull: case study and radiological imaging considerations. Dermatol Online J. 24(7), 2018
Vaz-Guimaraes F et al: Endoscopic endonasal surgery for epidermoid and dermoid cysts: a 10-year experience. J Neurosurg. 1-11, 2018
Aboud E et al: Giant intracranial epidermoids: is total removal feasible? J Neurosurg. 1-14, 2015
Law EK et al: Atypical intracranial epidermoid cysts: rare anomalies with unique radiological features. Case Rep Radiol. 2015:528632, 2015
Demir MK et al: Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation. Diagn Interv Radiol. 20(5):448-52, 2014
Vellutini EA et al: Malignant transformation of intracranial epidermoid cyst. Br J Neurosurg. 28(4):507-9, 2014
Velamati R et al: Meningitis secondary to ruptured epidermoid cyst: case-based review. Pediatr Ann. 42(6):248-51, 2013
Ren X et al: Clinical, radiological, and pathological features of 24 atypical intracranial epidermoid cysts. J Neurosurg. 116(3):611-21, 2012
Li F et al: Hyperdense intracranial epidermoid cysts: a study of 15 cases. Acta Neurochir (Wien). 149(1):31-9; discussion 39, 2007
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Ectodermal inclusion cyst
"Pearly" tumor
Definitions
Intracranial epidermoids are congenital inclusion cysts (not "tumors")
Benign, slow-growing congenital lesions derived from ectodermal remnants sequestrated during embryogenesis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Pons Escoda A et al: Imaging of skull vault tumors in adults. Insights Imaging. 11(1):23, 2020
Bobeff EJ et al: Suprasellar Epidermoid Cyst: Case Report of Extended Endoscopic Transsphenoidal Resection and Systematic Review of the Literature. World Neurosurg. 128:514-26, 2019
Hitti FL et al: Endoscopic Resection of a Cerebellopontine Angle Epidermoid Cyst via a Retrosigmoid Approach. J Neurol Surg B Skull Base. 80(Suppl 3):S330, 2019
Ma J et al: Primary intradiploic epidermoid cyst: a case report with literature review. Clin Neuropathol. 38(1):28-32, 2019
Badat N et al: Malignant transformation of epidermoid cyst with diffuse leptomeningeal carcinomatosis on skull base and trigeminal perineural spread. J Neuroradiol. 45(5):337-40, 2018
Gollapudi PR et al: A frontal giant intradiploic giant pearl (epidermoid cyst) with intracranial and extracranial extension: a rare entity. J Pediatr Neurosci. 13(4):480-2, 2018
Twede JV et al: Intraosseous epidermoid cyst of the skull: case study and radiological imaging considerations. Dermatol Online J. 24(7), 2018
Vaz-Guimaraes F et al: Endoscopic endonasal surgery for epidermoid and dermoid cysts: a 10-year experience. J Neurosurg. 1-11, 2018
Aboud E et al: Giant intracranial epidermoids: is total removal feasible? J Neurosurg. 1-14, 2015
Law EK et al: Atypical intracranial epidermoid cysts: rare anomalies with unique radiological features. Case Rep Radiol. 2015:528632, 2015
Demir MK et al: Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation. Diagn Interv Radiol. 20(5):448-52, 2014
Vellutini EA et al: Malignant transformation of intracranial epidermoid cyst. Br J Neurosurg. 28(4):507-9, 2014
Velamati R et al: Meningitis secondary to ruptured epidermoid cyst: case-based review. Pediatr Ann. 42(6):248-51, 2013
Ren X et al: Clinical, radiological, and pathological features of 24 atypical intracranial epidermoid cysts. J Neurosurg. 116(3):611-21, 2012
Li F et al: Hyperdense intracranial epidermoid cysts: a study of 15 cases. Acta Neurochir (Wien). 149(1):31-9; discussion 39, 2007
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