Benign, nonneoplastic spinal mass composed of cells embryologically derived from epidermal (skin) elements
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Dodson V et al: Epidermoid cyst of the lumbar spine after lumbar puncture: a clinical, radiographic, and pathologic correlation. World Neurosurg. 137:363-6, 2020
Maeda T et al: An epidermoid cyst of the thoracic spine in an elderly patient. World Neurosurg. 127:113-6, 2019
Beechar VB et al: Spinal epidermoid tumors: case report and review of the literature. Neurospine. 15(2):117-22, 2018
Funao H et al: A rare case of intradural and extramedullary epidermoid cyst after repetitive epidural anesthesia: case report and review of the literature. World J Surg Oncol. 15(1):131, 2017
Park MH et al: Iatrogenic intraspinal epidermoid cyst. Korean J Spine. 11(3):195-7, 2014
Yin H et al: Surgery and outcomes of six patients with intradural epidermoid cysts in the lumbar spine. World J Surg Oncol. 12(1):50, 2014
Velamati R et al: Meningitis secondary to ruptured epidermoid cyst: case-based review. Pediatr Ann. 42(6):248-51, 2013
Morita M et al: Intraspinal epidermoid tumor of the cauda equina region: seven cases and a review of the literature. J Spinal Disord Tech. 25(5):292-8, 2012
Gonzalvo A et al: Intramedullary spinal epidermoid cyst of the upper thoracic region. J Clin Neurosci. 16(1):142-4, 2009
Bernard PA: Lumbar punctures: always use a stylette. J Child Neurol. 23(8):969; author reply 969, 2008
Danzer E et al: Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. J Neurosurg Pediatr. 2(6):406-13, 2008
Manara R et al: Chronic cystic lesion of the sacrum: characterisation with diffusion-weighted MR imaging. Radiol Med. 113(5):739-46, 2008
Piana G et al: Epidermoid-cyst of the conus medullaris: usefulness of DWI. J Neuroradiol. 35(5):304-5, 2008
Yen CP et al: Epidermoid cysts associated with thoracic meningocele. Acta Neurochir (Wien). 150(3):305-8; discussion 308-9, 2008
Gao B et al: Mollaret meningitis associated with an intraspinal epidermoid cyst. Pediatrics. 120(1):e220-4, 2007
Gerlach R et al: Large intramedullary abscess of the spinal cord associated with an epidermoid cyst without dermal sinus. Case report. J Neurosurg Spine. 7(3):357-61, 2007
Kukreja K et al: Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful? Pediatr Radiol. 37(6):556-60, 2007
Ogden AT et al: Intramedullary inclusion cysts of the cervicothoracic junction. Report of two cases in adults and review of the literature. J Neurosurg Spine. 7(2):236-42, 2007
Per H et al: Iatrogenic epidermoid tumor: late complication of lumbar puncture. J Child Neurol. 22(3):332-6, 2007
Rajpal S et al: Tethering tracts in spina bifida occulta: revisiting an established nomenclature. J Neurosurg Spine. 7(3):315-22, 2007
Refai D et al: Iatrogenic intradural epidermoid cyst after lumbar puncture. Case illustration. J Neurosurg. 106(4 Suppl):322, 2007
Jeong IH et al: Iatrogenic intraspinal epidermoid tumor: case report. Pediatr Neurosurg. 42(6):395-8, 2006
Tang L et al: Diffusion-weighted imaging distinguishes recurrent epidermoid neoplasm from postoperative arachnoid cyst in the lumbosacral spine. J Comput Assist Tomogr. 30(3):507-9, 2006
Lai SW et al: MRI of epidermoid cyst of the conus medullaris. Spinal Cord. 43(5):320-3, 2005
Bretz A et al: Intraspinal epidermoid cyst successfully treated with radiotherapy: case report. Neurosurgery. 53(6):1429-31; discussion 1431-2, 2003
Park JC et al: Iatrogenic spinal epidermoid tumor. A complication of spinal puncture in an adult. Clin Neurol Neurosurg. 105(4):281-5, 2003
Amato VG et al: Intramedullary epidermoid cyst: preoperative diagnosis and surgical management after MRI introduction. Case report and updating of the literature. J Neurosurg Sci. 46(3-4):122-6, 2002
Avellino AM et al: FLAIR magnetic resonance image of a pediatric spinal epidermoid cyst. Pediatr Neurosurg. 36(4):220-2, 2002
Avellino AM et al: Diffusion-weighted magnetic resonance image of a pediatric spinal epidermoid cyst. Pediatr Neurosurg. 34(6):325-6, 2001
Teksam M et al: Intraspinal epidermoid cyst: diffusion-weighted MRI. Neuroradiology. 43(7):572-4, 2001
Song JH et al: Intraspinal epidermoid cyst occurring 15 years after lipomyelomeningocele repair. Case report. J Neurosurg. 90(2 Suppl):252-4, 1999
Potgieter S et al: Epidermoid tumours associated with lumbar punctures performed in early neonatal life. Dev Med Child Neurol. 40(4):266-9, 1998
Debray MP et al: Epidermoid cyst of the conus medullaris: atypical MRI and angiographic features. Neuroradiology. 38(6):526-8, 1996
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Epidermoid tumor
Definitions
Benign, nonneoplastic spinal mass composed of cells embryologically derived from epidermal (skin) elements
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Dodson V et al: Epidermoid cyst of the lumbar spine after lumbar puncture: a clinical, radiographic, and pathologic correlation. World Neurosurg. 137:363-6, 2020
Maeda T et al: An epidermoid cyst of the thoracic spine in an elderly patient. World Neurosurg. 127:113-6, 2019
Beechar VB et al: Spinal epidermoid tumors: case report and review of the literature. Neurospine. 15(2):117-22, 2018
Funao H et al: A rare case of intradural and extramedullary epidermoid cyst after repetitive epidural anesthesia: case report and review of the literature. World J Surg Oncol. 15(1):131, 2017
Park MH et al: Iatrogenic intraspinal epidermoid cyst. Korean J Spine. 11(3):195-7, 2014
Yin H et al: Surgery and outcomes of six patients with intradural epidermoid cysts in the lumbar spine. World J Surg Oncol. 12(1):50, 2014
Velamati R et al: Meningitis secondary to ruptured epidermoid cyst: case-based review. Pediatr Ann. 42(6):248-51, 2013
Morita M et al: Intraspinal epidermoid tumor of the cauda equina region: seven cases and a review of the literature. J Spinal Disord Tech. 25(5):292-8, 2012
Gonzalvo A et al: Intramedullary spinal epidermoid cyst of the upper thoracic region. J Clin Neurosci. 16(1):142-4, 2009
Bernard PA: Lumbar punctures: always use a stylette. J Child Neurol. 23(8):969; author reply 969, 2008
Danzer E et al: Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. J Neurosurg Pediatr. 2(6):406-13, 2008
Manara R et al: Chronic cystic lesion of the sacrum: characterisation with diffusion-weighted MR imaging. Radiol Med. 113(5):739-46, 2008
Piana G et al: Epidermoid-cyst of the conus medullaris: usefulness of DWI. J Neuroradiol. 35(5):304-5, 2008
Yen CP et al: Epidermoid cysts associated with thoracic meningocele. Acta Neurochir (Wien). 150(3):305-8; discussion 308-9, 2008
Gao B et al: Mollaret meningitis associated with an intraspinal epidermoid cyst. Pediatrics. 120(1):e220-4, 2007
Gerlach R et al: Large intramedullary abscess of the spinal cord associated with an epidermoid cyst without dermal sinus. Case report. J Neurosurg Spine. 7(3):357-61, 2007
Kukreja K et al: Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful? Pediatr Radiol. 37(6):556-60, 2007
Ogden AT et al: Intramedullary inclusion cysts of the cervicothoracic junction. Report of two cases in adults and review of the literature. J Neurosurg Spine. 7(2):236-42, 2007
Per H et al: Iatrogenic epidermoid tumor: late complication of lumbar puncture. J Child Neurol. 22(3):332-6, 2007
Rajpal S et al: Tethering tracts in spina bifida occulta: revisiting an established nomenclature. J Neurosurg Spine. 7(3):315-22, 2007
Refai D et al: Iatrogenic intradural epidermoid cyst after lumbar puncture. Case illustration. J Neurosurg. 106(4 Suppl):322, 2007
Jeong IH et al: Iatrogenic intraspinal epidermoid tumor: case report. Pediatr Neurosurg. 42(6):395-8, 2006
Tang L et al: Diffusion-weighted imaging distinguishes recurrent epidermoid neoplasm from postoperative arachnoid cyst in the lumbosacral spine. J Comput Assist Tomogr. 30(3):507-9, 2006
Lai SW et al: MRI of epidermoid cyst of the conus medullaris. Spinal Cord. 43(5):320-3, 2005
Bretz A et al: Intraspinal epidermoid cyst successfully treated with radiotherapy: case report. Neurosurgery. 53(6):1429-31; discussion 1431-2, 2003
Park JC et al: Iatrogenic spinal epidermoid tumor. A complication of spinal puncture in an adult. Clin Neurol Neurosurg. 105(4):281-5, 2003
Amato VG et al: Intramedullary epidermoid cyst: preoperative diagnosis and surgical management after MRI introduction. Case report and updating of the literature. J Neurosurg Sci. 46(3-4):122-6, 2002
Avellino AM et al: FLAIR magnetic resonance image of a pediatric spinal epidermoid cyst. Pediatr Neurosurg. 36(4):220-2, 2002
Avellino AM et al: Diffusion-weighted magnetic resonance image of a pediatric spinal epidermoid cyst. Pediatr Neurosurg. 34(6):325-6, 2001
Teksam M et al: Intraspinal epidermoid cyst: diffusion-weighted MRI. Neuroradiology. 43(7):572-4, 2001
Song JH et al: Intraspinal epidermoid cyst occurring 15 years after lipomyelomeningocele repair. Case report. J Neurosurg. 90(2 Suppl):252-4, 1999
Potgieter S et al: Epidermoid tumours associated with lumbar punctures performed in early neonatal life. Dev Med Child Neurol. 40(4):266-9, 1998
Debray MP et al: Epidermoid cyst of the conus medullaris: atypical MRI and angiographic features. Neuroradiology. 38(6):526-8, 1996
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