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Epidermoid Cyst
Stamatia Destounis, MD; Selin Carkaci, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Epidermoid cyst
            • Definitions

              • Epidermoid cyst: Benign cutaneous or subcutaneous epithelial cyst, usually arising from obstructed hair follicle
                • Epidermal elements implant within dermis

            IMAGING

            • General Features

              • Mammographic Findings

                • Ultrasonographic Findings

                  • MR Findings

                    • Image-Guided Biopsy

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Paliotta A et al: Epidermal inclusion cyst of the breast: A literature review. Oncol Lett. 11(1):657-660, 2016
                                            2. Giess CS et al: Distinguishing breast skin lesions from superficial breast parenchymal lesions: diagnostic criteria, imaging characteristics, and pitfalls. Radiographics. 31(7):1959-72, 2011
                                            3. Kim HK et al: Subcutaneous epidermal inclusion cysts: ultrasound (US) and MR imaging findings. Skeletal Radiol. 40(11):1415-9, 2011
                                            4. Kalli S et al: Lesions of the skin and superficial tissue at breast MR imaging. Radiographics. 30(7):1891-913, 2010
                                            5. Bergmann-Koester CU et al: Epidermal cyst of the breast mimicking malignancy: clinical, radiological, and histological correlation. Arch Gynecol Obstet. 273(5):312-4, 2006
                                            6. Crystal P et al: Concentric rings within a breast mass on sonography: lamellated keratin in an epidermal inclusion cyst. AJR Am J Roentgenol. 184(3 Suppl):S47-8, 2005
                                            7. Kim HS et al: Spectrum of sonographic findings in superficial breast masses. J Ultrasound Med. 24(5):663-80, 2005
                                            8. Celik V et al: Epidermal inclusion cyst of the breast: clinical, radiologic, and pathologic correlation. Breast J. 10(1):57, 2004
                                            9. Kwak JY et al: Imaging findings in a case of epidermal inclusion cyst arising within the breast parenchyma. J Clin Ultrasound. 32(3):141-3, 2004
                                            10. Kapila K et al: Fine needle aspiration cytology of epidermal inclusion cysts in the male breast. Acta Cytol. 47(2):315-7, 2003
                                            11. Morris PC et al: Epidermal cyst of the breast: detection in a screening programme. Australas Radiol. 43(1):12-5, 1999
                                            12. Davies JD et al: Mammary epidermoid inclusion cysts after wide-core needle biopsies. Histopathology. 31(6):549-51, 1997
                                            13. Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997
                                            14. Cooper RA et al: Epidermal inclusion cysts in the male breast. Can Assoc Radiol J. 47(2):92-3, 1996
                                            15. Chantra PK et al: Circumscribed fibrocystic mastopathy with formation of an epidermal cyst. AJR Am J Roentgenol. 163(4):831-2, 1994
                                            16. Fajardo LL et al: Epidermal inclusion cyst after reduction mammoplasty. Radiology. 186(1):103-6, 1993
                                            17. Shousha S et al: Recurrent epidermal cysts of the breast. Histopathology. 21(3):299-300, 1992
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Epidermoid cyst
                                                      • Definitions

                                                        • Epidermoid cyst: Benign cutaneous or subcutaneous epithelial cyst, usually arising from obstructed hair follicle
                                                          • Epidermal elements implant within dermis

                                                      IMAGING

                                                      • General Features

                                                        • Mammographic Findings

                                                          • Ultrasonographic Findings

                                                            • MR Findings

                                                              • Image-Guided Biopsy

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Paliotta A et al: Epidermal inclusion cyst of the breast: A literature review. Oncol Lett. 11(1):657-660, 2016
                                                                                      2. Giess CS et al: Distinguishing breast skin lesions from superficial breast parenchymal lesions: diagnostic criteria, imaging characteristics, and pitfalls. Radiographics. 31(7):1959-72, 2011
                                                                                      3. Kim HK et al: Subcutaneous epidermal inclusion cysts: ultrasound (US) and MR imaging findings. Skeletal Radiol. 40(11):1415-9, 2011
                                                                                      4. Kalli S et al: Lesions of the skin and superficial tissue at breast MR imaging. Radiographics. 30(7):1891-913, 2010
                                                                                      5. Bergmann-Koester CU et al: Epidermal cyst of the breast mimicking malignancy: clinical, radiological, and histological correlation. Arch Gynecol Obstet. 273(5):312-4, 2006
                                                                                      6. Crystal P et al: Concentric rings within a breast mass on sonography: lamellated keratin in an epidermal inclusion cyst. AJR Am J Roentgenol. 184(3 Suppl):S47-8, 2005
                                                                                      7. Kim HS et al: Spectrum of sonographic findings in superficial breast masses. J Ultrasound Med. 24(5):663-80, 2005
                                                                                      8. Celik V et al: Epidermal inclusion cyst of the breast: clinical, radiologic, and pathologic correlation. Breast J. 10(1):57, 2004
                                                                                      9. Kwak JY et al: Imaging findings in a case of epidermal inclusion cyst arising within the breast parenchyma. J Clin Ultrasound. 32(3):141-3, 2004
                                                                                      10. Kapila K et al: Fine needle aspiration cytology of epidermal inclusion cysts in the male breast. Acta Cytol. 47(2):315-7, 2003
                                                                                      11. Morris PC et al: Epidermal cyst of the breast: detection in a screening programme. Australas Radiol. 43(1):12-5, 1999
                                                                                      12. Davies JD et al: Mammary epidermoid inclusion cysts after wide-core needle biopsies. Histopathology. 31(6):549-51, 1997
                                                                                      13. Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997
                                                                                      14. Cooper RA et al: Epidermal inclusion cysts in the male breast. Can Assoc Radiol J. 47(2):92-3, 1996
                                                                                      15. Chantra PK et al: Circumscribed fibrocystic mastopathy with formation of an epidermal cyst. AJR Am J Roentgenol. 163(4):831-2, 1994
                                                                                      16. Fajardo LL et al: Epidermal inclusion cyst after reduction mammoplasty. Radiology. 186(1):103-6, 1993
                                                                                      17. Shousha S et al: Recurrent epidermal cysts of the breast. Histopathology. 21(3):299-300, 1992