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Epidural Lipomatosis
Kevin R. Moore, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Excessive accumulation of intraspinal fat causing cord compression and neurologic deficits

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nonvascular Interventions

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Andreisek G et al: A systematic review of semiquantitative and qualitative radiologic criteria for the diagnosis of lumbar spinal stenosis. AJR Am J Roentgenol. 201(5):W735-46, 2013
                                    2. Brennan RC et al: Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol. 90(9):1067-74, 2011
                                    3. Al-Khawaja D et al: Spinal epidural lipomatosis--a brief review. J Clin Neurosci. 15(12):1323-6, 2008
                                    4. Fassett DR et al: Spinal epidural lipomatosis: a review of its causes and recommendations for treatment. Neurosurg Focus. 16(4):E11, 2004
                                    5. Geers C et al: Polygonal deformation of the dural sac in lumbar epidural lipomatosis: anatomic explanation by the presence of meningovertebral ligaments. AJNR Am J Neuroradiol. 24(7):1276-82, 2003
                                    6. Payer M et al: Idiopathic symptomatic epidural lipomatosis of the lumbar spine. Acta Neurochir (Wien). 145(4):315-20; discussion 321, 2003
                                    7. Dumont-Fischer D et al: Spinal epidural lipomatosis revealing endogenous Cushing's syndrome. Joint Bone Spine. 69(2):222-5, 2002
                                    8. Lisai P et al: Cauda equina syndrome secondary to idiopathic spinal epidural lipomatosis. Spine (Phila Pa 1976). 26(3):307-9, 2001
                                    9. Citow JS et al: Thoracic epidural lipomatosis with associated syrinx: case report. Surg Neurol. 53(6):589-91, 2000
                                    10. McCullen GM et al: Epidural lipomatosis complicating lumbar steroid injections. J Spinal Disord. 12(6):526-9, 1999
                                    11. Fiirgaard B et al: Spinal epidural lipomatosis. Case report and review of the literature. Scand J Med Sci Sports. 7(6):354-7, 1997
                                    12. Robertson SC et al: Idiopathic spinal epidural lipomatosis. Neurosurgery. 41(1):68-74; discussion 74-5, 1997
                                    13. Benamou PH et al: Epidural lipomatosis not induced by corticosteroid therapy. Three cases including one in a patient with primary Cushing's disease (review of the literature). Rev Rhum Engl Ed. 63(3):207-12, 1996
                                    14. Hierholzer J et al: Epidural lipomatosis: case report and literature review. Neuroradiology. 38(4):343-8, 1996
                                    15. Kumar K et al: Symptomatic epidural lipomatosis secondary to obesity. Case report. J Neurosurg. 85(2):348-50, 1996
                                    16. Provenzale JM et al: Spinal angiolipomas: MR features. AJNR Am J Neuroradiol. 17(4):713-9, 1996
                                    17. Zentner J et al: Spinal epidural lipomatosis as a complication of prolonged corticosteroid therapy. J Neurosurg Sci. 39(1):81-5, 1995
                                    18. Beges C et al: Epidural lipomatosis. Interest of magnetic resonance imaging in a weight-reduction treated case. Spine. 19(2):251-4, 1994
                                    19. Kuhn MJ et al: Lumbar epidural lipomatosis: the "Y" sign of thecal sac compression. Comput Med Imaging Graph. 18(5):367-72, 1994
                                    20. Preul MC et al: Spinal angiolipomas. Report of three cases. J Neurosurg. 78(2):280-6, 1993
                                    21. Roy-Camille R et al: Symptomatic spinal epidural lipomatosis induced by a long-term steroid treatment. Review of the literature and report of two additional cases. Spine. 16(12):1365-71, 1991
                                    22. Healy ME et al: Demonstration by magnetic resonance of symptomatic spinal epidural lipomatosis. Neurosurgery. 21(3):414-5, 1987
                                    23. Randall BC et al: Epidural lipomatosis with lumbar radiculopathy: CT appearance. J Comput Assist Tomogr. 10(6):1039-41, 1986
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Definitions

                                                • Excessive accumulation of intraspinal fat causing cord compression and neurologic deficits

                                              IMAGING

                                              • General Features

                                                • Radiographic Findings

                                                  • CT Findings

                                                    • MR Findings

                                                      • Nonvascular Interventions

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Andreisek G et al: A systematic review of semiquantitative and qualitative radiologic criteria for the diagnosis of lumbar spinal stenosis. AJR Am J Roentgenol. 201(5):W735-46, 2013
                                                                      2. Brennan RC et al: Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol. 90(9):1067-74, 2011
                                                                      3. Al-Khawaja D et al: Spinal epidural lipomatosis--a brief review. J Clin Neurosci. 15(12):1323-6, 2008
                                                                      4. Fassett DR et al: Spinal epidural lipomatosis: a review of its causes and recommendations for treatment. Neurosurg Focus. 16(4):E11, 2004
                                                                      5. Geers C et al: Polygonal deformation of the dural sac in lumbar epidural lipomatosis: anatomic explanation by the presence of meningovertebral ligaments. AJNR Am J Neuroradiol. 24(7):1276-82, 2003
                                                                      6. Payer M et al: Idiopathic symptomatic epidural lipomatosis of the lumbar spine. Acta Neurochir (Wien). 145(4):315-20; discussion 321, 2003
                                                                      7. Dumont-Fischer D et al: Spinal epidural lipomatosis revealing endogenous Cushing's syndrome. Joint Bone Spine. 69(2):222-5, 2002
                                                                      8. Lisai P et al: Cauda equina syndrome secondary to idiopathic spinal epidural lipomatosis. Spine (Phila Pa 1976). 26(3):307-9, 2001
                                                                      9. Citow JS et al: Thoracic epidural lipomatosis with associated syrinx: case report. Surg Neurol. 53(6):589-91, 2000
                                                                      10. McCullen GM et al: Epidural lipomatosis complicating lumbar steroid injections. J Spinal Disord. 12(6):526-9, 1999
                                                                      11. Fiirgaard B et al: Spinal epidural lipomatosis. Case report and review of the literature. Scand J Med Sci Sports. 7(6):354-7, 1997
                                                                      12. Robertson SC et al: Idiopathic spinal epidural lipomatosis. Neurosurgery. 41(1):68-74; discussion 74-5, 1997
                                                                      13. Benamou PH et al: Epidural lipomatosis not induced by corticosteroid therapy. Three cases including one in a patient with primary Cushing's disease (review of the literature). Rev Rhum Engl Ed. 63(3):207-12, 1996
                                                                      14. Hierholzer J et al: Epidural lipomatosis: case report and literature review. Neuroradiology. 38(4):343-8, 1996
                                                                      15. Kumar K et al: Symptomatic epidural lipomatosis secondary to obesity. Case report. J Neurosurg. 85(2):348-50, 1996
                                                                      16. Provenzale JM et al: Spinal angiolipomas: MR features. AJNR Am J Neuroradiol. 17(4):713-9, 1996
                                                                      17. Zentner J et al: Spinal epidural lipomatosis as a complication of prolonged corticosteroid therapy. J Neurosurg Sci. 39(1):81-5, 1995
                                                                      18. Beges C et al: Epidural lipomatosis. Interest of magnetic resonance imaging in a weight-reduction treated case. Spine. 19(2):251-4, 1994
                                                                      19. Kuhn MJ et al: Lumbar epidural lipomatosis: the "Y" sign of thecal sac compression. Comput Med Imaging Graph. 18(5):367-72, 1994
                                                                      20. Preul MC et al: Spinal angiolipomas. Report of three cases. J Neurosurg. 78(2):280-6, 1993
                                                                      21. Roy-Camille R et al: Symptomatic spinal epidural lipomatosis induced by a long-term steroid treatment. Review of the literature and report of two additional cases. Spine. 16(12):1365-71, 1991
                                                                      22. Healy ME et al: Demonstration by magnetic resonance of symptomatic spinal epidural lipomatosis. Neurosurgery. 21(3):414-5, 1987
                                                                      23. Randall BC et al: Epidural lipomatosis with lumbar radiculopathy: CT appearance. J Comput Assist Tomogr. 10(6):1039-41, 1986