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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
TERMINOLOGY
Synonyms
Progressive systemic sclerosis
Definitions
Multisystem disorder of small vessels and connective tissue (collagen vascular disease)
IMAGING
General Features
Radiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Chung JH et al: Imaging features of systemic sclerosis-associated interstitial lung disease. J Vis Exp. 160, 2020
Fraticelli P et al: Videofluorography swallow study in patients with systemic sclerosis: correlation with clinical and radiological features. Clin Exp Rheumatol. 37 Suppl 119(4):108-14, 2019
Lee MH et al: Clinical, imaging, and pathologic features of conditions with combined esophageal and cutaneous manifestations. Radiographics. 39(5):1411-34, 2019
McMahan ZH: Gastrointestinal involvement in systemic sclerosis: an update. Curr Opin Rheumatol. 31(6):561-8, 2019
Orlandi M et al: One year in review 2018: systemic sclerosis. Clin Exp Rheumatol. 36 Suppl 113(4):3-23, 2018
Denton CP et al: Systemic sclerosis. Lancet. 390(10103):1685-99, 2017
Emmanuel A: Current management of the gastrointestinal complications of systemic sclerosis. Nat Rev Gastroenterol Hepatol. 13(8):461-72, 2016
Simeón-Aznar CP et al: Systemic sclerosis sine scleroderma and limited cutaneous systemic sclerosis: similarities and differences. Clin Exp Rheumatol. 32(6 Suppl 86):S-33-40, 2014
Savarino E et al: Gastroesophageal reflux and pulmonary fibrosis in scleroderma: a study using pH-impedance monitoring. Am J Respir Crit Care Med. 179(5):408-13, 2009
Hinchcliff M et al: Systemic sclerosis/scleroderma: a treatable multisystem disease. Am Fam Physician. 78(8):961-8, 2008
Vonk MC et al: Oesophageal dilatation on high-resolution computed tomography scan of the lungs as a sign of scleroderma. Ann Rheum Dis. 67(9):1317-21, 2008
Sifrim D et al: Non-achalasic motor disorders of the oesophagus. Best Pract Res Clin Gastroenterol. 21(4):575-93, 2007
Ntoumazios SK et al: Esophageal involvement in scleroderma: gastroesophageal reflux, the common problem. Semin Arthritis Rheum. 36(3):173-81, 2006
Goldblatt F et al: Antibody-mediated gastrointestinal dysmotility in scleroderma. Gastroenterology. 123(4):1144-50, 2002
Coggins CA et al: Wide-mouthed sacculations in the esophagus: a radiographic finding in scleroderma. AJR Am J Roentgenol. 176(4):953-4, 2001
Duchini A et al: Gastrointestinal hemorrhage in patients with systemic sclerosis and CREST syndrome. Am J Gastroenterol. 93(9):1453-6, 1998
Weston S et al: Clinical and upper gastrointestinal motility features in systemic sclerosis and related disorders. Am J Gastroenterol. 93(7):1085-9, 1998
Lock G et al: Gastrointestinal manifestations of progressive systemic sclerosis. Am J Gastroenterol. 92(5):763-71, 1997
Young MA et al: Gastrointestinal manifestations of scleroderma. Rheum Dis Clin North Am. 22(4):797-823, 1996
Kahan A et al: Gastrointestinal involvement in systemic sclerosis. Clin Dermatol. 12(2):259-65, 1994
Ott DJ: Esophageal motility disorders. Semin Roentgenol. 29(4):321-31, 1994
Levine MS et al: Update on esophageal radiology. AJR Am J Roentgenol. 155(5):933-41, 1990
Marshall JB et al: Gastrointestinal manifestations of mixed connective tissue disease. Gastroenterology. 98(5 Pt 1):1232-8, 1990
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
TERMINOLOGY
Synonyms
Progressive systemic sclerosis
Definitions
Multisystem disorder of small vessels and connective tissue (collagen vascular disease)
IMAGING
General Features
Radiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Chung JH et al: Imaging features of systemic sclerosis-associated interstitial lung disease. J Vis Exp. 160, 2020
Fraticelli P et al: Videofluorography swallow study in patients with systemic sclerosis: correlation with clinical and radiological features. Clin Exp Rheumatol. 37 Suppl 119(4):108-14, 2019
Lee MH et al: Clinical, imaging, and pathologic features of conditions with combined esophageal and cutaneous manifestations. Radiographics. 39(5):1411-34, 2019
McMahan ZH: Gastrointestinal involvement in systemic sclerosis: an update. Curr Opin Rheumatol. 31(6):561-8, 2019
Orlandi M et al: One year in review 2018: systemic sclerosis. Clin Exp Rheumatol. 36 Suppl 113(4):3-23, 2018
Denton CP et al: Systemic sclerosis. Lancet. 390(10103):1685-99, 2017
Emmanuel A: Current management of the gastrointestinal complications of systemic sclerosis. Nat Rev Gastroenterol Hepatol. 13(8):461-72, 2016
Simeón-Aznar CP et al: Systemic sclerosis sine scleroderma and limited cutaneous systemic sclerosis: similarities and differences. Clin Exp Rheumatol. 32(6 Suppl 86):S-33-40, 2014
Savarino E et al: Gastroesophageal reflux and pulmonary fibrosis in scleroderma: a study using pH-impedance monitoring. Am J Respir Crit Care Med. 179(5):408-13, 2009
Hinchcliff M et al: Systemic sclerosis/scleroderma: a treatable multisystem disease. Am Fam Physician. 78(8):961-8, 2008
Vonk MC et al: Oesophageal dilatation on high-resolution computed tomography scan of the lungs as a sign of scleroderma. Ann Rheum Dis. 67(9):1317-21, 2008
Sifrim D et al: Non-achalasic motor disorders of the oesophagus. Best Pract Res Clin Gastroenterol. 21(4):575-93, 2007
Ntoumazios SK et al: Esophageal involvement in scleroderma: gastroesophageal reflux, the common problem. Semin Arthritis Rheum. 36(3):173-81, 2006
Goldblatt F et al: Antibody-mediated gastrointestinal dysmotility in scleroderma. Gastroenterology. 123(4):1144-50, 2002
Coggins CA et al: Wide-mouthed sacculations in the esophagus: a radiographic finding in scleroderma. AJR Am J Roentgenol. 176(4):953-4, 2001
Duchini A et al: Gastrointestinal hemorrhage in patients with systemic sclerosis and CREST syndrome. Am J Gastroenterol. 93(9):1453-6, 1998
Weston S et al: Clinical and upper gastrointestinal motility features in systemic sclerosis and related disorders. Am J Gastroenterol. 93(7):1085-9, 1998
Lock G et al: Gastrointestinal manifestations of progressive systemic sclerosis. Am J Gastroenterol. 92(5):763-71, 1997
Young MA et al: Gastrointestinal manifestations of scleroderma. Rheum Dis Clin North Am. 22(4):797-823, 1996
Kahan A et al: Gastrointestinal involvement in systemic sclerosis. Clin Dermatol. 12(2):259-65, 1994
Ott DJ: Esophageal motility disorders. Semin Roentgenol. 29(4):321-31, 1994