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Gastrointestinal
Diagnosis
Esophagus
Malignant Neoplasms
Esophagus and Esophagogastric Junction Carcinoma
Esophagus and Esophagogastric Junction Carcinoma
Ahmed Ebada Salem, MD; Akram M. Shaaban, MBBCh
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11

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Gross Pathology & Surgical Features

        • Routes of Spread

          • General Features

            • Gross Pathology

              • Microscopic Features

                IMAGING FINDINGS

                • Detection

                  • Staging

                    • Restaging

                      CLINICAL ISSUES

                      • Presentation

                        • Cancer Natural History & Prognosis

                          • Treatment Options

                            REPORTING CHECKLIST

                            • T Staging

                              • N Staging

                                • M Staging

                                  Selected References

                                  1. Foley KG et al: Additional value of EUS in oesophageal cancer patients staged N0 on PET/CT: validation of a prognostic model. Surg Endosc. 32(12):4973-79, 2018
                                  2. Huang FL et al: Esophageal cancer: risk factors, genetic association, and treatment. Asian J Surg. 41(3):210-15, 2018
                                  3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                  4. Kroese TE et al: Detection of distant interval metastases after neoadjuvant therapy for esophageal cancer with 18F-FDG PET(/CT): a systematic review and meta-analysis. Dis Esophagus. 1:31(12), 2018
                                  5. Jain S et al: Pathology of esophageal cancer and Barrett's esophagus. Ann Cardiothorac Surg. 6(2):99-109, 2017
                                  6. Rice TW: Esophageal cancer staging. Korean J Thorac Cardiovasc Surg. 48(3):157-63, 2015
                                  7. Rubenstein JH et al: Epidemiology, diagnosis, and management of esophageal adenocarcinoma. Gastroenterology. 149(2):302-17.e1, 2015
                                  8. Hong SJ et al: New TNM staging system for esophageal cancer: what chest radiologists need to know. Radiographics. 34(6):1722-40, 2014
                                  9. Lee G et al: Clinical implication of PET/MR imaging in preoperative esophageal cancer staging: comparison with PET/CT, endoscopic ultrasonography, and CT. J Nucl Med. 55(8):1242-7, 2014
                                  10. Godoy MC et al: Multimodality imaging evaluation of esophageal cancer: staging, therapy assessment, and complications. Abdom Imaging. 38(5):974-93, 2013
                                  11. Morita M et al: Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention. Int J Clin Oncol. 15(2):126-34, 2010
                                  12. Rice TW et al: 7th edition of the AJCC Cancer Staging Manual: esophagus and esophagogastric junction. Ann Surg Oncol. 17(7):1721-4, 2010
                                  13. Kim TJ et al: Multimodality assessment of esophageal cancer: preoperative staging and monitoring of response to therapy. Radiographics. 29(2):403-21, 2009
                                  14. van Vliet EP et al: Staging investigations for oesophageal cancer: a meta-analysis. Br J Cancer. 98(3):547-57, 2008
                                  15. Kim TJ et al: Postoperative imaging of esophageal cancer: what chest radiologists need to know. Radiographics. 27(2):409-29, 2007
                                  16. Lagarde SM et al: Prognostic factors in adenocarcinoma of the esophagus or gastroesophageal junction. J Clin Oncol. 24(26):4347-55, 2006
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  OVERVIEW

                                  • General Comments

                                    • Classification

                                      PATHOLOGY

                                      • Gross Pathology & Surgical Features

                                        • Routes of Spread

                                          • General Features

                                            • Gross Pathology

                                              • Microscopic Features

                                                IMAGING FINDINGS

                                                • Detection

                                                  • Staging

                                                    • Restaging

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Cancer Natural History & Prognosis

                                                          • Treatment Options

                                                            REPORTING CHECKLIST

                                                            • T Staging

                                                              • N Staging

                                                                • M Staging

                                                                  Selected References

                                                                  1. Foley KG et al: Additional value of EUS in oesophageal cancer patients staged N0 on PET/CT: validation of a prognostic model. Surg Endosc. 32(12):4973-79, 2018
                                                                  2. Huang FL et al: Esophageal cancer: risk factors, genetic association, and treatment. Asian J Surg. 41(3):210-15, 2018
                                                                  3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                                  4. Kroese TE et al: Detection of distant interval metastases after neoadjuvant therapy for esophageal cancer with 18F-FDG PET(/CT): a systematic review and meta-analysis. Dis Esophagus. 1:31(12), 2018
                                                                  5. Jain S et al: Pathology of esophageal cancer and Barrett's esophagus. Ann Cardiothorac Surg. 6(2):99-109, 2017
                                                                  6. Rice TW: Esophageal cancer staging. Korean J Thorac Cardiovasc Surg. 48(3):157-63, 2015
                                                                  7. Rubenstein JH et al: Epidemiology, diagnosis, and management of esophageal adenocarcinoma. Gastroenterology. 149(2):302-17.e1, 2015
                                                                  8. Hong SJ et al: New TNM staging system for esophageal cancer: what chest radiologists need to know. Radiographics. 34(6):1722-40, 2014
                                                                  9. Lee G et al: Clinical implication of PET/MR imaging in preoperative esophageal cancer staging: comparison with PET/CT, endoscopic ultrasonography, and CT. J Nucl Med. 55(8):1242-7, 2014
                                                                  10. Godoy MC et al: Multimodality imaging evaluation of esophageal cancer: staging, therapy assessment, and complications. Abdom Imaging. 38(5):974-93, 2013
                                                                  11. Morita M et al: Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention. Int J Clin Oncol. 15(2):126-34, 2010
                                                                  12. Rice TW et al: 7th edition of the AJCC Cancer Staging Manual: esophagus and esophagogastric junction. Ann Surg Oncol. 17(7):1721-4, 2010
                                                                  13. Kim TJ et al: Multimodality assessment of esophageal cancer: preoperative staging and monitoring of response to therapy. Radiographics. 29(2):403-21, 2009
                                                                  14. van Vliet EP et al: Staging investigations for oesophageal cancer: a meta-analysis. Br J Cancer. 98(3):547-57, 2008
                                                                  15. Kim TJ et al: Postoperative imaging of esophageal cancer: what chest radiologists need to know. Radiographics. 27(2):409-29, 2007
                                                                  16. Lagarde SM et al: Prognostic factors in adenocarcinoma of the esophagus or gastroesophageal junction. J Clin Oncol. 24(26):4347-55, 2006