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Ewing Sarcoma Family of Tumors, Chest Wall
Brett W. Carter, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Ewing sarcoma family of tumors (ESFT)
              • Peripheral primitive neuroectodermal tumor (pPNET)
            • Definitions

              • ESFT includes several malignant neoplasms
                • Ewing sarcoma of bone
                • Extraosseous Ewing sarcoma
                • Askin tumor: pPNET arising from chest wall
                  • Small cell cancer of thoracopulmonary region

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          Selected References

                                          1. Murphey MD et al: From the radiologic pathology archives: ewing sarcoma family of tumors: radiologic-pathologic correlation. Radiographics. 33(3):803-31, 2013
                                          2. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                          3. O'Sullivan P et al: Malignant chest wall neoplasms of bone and cartilage: a pictorial review of CT and MR findings. Br J Radiol. 80(956):678-84, 2007
                                          4. Tateishi U et al: Chest wall tumors: radiologic findings and pathologic correlation: part 2. Malignant tumors. 23(6):1491-508, 2003
                                          5. Gladish GW et al: Primary thoracic sarcomas. Radiographics. 22(3):621-37, 2002
                                          6. Schulman H et al: Thoracoabdominal peripheral primitive neuroectodermal tumors in childhood: radiological features. Eur Radiol. 10(10):1649-52, 2000
                                          7. Sallustio G et al: Diagnostic imaging of primitive neuroectodermal tumour of the chest wall (Askin tumour). Pediatr Radiol. 28(9):697-702, 1998
                                          8. Howman-Giles R et al: Gallium and thallium scintigraphy in pediatric peripheral primitive neuroectodermal tumor (Askin tumor) of the chest wall. J Nucl Med. 36(5):814-6, 1995
                                          9. Sabaté JM et al: Malignant neuroectodermal tumour of the chest wall (Askin tumour): CT and MR findings in eight patients. Clin Radiol. 49(9):634-8, 1994
                                          10. Winer-Muram HT et al: Primitive neuroectodermal tumors of the chest wall (Askin tumors): CT and MR findings. AJR Am J Roentgenol. 161(2):265-8, 1993
                                          11. Fink IJ et al: Malignant thoracopulmonary small-cell ("Askin") tumor. AJR Am J Roentgenol. 145(3):517-20, 1985
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Ewing sarcoma family of tumors (ESFT)
                                                      • Peripheral primitive neuroectodermal tumor (pPNET)
                                                    • Definitions

                                                      • ESFT includes several malignant neoplasms
                                                        • Ewing sarcoma of bone
                                                        • Extraosseous Ewing sarcoma
                                                        • Askin tumor: pPNET arising from chest wall
                                                          • Small cell cancer of thoracopulmonary region

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  Selected References

                                                                                  1. Murphey MD et al: From the radiologic pathology archives: ewing sarcoma family of tumors: radiologic-pathologic correlation. Radiographics. 33(3):803-31, 2013
                                                                                  2. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                                                                  3. O'Sullivan P et al: Malignant chest wall neoplasms of bone and cartilage: a pictorial review of CT and MR findings. Br J Radiol. 80(956):678-84, 2007
                                                                                  4. Tateishi U et al: Chest wall tumors: radiologic findings and pathologic correlation: part 2. Malignant tumors. 23(6):1491-508, 2003
                                                                                  5. Gladish GW et al: Primary thoracic sarcomas. Radiographics. 22(3):621-37, 2002
                                                                                  6. Schulman H et al: Thoracoabdominal peripheral primitive neuroectodermal tumors in childhood: radiological features. Eur Radiol. 10(10):1649-52, 2000
                                                                                  7. Sallustio G et al: Diagnostic imaging of primitive neuroectodermal tumour of the chest wall (Askin tumour). Pediatr Radiol. 28(9):697-702, 1998
                                                                                  8. Howman-Giles R et al: Gallium and thallium scintigraphy in pediatric peripheral primitive neuroectodermal tumor (Askin tumor) of the chest wall. J Nucl Med. 36(5):814-6, 1995
                                                                                  9. Sabaté JM et al: Malignant neuroectodermal tumour of the chest wall (Askin tumour): CT and MR findings in eight patients. Clin Radiol. 49(9):634-8, 1994
                                                                                  10. Winer-Muram HT et al: Primitive neuroectodermal tumors of the chest wall (Askin tumors): CT and MR findings. AJR Am J Roentgenol. 161(2):265-8, 1993
                                                                                  11. Fink IJ et al: Malignant thoracopulmonary small-cell ("Askin") tumor. AJR Am J Roentgenol. 145(3):517-20, 1985