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Extralobar Sequestration
Tyler H. Ternes, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Extralobar sequestration (ELS)
              • Definitions

                • Sequestration: From Latin "sequestrare," meaning "to separate"
                • Sequestered lung
                  • No normal communication to tracheobronchial tree
                  • Systemic blood supply
                • ELS
                  • Supernumerary lung tissue often covered by pleura, separate from adjacent lung

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Angiographic Findings

                        • Prenatal Ultrasound

                          • Prenatal MR

                            • Imaging Recommendations

                              DIFFERENTIAL DIAGNOSIS

                                PATHOLOGY

                                • General Features

                                  • Gross Pathologic & Surgical Features

                                    • Microscopic Features

                                      CLINICAL ISSUES

                                      • Presentation

                                        • Demographics

                                          • Natural History & Prognosis

                                            • Treatment

                                              DIAGNOSTIC CHECKLIST

                                              • Consider

                                                • Image Interpretation Pearls

                                                  Selected References

                                                  1. Gabelloni M et al: Pulmonary sequestration: what the radiologist should know. Clin Imaging. 73:61-72, 2020
                                                  2. Romberg EK et al: Applications of pediatric body CT angiography: what radiologists need to know. AJR Am J Roentgenol. 214(5):1019-30, 2020
                                                  3. Alsumrain M et al: Pulmonary sequestration in adults: a retrospective review of resected and unresected cases. BMC Pulm Med. 18(1):97, 2018
                                                  4. Fukui T et al: Extralobar pulmonary sequestration in the middle mediastinum. Gen Thorac Cardiovasc Surg. 65(8):481-3, 2017
                                                  5. Nagasaka S et al: Rare localized extralobar sequestration with congenital cystic adenomatoid malformation: a case report. Surg Case Rep. 3(1):47, 2017
                                                  6. Walker CM et al: The imaging spectrum of bronchopulmonary sequestration. Curr Probl Diagn Radiol. 43(3):100-14, 2014
                                                  7. Wei Y et al: Pulmonary sequestration: a retrospective analysis of 2625 cases in China. Eur J Cardiothorac Surg. 40(1):e39-42, 2011
                                                  8. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                                  9. Newman B: Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 36(8):773-91, 2006
                                                  10. Deguchi E et al: Intralobar pulmonary sequestration diagnosed by MR angiography. Pediatr Surg Int. 21(7):576-7, 2005
                                                  11. Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
                                                  12. Rosado-de-Christenson ML et al: From the archives of the AFIP. Extralobar sequestration: radiologic-pathologic correlation. Radiographics. 13(2):425-41, 1993
                                                  Related Anatomy
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                                                  Related Differential Diagnoses
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                                                  References
                                                  Tables

                                                  Tables

                                                  KEY FACTS

                                                  • Terminology

                                                    • Imaging

                                                      • Top Differential Diagnoses

                                                        • Pathology

                                                          • Clinical Issues

                                                            • Diagnostic Checklist

                                                              TERMINOLOGY

                                                              • Abbreviations

                                                                • Extralobar sequestration (ELS)
                                                              • Definitions

                                                                • Sequestration: From Latin "sequestrare," meaning "to separate"
                                                                • Sequestered lung
                                                                  • No normal communication to tracheobronchial tree
                                                                  • Systemic blood supply
                                                                • ELS
                                                                  • Supernumerary lung tissue often covered by pleura, separate from adjacent lung

                                                              IMAGING

                                                              • General Features

                                                                • Radiographic Findings

                                                                  • CT Findings

                                                                    • MR Findings

                                                                      • Angiographic Findings

                                                                        • Prenatal Ultrasound

                                                                          • Prenatal MR

                                                                            • Imaging Recommendations

                                                                              DIFFERENTIAL DIAGNOSIS

                                                                                PATHOLOGY

                                                                                • General Features

                                                                                  • Gross Pathologic & Surgical Features

                                                                                    • Microscopic Features

                                                                                      CLINICAL ISSUES

                                                                                      • Presentation

                                                                                        • Demographics

                                                                                          • Natural History & Prognosis

                                                                                            • Treatment

                                                                                              DIAGNOSTIC CHECKLIST

                                                                                              • Consider

                                                                                                • Image Interpretation Pearls

                                                                                                  Selected References

                                                                                                  1. Gabelloni M et al: Pulmonary sequestration: what the radiologist should know. Clin Imaging. 73:61-72, 2020
                                                                                                  2. Romberg EK et al: Applications of pediatric body CT angiography: what radiologists need to know. AJR Am J Roentgenol. 214(5):1019-30, 2020
                                                                                                  3. Alsumrain M et al: Pulmonary sequestration in adults: a retrospective review of resected and unresected cases. BMC Pulm Med. 18(1):97, 2018
                                                                                                  4. Fukui T et al: Extralobar pulmonary sequestration in the middle mediastinum. Gen Thorac Cardiovasc Surg. 65(8):481-3, 2017
                                                                                                  5. Nagasaka S et al: Rare localized extralobar sequestration with congenital cystic adenomatoid malformation: a case report. Surg Case Rep. 3(1):47, 2017
                                                                                                  6. Walker CM et al: The imaging spectrum of bronchopulmonary sequestration. Curr Probl Diagn Radiol. 43(3):100-14, 2014
                                                                                                  7. Wei Y et al: Pulmonary sequestration: a retrospective analysis of 2625 cases in China. Eur J Cardiothorac Surg. 40(1):e39-42, 2011
                                                                                                  8. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                                                                                  9. Newman B: Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 36(8):773-91, 2006
                                                                                                  10. Deguchi E et al: Intralobar pulmonary sequestration diagnosed by MR angiography. Pediatr Surg Int. 21(7):576-7, 2005
                                                                                                  11. Berrocal T et al: Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 24(1):e17, 2004
                                                                                                  12. Rosado-de-Christenson ML et al: From the archives of the AFIP. Extralobar sequestration: radiologic-pathologic correlation. Radiographics. 13(2):425-41, 1993