Extramedullary compensatory formation of blood elements due to decreased medullary hematopoiesis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Merchant R et al: Intracranial hematopoiesis in beta thalassemia: a case series. Indian J Pediatr. 85(8):679-81, 2018
Reddy R: Intracranial extramedullary hematopoiesis in primary myelofibrosis. Neurol India. 65(4):913-4, 2017
Mehta S et al: Intracranial extramedullary haematopoiesis: a case report. Br J Neurosurg. 1-3, 2015
Mughal TI et al: Myelofibrosis-associated complications: pathogenesis, clinical manifestations, and effects on outcomes. Int J Gen Med. 7:89-101, 2014
Singer A et al: Intracranial extramedullary hematopoiesis: a rare cause of headaches. J Neuroimaging. 24(5):524-7, 2014
Ghieda U et al: Progressive spinal cord compression due to epidural extramedullary hematopoiesis in thalassemia intermedia. A case report and literature review. Neuroradiol J. 26(1):111-7, 2013
Palma JA et al: Intracranial extramedullary hematopoiesis associated with multiple myeloma. Neurology. 80(17):1620, 2013
Tefferi A: Primary myelofibrosis: 2013 update on diagnosis, risk-stratification, and management. Am J Hematol. 88(2):141-50, 2013
Eskazan AE et al: Intracranial extramedullary hematopoiesis in patients with thalassemia: a case report and review of the literature. Transfusion. 52(8):1715-20, 2012
Sohawon D et al: Extra-medullary haematopoiesis: a pictorial review of its typical and atypical locations. J Med Imaging Radiat Oncol. 56(5):538-44, 2012
Jiang WX et al: 37-year-old woman with multiple intracranial masses. Brain Pathol. 21(5):607-10, 2011
Zherebitskiy V et al: Extramedullary hematopoiesis involving the central nervous system and surrounding structures. Hum Pathol. 42(10):1524-30, 2011
Debard A et al: Dural localization of extramedullary hematopoiesis. Report of a case. J Neurol. 256(5):837-8, 2009
Tun K et al: Meningeal extramedullary haematopoiesis mimicking subdural hematoma. J Clin Neurosci. 15(2):208-10, 2008
Collins WO et al: Extramedullary hematopoiesis of the paranasal sinuses in sickle cell disease. Otolaryngol Head Neck Surg. 132(6):954-6, 2005
Koch CA et al: Nonhepatosplenic extramedullary hematopoiesis: associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc. 78(10):1223-33, 2003
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Extramedullary hematopoiesis (EMH)
Synonyms
Extramedullary erythropoiesis
Definitions
Extramedullary compensatory formation of blood elements due to decreased medullary hematopoiesis
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Merchant R et al: Intracranial hematopoiesis in beta thalassemia: a case series. Indian J Pediatr. 85(8):679-81, 2018
Reddy R: Intracranial extramedullary hematopoiesis in primary myelofibrosis. Neurol India. 65(4):913-4, 2017
Mehta S et al: Intracranial extramedullary haematopoiesis: a case report. Br J Neurosurg. 1-3, 2015
Mughal TI et al: Myelofibrosis-associated complications: pathogenesis, clinical manifestations, and effects on outcomes. Int J Gen Med. 7:89-101, 2014
Singer A et al: Intracranial extramedullary hematopoiesis: a rare cause of headaches. J Neuroimaging. 24(5):524-7, 2014
Ghieda U et al: Progressive spinal cord compression due to epidural extramedullary hematopoiesis in thalassemia intermedia. A case report and literature review. Neuroradiol J. 26(1):111-7, 2013
Palma JA et al: Intracranial extramedullary hematopoiesis associated with multiple myeloma. Neurology. 80(17):1620, 2013
Tefferi A: Primary myelofibrosis: 2013 update on diagnosis, risk-stratification, and management. Am J Hematol. 88(2):141-50, 2013
Eskazan AE et al: Intracranial extramedullary hematopoiesis in patients with thalassemia: a case report and review of the literature. Transfusion. 52(8):1715-20, 2012
Sohawon D et al: Extra-medullary haematopoiesis: a pictorial review of its typical and atypical locations. J Med Imaging Radiat Oncol. 56(5):538-44, 2012
Jiang WX et al: 37-year-old woman with multiple intracranial masses. Brain Pathol. 21(5):607-10, 2011
Zherebitskiy V et al: Extramedullary hematopoiesis involving the central nervous system and surrounding structures. Hum Pathol. 42(10):1524-30, 2011
Debard A et al: Dural localization of extramedullary hematopoiesis. Report of a case. J Neurol. 256(5):837-8, 2009
Tun K et al: Meningeal extramedullary haematopoiesis mimicking subdural hematoma. J Clin Neurosci. 15(2):208-10, 2008
Collins WO et al: Extramedullary hematopoiesis of the paranasal sinuses in sickle cell disease. Otolaryngol Head Neck Surg. 132(6):954-6, 2005
Koch CA et al: Nonhepatosplenic extramedullary hematopoiesis: associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc. 78(10):1223-33, 2003
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