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Extraosseous Chordoma
Surjith Vattoth, MD, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Extraosseous chordoma
            • Definitions

              • Extraosseous, locally aggressive notochordal tumor
                • Location and presenting signs differ from classic clival chordoma

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Reporting Tips

                                          Selected References

                                          1. Das P et al: Descriptive epidemiology of chordomas in the United States. J Neurooncol. 148(1):173-8, 2020
                                          2. Bayrak S et al: Prevalence of anatomical variants in the clivus: fossa navicularis magna, canalis basilaris medianus, and craniopharyngeal canal. Surg Radiol Anat. 41(4):477-83, 2019
                                          3. Dwianingsih EK et al: Primary chordoma of the nasopharynx: a rare case report and review of the literatures. Case Rep Pathol. 2019:3826521, 2019
                                          4. Hamilton K et al: Pediatric extraosseous sacral chordoma: case report and literature review of embryonic derivation and clinical implications. J Neurosurg Pediatr. 1-6, 2019
                                          5. Boronat S et al: Less common manifestations in TSC. Am J Med Genet C Semin Med Genet. 178(3):348-54, 2018
                                          6. Welzel T et al: Diagnostic accuracy of DW MR imaging in the differentiation of chordomas and chondrosarcomas of the skull base: A 3.0-T MRI study of 105 cases. Eur J Radiol. 105:119-24, 2018
                                          7. Sajisevi M et al: Nasopharyngeal masses arising from embryologic remnants of the clivus: a case series. J Neurol Surg Rep. 76(2):e253-e257, 2015
                                          8. Vasudevan V et al: Chordoma arising from cranial base extending to oropharynx: an unusual presentation. J Maxillofac Oral Surg. 14(Suppl 1):103-7, 2015
                                          9. Yan ZY et al: Primary chordoma in the nasal cavity and nasopharynx: CT and MR imaging findings. AJNR Am J Neuroradiol. 31(2):246-50, 2010
                                          10. Nguyen RP et al: Extraosseous chordoma of the nasopharynx. AJNR Am J Neuroradiol. 30(4):803-7, 2009
                                          11. DiFrancesco LM et al: Extra-axial chordoma. Arch Pathol Lab Med. 130(12):1871-4, 2006
                                          12. Yamaguchi T et al: Incipient chordoma: a report of two cases of early-stage chordoma arising from benign notochordal cell tumors. Mod Pathol. 18(7):1005-10, 2005
                                          13. Wang YP et al: Extraosseous chordoma of the retropharyngeal space. Otolaryngol Head Neck Surg. 130(3):383-5, 2004
                                          14. Nishigaya K et al: Intradural retroclival chordoma without bone involvement: no tumor regrowth 5 years after operation. Case report. J Neurosurg. 88(4):764-8, 1998
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Extraosseous chordoma
                                                    • Definitions

                                                      • Extraosseous, locally aggressive notochordal tumor
                                                        • Location and presenting signs differ from classic clival chordoma

                                                    IMAGING

                                                    • General Features

                                                      • Imaging Recommendations

                                                        • CT Findings

                                                          • MR Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Das P et al: Descriptive epidemiology of chordomas in the United States. J Neurooncol. 148(1):173-8, 2020
                                                                                  2. Bayrak S et al: Prevalence of anatomical variants in the clivus: fossa navicularis magna, canalis basilaris medianus, and craniopharyngeal canal. Surg Radiol Anat. 41(4):477-83, 2019
                                                                                  3. Dwianingsih EK et al: Primary chordoma of the nasopharynx: a rare case report and review of the literatures. Case Rep Pathol. 2019:3826521, 2019
                                                                                  4. Hamilton K et al: Pediatric extraosseous sacral chordoma: case report and literature review of embryonic derivation and clinical implications. J Neurosurg Pediatr. 1-6, 2019
                                                                                  5. Boronat S et al: Less common manifestations in TSC. Am J Med Genet C Semin Med Genet. 178(3):348-54, 2018
                                                                                  6. Welzel T et al: Diagnostic accuracy of DW MR imaging in the differentiation of chordomas and chondrosarcomas of the skull base: A 3.0-T MRI study of 105 cases. Eur J Radiol. 105:119-24, 2018
                                                                                  7. Sajisevi M et al: Nasopharyngeal masses arising from embryologic remnants of the clivus: a case series. J Neurol Surg Rep. 76(2):e253-e257, 2015
                                                                                  8. Vasudevan V et al: Chordoma arising from cranial base extending to oropharynx: an unusual presentation. J Maxillofac Oral Surg. 14(Suppl 1):103-7, 2015
                                                                                  9. Yan ZY et al: Primary chordoma in the nasal cavity and nasopharynx: CT and MR imaging findings. AJNR Am J Neuroradiol. 31(2):246-50, 2010
                                                                                  10. Nguyen RP et al: Extraosseous chordoma of the nasopharynx. AJNR Am J Neuroradiol. 30(4):803-7, 2009
                                                                                  11. DiFrancesco LM et al: Extra-axial chordoma. Arch Pathol Lab Med. 130(12):1871-4, 2006
                                                                                  12. Yamaguchi T et al: Incipient chordoma: a report of two cases of early-stage chordoma arising from benign notochordal cell tumors. Mod Pathol. 18(7):1005-10, 2005
                                                                                  13. Wang YP et al: Extraosseous chordoma of the retropharyngeal space. Otolaryngol Head Neck Surg. 130(3):383-5, 2004
                                                                                  14. Nishigaya K et al: Intradural retroclival chordoma without bone involvement: no tumor regrowth 5 years after operation. Case report. J Neurosurg. 88(4):764-8, 1998