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Extraskeletal Myxoid Chondrosarcoma
Catherine C. Roberts, MD; B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Chordoid sarcoma, tendosynovial sarcoma
          • Definitions

            • Rare malignant soft tissue tumor of uncertain differentiation with hemorrhagic, multinodular appearance

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Oike N et al: Extraskeletal myxoid chondrosarcoma arising in the femoral vein: a case report. Skeletal Radiol. 43(10):1465-9, 2014
                                    2. Bhamra JS et al: Intra-articular extraskeletal myxoid chondrosarcoma of the ankle. Skeletal Radiol. 41(8):1017-20, 2012
                                    3. Weiss SW et al: Cartilaginous soft tissue tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 1023-31, 2008
                                    4. Ehara S et al: Skeletal recurrences and metastases of extraskeletal myxoid chondrosarcoma. Skeletal Radiol. 36(9):823-7, 2007
                                    5. Kransdorf MJ et al: Extraskeletal osseous and cartilaginous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 470-2, 2006
                                    6. Tateishi U et al: MRI features of extraskeletal myxoid chondrosarcoma. Skeletal Radiol. 35(1):27-33, 2006
                                    7. Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
                                    8. Lucas DR et al: Extraskeletal myxoid chondrosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 213-5, 2002
                                    9. Ryan JM et al: Metastases to the liver from extraskeletal myxoid chondrosarcoma and successful treatment with percutaneous ethanol injection. Clin Radiol. 55(4):314-7, 2000
                                    10. Takeda A et al: Extraskeletal myxoid chondrosarcoma with multiple skeletal metastases. J Orthop Sci. 5(2):171-4, 2000
                                    11. Gebhardt MC et al: Extraskeletal myxoid chondrosarcoma of the knee. Skeletal Radiol. 28(6):354-8, 1999
                                    12. Sciot R et al: t(9;22)(q22-31;q11-12) is a consistent marker of extraskeletal myxoid chondrosarcoma: evaluation of three cases. Mod Pathol. 8(7):765-8, 1995
                                    13. Disler DG et al: Extensive skeletal metastases from chondrosarcoma without pulmonary involvement. Skeletal Radiol. 22(8):595-9, 1993
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Synonyms

                                              • Chordoid sarcoma, tendosynovial sarcoma
                                            • Definitions

                                              • Rare malignant soft tissue tumor of uncertain differentiation with hemorrhagic, multinodular appearance

                                            IMAGING

                                            • General Features

                                              • CT Findings

                                                • MR Findings

                                                  • Nuclear Medicine Findings

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Staging, Grading, & Classification

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Oike N et al: Extraskeletal myxoid chondrosarcoma arising in the femoral vein: a case report. Skeletal Radiol. 43(10):1465-9, 2014
                                                                      2. Bhamra JS et al: Intra-articular extraskeletal myxoid chondrosarcoma of the ankle. Skeletal Radiol. 41(8):1017-20, 2012
                                                                      3. Weiss SW et al: Cartilaginous soft tissue tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 1023-31, 2008
                                                                      4. Ehara S et al: Skeletal recurrences and metastases of extraskeletal myxoid chondrosarcoma. Skeletal Radiol. 36(9):823-7, 2007
                                                                      5. Kransdorf MJ et al: Extraskeletal osseous and cartilaginous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 470-2, 2006
                                                                      6. Tateishi U et al: MRI features of extraskeletal myxoid chondrosarcoma. Skeletal Radiol. 35(1):27-33, 2006
                                                                      7. Murphey MD et al: From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 23(5):1245-78, 2003
                                                                      8. Lucas DR et al: Extraskeletal myxoid chondrosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 213-5, 2002
                                                                      9. Ryan JM et al: Metastases to the liver from extraskeletal myxoid chondrosarcoma and successful treatment with percutaneous ethanol injection. Clin Radiol. 55(4):314-7, 2000
                                                                      10. Takeda A et al: Extraskeletal myxoid chondrosarcoma with multiple skeletal metastases. J Orthop Sci. 5(2):171-4, 2000
                                                                      11. Gebhardt MC et al: Extraskeletal myxoid chondrosarcoma of the knee. Skeletal Radiol. 28(6):354-8, 1999
                                                                      12. Sciot R et al: t(9;22)(q22-31;q11-12) is a consistent marker of extraskeletal myxoid chondrosarcoma: evaluation of three cases. Mod Pathol. 8(7):765-8, 1995
                                                                      13. Disler DG et al: Extensive skeletal metastases from chondrosarcoma without pulmonary involvement. Skeletal Radiol. 22(8):595-9, 1993