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Fever of Unknown Origin
Andrew T. Trout, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        IMAGING

        • F-18 FDG PET/CT Findings

          DIFFERENTIAL DIAGNOSIS

            CLINICAL ISSUES

            • Demographics

              • Treatment

                • Background

                  Selected References

                  1. Smids C et al: A comparison of the diagnostic value of MRI and 18F-FDG-PET/CT in suspected spondylodiscitis. Infection. 45(1):41-49, 2017
                  2. Besson FL et al: Contribution of (18)F-FDG PET in the diagnostic assessment of fever of unknown origin (FUO): a stratification-based meta-analysis. Eur J Nucl Med Mol Imaging. 43(10):1887-95, 2016
                  3. Takeuchi M et al: Nuclear imaging for classic fever of unknown origin: meta-analysis. J Nucl Med. 57(12):1913-1919, 2016
                  4. Balink H et al: ¹⁸F-FDG PET/CT in inflammation of unknown origin: a cost-effectiveness pilot-study. Eur J Nucl Med Mol Imaging. 42(9):1408-13, 2015
                  5. Balink H et al: The predictive value of C-reactive protein and erythrocyte sedimentation rate for 18F-FDG PET/CT outcome in patients with fever and inflammation of unknown origin. Nucl Med Commun. 36(6):604-9, 2015
                  6. Okuyucu K et al: Evaluation of predictor variables of diagnostic [18F] FDG-PET/CT in fever of unknown origin. Q J Nucl Med Mol Imaging. 2015
                  7. Buch-Olsen KM et al: 18F-FDG-PET/CT in fever of unknown origin: clinical value. Nucl Med Commun. 35(9):955-60, 2014
                  8. del Rosal T et al: ¹⁸F-FDG PET/CT in the diagnosis of occult bacterial infections in children. Eur J Pediatr. 172(8):1111-5, 2013
                  9. Hao R et al: Diagnostic performance of 18F-FDG PET/CT in patients with fever of unknown origin: a meta-analysis. Nucl Med Commun. 34(7):682-8, 2013
                  10. Seshadri N et al: Superiority of 18F-FDG PET compared to 111In-labelled leucocyte scintigraphy in the evaluation of fever of unknown origin. J Infect. 65(1):71-9, 2012
                  11. Chow A et al: Fever of unknown origin in children: a systematic review. World J Pediatr. 7(1):5-10, 2011
                  12. Jasper N et al: Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation. Eur J Nucl Med Mol Imaging. 37(1):136-45, 2010
                  13. Knockaert DC et al: Fever of unknown origin in adults: 40 years on. J Intern Med. 253(3):263-75, 2003
                  Related Anatomy
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                  Related Differential Diagnoses
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                  References
                  Tables

                  Tables

                  KEY FACTS

                  • Imaging

                    • Top Differential Diagnoses

                      • Clinical Issues

                        IMAGING

                        • F-18 FDG PET/CT Findings

                          DIFFERENTIAL DIAGNOSIS

                            CLINICAL ISSUES

                            • Demographics

                              • Treatment

                                • Background

                                  Selected References

                                  1. Smids C et al: A comparison of the diagnostic value of MRI and 18F-FDG-PET/CT in suspected spondylodiscitis. Infection. 45(1):41-49, 2017
                                  2. Besson FL et al: Contribution of (18)F-FDG PET in the diagnostic assessment of fever of unknown origin (FUO): a stratification-based meta-analysis. Eur J Nucl Med Mol Imaging. 43(10):1887-95, 2016
                                  3. Takeuchi M et al: Nuclear imaging for classic fever of unknown origin: meta-analysis. J Nucl Med. 57(12):1913-1919, 2016
                                  4. Balink H et al: ¹⁸F-FDG PET/CT in inflammation of unknown origin: a cost-effectiveness pilot-study. Eur J Nucl Med Mol Imaging. 42(9):1408-13, 2015
                                  5. Balink H et al: The predictive value of C-reactive protein and erythrocyte sedimentation rate for 18F-FDG PET/CT outcome in patients with fever and inflammation of unknown origin. Nucl Med Commun. 36(6):604-9, 2015
                                  6. Okuyucu K et al: Evaluation of predictor variables of diagnostic [18F] FDG-PET/CT in fever of unknown origin. Q J Nucl Med Mol Imaging. 2015
                                  7. Buch-Olsen KM et al: 18F-FDG-PET/CT in fever of unknown origin: clinical value. Nucl Med Commun. 35(9):955-60, 2014
                                  8. del Rosal T et al: ¹⁸F-FDG PET/CT in the diagnosis of occult bacterial infections in children. Eur J Pediatr. 172(8):1111-5, 2013
                                  9. Hao R et al: Diagnostic performance of 18F-FDG PET/CT in patients with fever of unknown origin: a meta-analysis. Nucl Med Commun. 34(7):682-8, 2013
                                  10. Seshadri N et al: Superiority of 18F-FDG PET compared to 111In-labelled leucocyte scintigraphy in the evaluation of fever of unknown origin. J Infect. 65(1):71-9, 2012
                                  11. Chow A et al: Fever of unknown origin in children: a systematic review. World J Pediatr. 7(1):5-10, 2011
                                  12. Jasper N et al: Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation. Eur J Nucl Med Mol Imaging. 37(1):136-45, 2010
                                  13. Knockaert DC et al: Fever of unknown origin in adults: 40 years on. J Intern Med. 253(3):263-75, 2003