Locally aggressive with tendency to slowly infiltrate adjacent tissues
Frequently recurs but lacks metastatic disease
IMAGING
General Features
Radiographic Findings
CT Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Zanchetta E et al: Magnetic resonance imaging patterns of tumor response to chemotherapy in desmoid-type fibromatosis. Cancer Med. 10(13):4356-65, 2021
Davis JL et al: Pediatric and infantile fibroblastic/myofibroblastic tumors in the molecular era. Surg Pathol Clin. 13(4):739-62, 2020
Garcia-Ortega DY et al: Desmoid-type fibromatosis. Cancers (Basel). 12(7), 2020
Navarro OM: Pearls and pitfalls in the imaging of soft-tissue masses in children. Semin Ultrasound CT MR. 41(5):498-512, 2020
Caro-DomÃnguez P et al: Imaging appearances of soft-tissue tumors of the pediatric foot: review of a 15-year experience at a tertiary pediatric hospital. Pediatr Radiol. 47(12):1555-71, 2017
Sargar KM et al: Pediatric fibroblastic and myofibroblastic tumors: a pictorial review. Radiographics. 36(4):1195-214, 2016
He XD et al: Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: analysis of 114 patients at a single institution. Eur J Surg Oncol. 41(8):1013-9, 2015
Otero S et al: Desmoid-type fibromatosis. Clin Radiol. 70(9):1038-45, 2015
Xu H et al: Desmoid-type fibromatosis of the thorax: CT, MRI, and FDG PET characteristics in a large series from a tertiary referral center. Medicine (Baltimore). 94(38):e1547, 2015
Zhou H et al: Abdominal wall desmoid tumor during pregnancy: case report and literature review. Clin Exp Obstet Gynecol. 42(2):253-8, 2015
Oka K et al: Usefulness of diffusion-weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors. J Magn Reson Imaging. 33(1):189-93, 2011
Meazza C et al: Aggressive fibromatosis in children and adolescents: the Italian experience. Cancer. 116(1):233-40, 2010
Wu C et al: Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Res. 70(19):7690-8, 2010
Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
Buitendijk S et al: Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature. Cancer. 104(5):1090-9, 2005
Kingston CA et al: Imaging of desmoid fibromatosis in pediatric patients. AJR Am J Roentgenol. 178(1):191-9, 2002
Sorensen A et al: Treatment of aggressive fibromatosis: a retrospective study of 72 patients followed for 1-27 years. Acta Orthop Scand. 73(2):213-9, 2002
Netscher DT et al: Infantile myofibromatosis: case report of a solitary hand lesion with emphasis on differential diagnosis and management. Ann Plast Surg. 46(1):62-7, 2001
Ahn JM et al: Infantile fibromatosis in childhood: findings on MR imaging and pathologic correlation. Clin Radiol. 55(1):19-24, 2000
Mehrotra AK et al: Fibromatoses of the extremities: clinicopathologic study of 36 cases. J Surg Oncol. 74(4):291-6, 2000
Eich GF et al: Fibrous tumours in children: imaging features of a heterogeneous group of disorders. Pediatr Radiol. 28(7):500-9, 1998
Hartman TE et al: MR imaging of extraabdominal desmoids: differentiation from other neoplasms. AJR Am J Roentgenol. 158(3):581-5, 1992
Liu P et al: MRI of fibromatosis: with pathologic correlation. Pediatr Radiol. 22(8):587-9, 1992
O'Keefe F et al: Magnetic resonance imaging in aggressive fibromatosis. Clin Radiol. 42(3):170-3, 1990
Hudson TM et al: Aggressive fibromatosis: evaluation by computed tomography and angiography. Radiology. 150(2):495-501, 1984
Locally aggressive with tendency to slowly infiltrate adjacent tissues
Frequently recurs but lacks metastatic disease
IMAGING
General Features
Radiographic Findings
CT Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Zanchetta E et al: Magnetic resonance imaging patterns of tumor response to chemotherapy in desmoid-type fibromatosis. Cancer Med. 10(13):4356-65, 2021
Davis JL et al: Pediatric and infantile fibroblastic/myofibroblastic tumors in the molecular era. Surg Pathol Clin. 13(4):739-62, 2020
Garcia-Ortega DY et al: Desmoid-type fibromatosis. Cancers (Basel). 12(7), 2020
Navarro OM: Pearls and pitfalls in the imaging of soft-tissue masses in children. Semin Ultrasound CT MR. 41(5):498-512, 2020
Caro-DomÃnguez P et al: Imaging appearances of soft-tissue tumors of the pediatric foot: review of a 15-year experience at a tertiary pediatric hospital. Pediatr Radiol. 47(12):1555-71, 2017
Sargar KM et al: Pediatric fibroblastic and myofibroblastic tumors: a pictorial review. Radiographics. 36(4):1195-214, 2016
He XD et al: Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: analysis of 114 patients at a single institution. Eur J Surg Oncol. 41(8):1013-9, 2015
Otero S et al: Desmoid-type fibromatosis. Clin Radiol. 70(9):1038-45, 2015
Xu H et al: Desmoid-type fibromatosis of the thorax: CT, MRI, and FDG PET characteristics in a large series from a tertiary referral center. Medicine (Baltimore). 94(38):e1547, 2015
Zhou H et al: Abdominal wall desmoid tumor during pregnancy: case report and literature review. Clin Exp Obstet Gynecol. 42(2):253-8, 2015
Oka K et al: Usefulness of diffusion-weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors. J Magn Reson Imaging. 33(1):189-93, 2011
Meazza C et al: Aggressive fibromatosis in children and adolescents: the Italian experience. Cancer. 116(1):233-40, 2010
Wu C et al: Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Res. 70(19):7690-8, 2010
Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
Buitendijk S et al: Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature. Cancer. 104(5):1090-9, 2005
Kingston CA et al: Imaging of desmoid fibromatosis in pediatric patients. AJR Am J Roentgenol. 178(1):191-9, 2002
Sorensen A et al: Treatment of aggressive fibromatosis: a retrospective study of 72 patients followed for 1-27 years. Acta Orthop Scand. 73(2):213-9, 2002
Netscher DT et al: Infantile myofibromatosis: case report of a solitary hand lesion with emphasis on differential diagnosis and management. Ann Plast Surg. 46(1):62-7, 2001
Ahn JM et al: Infantile fibromatosis in childhood: findings on MR imaging and pathologic correlation. Clin Radiol. 55(1):19-24, 2000
Mehrotra AK et al: Fibromatoses of the extremities: clinicopathologic study of 36 cases. J Surg Oncol. 74(4):291-6, 2000
Eich GF et al: Fibrous tumours in children: imaging features of a heterogeneous group of disorders. Pediatr Radiol. 28(7):500-9, 1998
Hartman TE et al: MR imaging of extraabdominal desmoids: differentiation from other neoplasms. AJR Am J Roentgenol. 158(3):581-5, 1992
Liu P et al: MRI of fibromatosis: with pathologic correlation. Pediatr Radiol. 22(8):587-9, 1992
O'Keefe F et al: Magnetic resonance imaging in aggressive fibromatosis. Clin Radiol. 42(3):170-3, 1990
Hudson TM et al: Aggressive fibromatosis: evaluation by computed tomography and angiography. Radiology. 150(2):495-501, 1984
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