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Fibromatosis
Christopher G. Anton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Aggressive fibromatosis renamed as desmoid-type fibromatosis by WHO
            • Aggressive fibromatosis, extraabdominal desmoid tumor, musculoaponeurotic fibromatosis
          • Definitions

            • Group of benign disorders with fibrous growth & tendency to slowly infiltrate adjacent tissues
            • Frequently recurs but lacks metastatic disease

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. He XD et al: Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: analysis of 114 patients at a single institution. Eur J Surg Oncol. 41(8):1013-9, 2015
                                          2. Otero S et al: Desmoid-type fibromatosis. Clin Radiol. 70(9):1038-45, 2015
                                          3. Xu H et al: Desmoid-type fibromatosis of the thorax: CT, MRI, and FDG PET characteristics in a large series from a tertiary referral center. Medicine (Baltimore). 94(38):e1547, 2015
                                          4. Zhou H et al: Abdominal wall desmoid tumor during pregnancy: case report and literature review. Clin Exp Obstet Gynecol. 42(2):253-8, 2015
                                          5. Oka K et al: Usefulness of diffusion-weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors. J Magn Reson Imaging. 33(1):189-93, 2011
                                          6. Meazza C et al: Aggressive fibromatosis in children and adolescents: the Italian experience. Cancer. 116(1):233-40, 2010
                                          7. Wu C et al: Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Res. 70(19):7690-8, 2010
                                          8. Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
                                          9. Buitendijk S et al: Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature. Cancer. 104(5):1090-9, 2005
                                          10. Kingston CA et al: Imaging of desmoid fibromatosis in pediatric patients. AJR Am J Roentgenol. 178(1):191-9, 2002
                                          11. Sorensen A et al: Treatment of aggressive fibromatosis: a retrospective study of 72 patients followed for 1-27 years. Acta Orthop Scand. 73(2):213-9, 2002
                                          12. Netscher DT et al: Infantile myofibromatosis: case report of a solitary hand lesion with emphasis on differential diagnosis and management. Ann Plast Surg. 46(1):62-7, 2001
                                          13. Ahn JM et al: Infantile fibromatosis in childhood: findings on MR imaging and pathologic correlation. Clin Radiol. 55(1):19-24, 2000
                                          14. Mehrotra AK et al: Fibromatoses of the extremities: clinicopathologic study of 36 cases. J Surg Oncol. 74(4):291-6, 2000
                                          15. Eich GF et al: Fibrous tumours in children: imaging features of a heterogeneous group of disorders. Pediatr Radiol. 28(7):500-9, 1998
                                          16. Hartman TE et al: MR imaging of extraabdominal desmoids: differentiation from other neoplasms. AJR Am J Roentgenol. 158(3):581-5, 1992
                                          17. Liu P et al: MRI of fibromatosis: with pathologic correlation. Pediatr Radiol. 22(8):587-9, 1992
                                          18. O'Keefe F et al: Magnetic resonance imaging in aggressive fibromatosis. Clin Radiol. 42(3):170-3, 1990
                                          19. Hudson TM et al: Aggressive fibromatosis: evaluation by computed tomography and angiography. Radiology. 150(2):495-501, 1984
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Aggressive fibromatosis renamed as desmoid-type fibromatosis by WHO
                                                    • Aggressive fibromatosis, extraabdominal desmoid tumor, musculoaponeurotic fibromatosis
                                                  • Definitions

                                                    • Group of benign disorders with fibrous growth & tendency to slowly infiltrate adjacent tissues
                                                    • Frequently recurs but lacks metastatic disease

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Angiographic Findings

                                                              • Nuclear Medicine Findings

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. He XD et al: Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: analysis of 114 patients at a single institution. Eur J Surg Oncol. 41(8):1013-9, 2015
                                                                                  2. Otero S et al: Desmoid-type fibromatosis. Clin Radiol. 70(9):1038-45, 2015
                                                                                  3. Xu H et al: Desmoid-type fibromatosis of the thorax: CT, MRI, and FDG PET characteristics in a large series from a tertiary referral center. Medicine (Baltimore). 94(38):e1547, 2015
                                                                                  4. Zhou H et al: Abdominal wall desmoid tumor during pregnancy: case report and literature review. Clin Exp Obstet Gynecol. 42(2):253-8, 2015
                                                                                  5. Oka K et al: Usefulness of diffusion-weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors. J Magn Reson Imaging. 33(1):189-93, 2011
                                                                                  6. Meazza C et al: Aggressive fibromatosis in children and adolescents: the Italian experience. Cancer. 116(1):233-40, 2010
                                                                                  7. Wu C et al: Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Res. 70(19):7690-8, 2010
                                                                                  8. Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
                                                                                  9. Buitendijk S et al: Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature. Cancer. 104(5):1090-9, 2005
                                                                                  10. Kingston CA et al: Imaging of desmoid fibromatosis in pediatric patients. AJR Am J Roentgenol. 178(1):191-9, 2002
                                                                                  11. Sorensen A et al: Treatment of aggressive fibromatosis: a retrospective study of 72 patients followed for 1-27 years. Acta Orthop Scand. 73(2):213-9, 2002
                                                                                  12. Netscher DT et al: Infantile myofibromatosis: case report of a solitary hand lesion with emphasis on differential diagnosis and management. Ann Plast Surg. 46(1):62-7, 2001
                                                                                  13. Ahn JM et al: Infantile fibromatosis in childhood: findings on MR imaging and pathologic correlation. Clin Radiol. 55(1):19-24, 2000
                                                                                  14. Mehrotra AK et al: Fibromatoses of the extremities: clinicopathologic study of 36 cases. J Surg Oncol. 74(4):291-6, 2000
                                                                                  15. Eich GF et al: Fibrous tumours in children: imaging features of a heterogeneous group of disorders. Pediatr Radiol. 28(7):500-9, 1998
                                                                                  16. Hartman TE et al: MR imaging of extraabdominal desmoids: differentiation from other neoplasms. AJR Am J Roentgenol. 158(3):581-5, 1992
                                                                                  17. Liu P et al: MRI of fibromatosis: with pathologic correlation. Pediatr Radiol. 22(8):587-9, 1992
                                                                                  18. O'Keefe F et al: Magnetic resonance imaging in aggressive fibromatosis. Clin Radiol. 42(3):170-3, 1990
                                                                                  19. Hudson TM et al: Aggressive fibromatosis: evaluation by computed tomography and angiography. Radiology. 150(2):495-501, 1984