Rare sarcoma composed of relatively monomorphic fibroblastic tumor cells with variable collagen production and often herringbone architecture
Pathologic diagnosis of exclusion
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Dahl M et al: Primary site and other prognostic factors for fibrosarcoma: an analysis of the National Cancer Database. Cureus. 13(10):e19163, 2021
Yoshida A et al: Adult fibrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 122-3, 2020
Hoesly PM et al: Prognostic impact of fibrosarcomatous transformation in dermatofibrosarcoma protuberans: a cohort study. J Am Acad Dermatol. 72(3):419-25, 2015
Verschoor AJ et al: Radiation-induced sarcomas occurring in desmoid-type fibromatosis are not always derived from the primary tumor. Am J Surg Pathol. 39(12):1701-7, 2015
Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 322-8, 2014
Walker EA et al: Magnetic resonance imaging of malignant soft tissue neoplasms in the adult. Radiol Clin North Am. 49(6):1219-34, vi, 2011
Weiss SW et al: Fibrosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 303-10, 2008
Fisher C et al: Adult fibrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 100-1, 2002
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
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TERMINOLOGY
Definitions
Rare sarcoma composed of relatively monomorphic fibroblastic tumor cells with variable collagen production and often herringbone architecture
Pathologic diagnosis of exclusion
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Dahl M et al: Primary site and other prognostic factors for fibrosarcoma: an analysis of the National Cancer Database. Cureus. 13(10):e19163, 2021
Yoshida A et al: Adult fibrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 122-3, 2020
Hoesly PM et al: Prognostic impact of fibrosarcomatous transformation in dermatofibrosarcoma protuberans: a cohort study. J Am Acad Dermatol. 72(3):419-25, 2015
Verschoor AJ et al: Radiation-induced sarcomas occurring in desmoid-type fibromatosis are not always derived from the primary tumor. Am J Surg Pathol. 39(12):1701-7, 2015
Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 322-8, 2014
Walker EA et al: Magnetic resonance imaging of malignant soft tissue neoplasms in the adult. Radiol Clin North Am. 49(6):1219-34, vi, 2011
Weiss SW et al: Fibrosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 303-10, 2008
Fisher C et al: Adult fibrosarcoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 100-1, 2002
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