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Fibrosis/Cirrhosis
Alexander J. Towbin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Cirrhosis: Liver disease characterized by bridging fibrosis

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • CT Findings

              • MR Findings

                • Imaging Recommendations

                  PATHOLOGY

                  • Staging, Grading, & Classification

                    CLINICAL ISSUES

                    • Presentation

                      • Natural History & Prognosis

                        • Treatment

                          Selected References

                          1. Dillman JR et al: Imaging of Fontan-associated liver disease. Pediatr Radiol. 50(11):1528-41, 2020
                          2. Mojtahed A et al: Pearls and pitfalls of metabolic liver magnetic resonance imaging in the pediatric population. Semin Ultrasound CT MR. 41(5):451-61, 2020
                          3. Vittorio J et al: Recent advances in understanding and managing pediatric nonalcoholic fatty liver disease. F1000Res. 9, 2020
                          4. Komatsu H et al: Liver disease secondary to congenital heart disease in children. Expert Rev Gastroenterol Hepatol. 13(7):651-66, 2019
                          5. Nobili V et al: NAFLD in children: new genes, new diagnostic modalities and new drugs. Nat Rev Gastroenterol Hepatol. 16(9):517-30, 2019
                          6. Shen WJ et al: Liver fibrosis in biliary atresia. World J Pediatr. 15(2):117-23, 2019
                          7. Yoon H et al: Quantitative imaging in pediatric hepatobiliary disease. Korean J Radiol. 20(9):1342-57, 2019
                          8. Chapin CA et al: Cirrhosis and portal hypertension in the pediatric population. Clin Liver Dis. 22(4):735-52, 2018
                          9. Serai SD et al: Putting it all together: established and emerging MRI techniques for detecting and measuring liver fibrosis. Pediatr Radiol. 48(9):1256-72, 2018
                          10. Cordova J et al: An overview of cirrhosis in children. Pediatr Ann. 45(12):e427-32, 2016
                          11. Pawluś A et al: Ultrasound elastography--review of techniques and Its clinical applications in pediatrics--part 1. Adv Clin Exp Med. 24(3):537-43, 2015
                          12. Towbin AJ et al: Magnetic resonance imaging of the pediatric liver: imaging of steatosis, iron deposition, and fibrosis. Magn Reson Imaging Clin N Am. 21(4):669-80, 2013
                          Related Anatomy
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Terminology

                            • Imaging

                              • Clinical Issues

                                TERMINOLOGY

                                • Definitions

                                  • Cirrhosis: Liver disease characterized by bridging fibrosis

                                IMAGING

                                • General Features

                                  • Ultrasonographic Findings

                                    • CT Findings

                                      • MR Findings

                                        • Imaging Recommendations

                                          PATHOLOGY

                                          • Staging, Grading, & Classification

                                            CLINICAL ISSUES

                                            • Presentation

                                              • Natural History & Prognosis

                                                • Treatment

                                                  Selected References

                                                  1. Dillman JR et al: Imaging of Fontan-associated liver disease. Pediatr Radiol. 50(11):1528-41, 2020
                                                  2. Mojtahed A et al: Pearls and pitfalls of metabolic liver magnetic resonance imaging in the pediatric population. Semin Ultrasound CT MR. 41(5):451-61, 2020
                                                  3. Vittorio J et al: Recent advances in understanding and managing pediatric nonalcoholic fatty liver disease. F1000Res. 9, 2020
                                                  4. Komatsu H et al: Liver disease secondary to congenital heart disease in children. Expert Rev Gastroenterol Hepatol. 13(7):651-66, 2019
                                                  5. Nobili V et al: NAFLD in children: new genes, new diagnostic modalities and new drugs. Nat Rev Gastroenterol Hepatol. 16(9):517-30, 2019
                                                  6. Shen WJ et al: Liver fibrosis in biliary atresia. World J Pediatr. 15(2):117-23, 2019
                                                  7. Yoon H et al: Quantitative imaging in pediatric hepatobiliary disease. Korean J Radiol. 20(9):1342-57, 2019
                                                  8. Chapin CA et al: Cirrhosis and portal hypertension in the pediatric population. Clin Liver Dis. 22(4):735-52, 2018
                                                  9. Serai SD et al: Putting it all together: established and emerging MRI techniques for detecting and measuring liver fibrosis. Pediatr Radiol. 48(9):1256-72, 2018
                                                  10. Cordova J et al: An overview of cirrhosis in children. Pediatr Ann. 45(12):e427-32, 2016
                                                  11. Pawluś A et al: Ultrasound elastography--review of techniques and Its clinical applications in pediatrics--part 1. Adv Clin Exp Med. 24(3):537-43, 2015
                                                  12. Towbin AJ et al: Magnetic resonance imaging of the pediatric liver: imaging of steatosis, iron deposition, and fibrosis. Magn Reson Imaging Clin N Am. 21(4):669-80, 2013