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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Fibrous dysplasia (FD): Fibrous tissue replaces normal medullary spaces
- Weaker than normal bone
- At risk for pain, pathologic fracture, bone deformity
- Usually incidental finding
- Monostotic (affecting 1 bone) and polyostotic (affecting > 1 bone)
- Fibrous dysplasia (FD): Fibrous tissue replaces normal medullary spaces
IMAGING
General Features
Nuclear Medicine Findings
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kochanowski NE et al: Radiographic diagnosis of fibrous dysplasia in maxilla. Cureus. 10(8):e3127, 2018
- Zhang L et al: The value of 99mTc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia. BMC Med Imaging. 17(1):46, 2017
- Bousson V et al: Fibrous dysplasia and McCune-Albright syndrome: imaging for positive and differential diagnoses, prognosis, and follow-up guidelines. Eur J Radiol. 83(10):1828-42, 2014
- Bloem JL et al: Bone and soft tissue tumors of hip and pelvis. Eur J Radiol. 81(12):3793-801, 2012
- Hsu W et al: Radionuclide imaging in the diagnosis and management of orthopaedic disease. J Am Acad Orthop Surg. 20(3):151-9, 2012
- Sandhu SV et al: Clinicoradiologic perspective of a severe case of polyostotic fibrous dysplasia. J Oral Maxillofac Pathol. 16(2):301-5, 2012
- Zhang Y et al: Multiple metastasis-like bone lesions in scintigraphic imaging. J Biomed Biotechnol. 2012:957364, 2012
- Amit M et al: Fibrous dysplasia of the sphenoid and skull base. Otolaryngol Clin North Am. 44(4):891-902, vii-viii, 2011
- Ihde LL et al: Sclerosing bone dysplasias: review and differentiation from other causes of osteosclerosis. Radiographics. 31(7):1865-82, 2011
- Cook GJ et al: Miscellaneous indications in bone scintigraphy: metabolic bone diseases and malignant bone tumors. Semin Nucl Med. 40(1):52-61, 2010
- Dumitrescu CE et al: McCune-Albright syndrome. Orphanet J Rare Dis. 3:12, 2008
- Leet AI et al: Current approach to fibrous dysplasia of bone and McCune-Albright syndrome. J Child Orthop. 1(1):3-17, 2007
- Fitzpatrick KA et al: Imaging findings of fibrous dysplasia with histopathologic and intraoperative correlation. AJR Am J Roentgenol. 182(6):1389-98, 2004
- Nakahara T et al: Use of bone SPECT in the evaluation of fibrous dysplasia of the skull. Clin Nucl Med. 29(9):554-9, 2004
- Zhibin Y et al: The role of radionuclide bone scintigraphy in fibrous dysplasia of bone. Clin Nucl Med. 29(3):177-80, 2004
- Aoki J et al: FDG PET of primary benign and malignant bone tumors: standardized uptake value in 52 lesions. Radiology. 219(3):774-7, 2001
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Fibrous dysplasia (FD): Fibrous tissue replaces normal medullary spaces
- Weaker than normal bone
- At risk for pain, pathologic fracture, bone deformity
- Usually incidental finding
- Monostotic (affecting 1 bone) and polyostotic (affecting > 1 bone)
- Fibrous dysplasia (FD): Fibrous tissue replaces normal medullary spaces
IMAGING
General Features
Nuclear Medicine Findings
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kochanowski NE et al: Radiographic diagnosis of fibrous dysplasia in maxilla. Cureus. 10(8):e3127, 2018
- Zhang L et al: The value of 99mTc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia. BMC Med Imaging. 17(1):46, 2017
- Bousson V et al: Fibrous dysplasia and McCune-Albright syndrome: imaging for positive and differential diagnoses, prognosis, and follow-up guidelines. Eur J Radiol. 83(10):1828-42, 2014
- Bloem JL et al: Bone and soft tissue tumors of hip and pelvis. Eur J Radiol. 81(12):3793-801, 2012
- Hsu W et al: Radionuclide imaging in the diagnosis and management of orthopaedic disease. J Am Acad Orthop Surg. 20(3):151-9, 2012
- Sandhu SV et al: Clinicoradiologic perspective of a severe case of polyostotic fibrous dysplasia. J Oral Maxillofac Pathol. 16(2):301-5, 2012
- Zhang Y et al: Multiple metastasis-like bone lesions in scintigraphic imaging. J Biomed Biotechnol. 2012:957364, 2012
- Amit M et al: Fibrous dysplasia of the sphenoid and skull base. Otolaryngol Clin North Am. 44(4):891-902, vii-viii, 2011
- Ihde LL et al: Sclerosing bone dysplasias: review and differentiation from other causes of osteosclerosis. Radiographics. 31(7):1865-82, 2011
- Cook GJ et al: Miscellaneous indications in bone scintigraphy: metabolic bone diseases and malignant bone tumors. Semin Nucl Med. 40(1):52-61, 2010
- Dumitrescu CE et al: McCune-Albright syndrome. Orphanet J Rare Dis. 3:12, 2008
- Leet AI et al: Current approach to fibrous dysplasia of bone and McCune-Albright syndrome. J Child Orthop. 1(1):3-17, 2007
- Fitzpatrick KA et al: Imaging findings of fibrous dysplasia with histopathologic and intraoperative correlation. AJR Am J Roentgenol. 182(6):1389-98, 2004
- Nakahara T et al: Use of bone SPECT in the evaluation of fibrous dysplasia of the skull. Clin Nucl Med. 29(9):554-9, 2004
- Zhibin Y et al: The role of radionuclide bone scintigraphy in fibrous dysplasia of bone. Clin Nucl Med. 29(3):177-80, 2004
- Aoki J et al: FDG PET of primary benign and malignant bone tumors: standardized uptake value in 52 lesions. Radiology. 219(3):774-7, 2001
