link
Bookmarks
Fibrous Dysplasia
Kevin R. Moore, MD; Anne G. Osborn, MD, FACR; Miral D. Jhaveri, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
8
0
1

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Fibrous dysplasia (FD)
            • Synonyms

              • Craniofacial fibrous dysplasia (CFD), osteitis fibrosa, osteodystrophy fibrosa
              • McCune-Albright syndrome (MAS): One of most common FD syndromes
              • Jaffe-Lichtenstein dysplasia (monostotic FD)
            • Definitions

              • Congenital disorder characterized by expanding lesions with mixture of fibrous tissue and woven bone
              • Defect in osteoblastic differentiation and maturation
              • One of most common fibroosseous lesions

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Mierzwiński J et al: Different clinical presentation and management of temporal bone fibrous dysplasia in children. World J Surg Oncol. 16(1):5, 2018
                                              2. Wilson M et al: Fibro-osseous lesions of the skull base in the pediatric population. J Neurol Surg B Skull Base. 79(1):31-6, 2018
                                              3. Frisch CD et al: Fibrous dysplasia of the temporal bone: a review of 66 cases. Laryngoscope. 125(6):1438-43, 2015
                                              4. Bowers CA et al: Surgical treatment of craniofacial fibrous dysplasia in adults. Neurosurg Rev. 37(1):47-53, 2014
                                              5. Boyce AM et al: A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 99(11):4133-40, 2014
                                              6. Neelakantan A et al: Benign and malignant diseases of the clivus. Clin Radiol. 69(12):1295-303, 2014
                                              7. Rossi DC et al: Extensive fibrous dysplasia of skull base: case report. Neurol Sci. ePub, 2014
                                              8. Thomsen MD et al: Clinical and radiological observations in a case series of 26 patients with fibrous dysplasia. Calcif Tissue Int. 94(4):384-95, 2014
                                              9. Zhou SH et al: Gene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker. Int J Clin Exp Pathol. 7(12):8532-41, 2014
                                              10. Fattah A et al: Paediatric craniofacial fibrous dysplasia: the Hospital for Sick Children experience and treatment philosophy. J Plast Reconstr Aesthet Surg. 66(10):1346-55, 2013
                                              11. Hanifi B et al: Craniofacial fibrous dysplasia. Clin Imaging. 37(6):1109-15, 2013
                                              12. Pruksakorn P et al: Craniofacial fibrous dysplasia. Intern Med. 49(3):249-50, 2010
                                              13. MacDonald-Jankowski DS: Fibro-osseous lesions of the face and jaws. Clin Radiol. 59(1):11-25, 2004
                                              Related Anatomy
                                              Loading...
                                              Related Differential Diagnoses
                                              Loading...
                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Fibrous dysplasia (FD)
                                                        • Synonyms

                                                          • Craniofacial fibrous dysplasia (CFD), osteitis fibrosa, osteodystrophy fibrosa
                                                          • McCune-Albright syndrome (MAS): One of most common FD syndromes
                                                          • Jaffe-Lichtenstein dysplasia (monostotic FD)
                                                        • Definitions

                                                          • Congenital disorder characterized by expanding lesions with mixture of fibrous tissue and woven bone
                                                          • Defect in osteoblastic differentiation and maturation
                                                          • One of most common fibroosseous lesions

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Mierzwiński J et al: Different clinical presentation and management of temporal bone fibrous dysplasia in children. World J Surg Oncol. 16(1):5, 2018
                                                                                          2. Wilson M et al: Fibro-osseous lesions of the skull base in the pediatric population. J Neurol Surg B Skull Base. 79(1):31-6, 2018
                                                                                          3. Frisch CD et al: Fibrous dysplasia of the temporal bone: a review of 66 cases. Laryngoscope. 125(6):1438-43, 2015
                                                                                          4. Bowers CA et al: Surgical treatment of craniofacial fibrous dysplasia in adults. Neurosurg Rev. 37(1):47-53, 2014
                                                                                          5. Boyce AM et al: A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 99(11):4133-40, 2014
                                                                                          6. Neelakantan A et al: Benign and malignant diseases of the clivus. Clin Radiol. 69(12):1295-303, 2014
                                                                                          7. Rossi DC et al: Extensive fibrous dysplasia of skull base: case report. Neurol Sci. ePub, 2014
                                                                                          8. Thomsen MD et al: Clinical and radiological observations in a case series of 26 patients with fibrous dysplasia. Calcif Tissue Int. 94(4):384-95, 2014
                                                                                          9. Zhou SH et al: Gene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker. Int J Clin Exp Pathol. 7(12):8532-41, 2014
                                                                                          10. Fattah A et al: Paediatric craniofacial fibrous dysplasia: the Hospital for Sick Children experience and treatment philosophy. J Plast Reconstr Aesthet Surg. 66(10):1346-55, 2013
                                                                                          11. Hanifi B et al: Craniofacial fibrous dysplasia. Clin Imaging. 37(6):1109-15, 2013
                                                                                          12. Pruksakorn P et al: Craniofacial fibrous dysplasia. Intern Med. 49(3):249-50, 2010
                                                                                          13. MacDonald-Jankowski DS: Fibro-osseous lesions of the face and jaws. Clin Radiol. 59(1):11-25, 2004