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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Fibrous dysplasia (FD)
Synonyms
- Craniofacial fibrous dysplasia (CFD), osteitis fibrosa, osteodystrophy fibrosa
- McCune-Albright syndrome (MAS): One of most common FD syndromes
- Jaffe-Lichtenstein dysplasia (monostotic FD)
Definitions
- Congenital disorder characterized by expanding lesions with mixture of fibrous tissue and woven bone
- Defect in osteoblastic differentiation and maturation
- One of most common fibroosseous lesions
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Mierzwiński J et al: Different clinical presentation and management of temporal bone fibrous dysplasia in children. World J Surg Oncol. 16(1):5, 2018
- Wilson M et al: Fibro-osseous lesions of the skull base in the pediatric population. J Neurol Surg B Skull Base. 79(1):31-6, 2018
- Frisch CD et al: Fibrous dysplasia of the temporal bone: a review of 66 cases. Laryngoscope. 125(6):1438-43, 2015
- Bowers CA et al: Surgical treatment of craniofacial fibrous dysplasia in adults. Neurosurg Rev. 37(1):47-53, 2014
- Boyce AM et al: A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 99(11):4133-40, 2014
- Neelakantan A et al: Benign and malignant diseases of the clivus. Clin Radiol. 69(12):1295-303, 2014
- Rossi DC et al: Extensive fibrous dysplasia of skull base: case report. Neurol Sci. ePub, 2014
- Thomsen MD et al: Clinical and radiological observations in a case series of 26 patients with fibrous dysplasia. Calcif Tissue Int. 94(4):384-95, 2014
- Zhou SH et al: Gene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker. Int J Clin Exp Pathol. 7(12):8532-41, 2014
- Fattah A et al: Paediatric craniofacial fibrous dysplasia: the Hospital for Sick Children experience and treatment philosophy. J Plast Reconstr Aesthet Surg. 66(10):1346-55, 2013
- Hanifi B et al: Craniofacial fibrous dysplasia. Clin Imaging. 37(6):1109-15, 2013
- Pruksakorn P et al: Craniofacial fibrous dysplasia. Intern Med. 49(3):249-50, 2010
- MacDonald-Jankowski DS: Fibro-osseous lesions of the face and jaws. Clin Radiol. 59(1):11-25, 2004
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Fibrous dysplasia (FD)
Synonyms
- Craniofacial fibrous dysplasia (CFD), osteitis fibrosa, osteodystrophy fibrosa
- McCune-Albright syndrome (MAS): One of most common FD syndromes
- Jaffe-Lichtenstein dysplasia (monostotic FD)
Definitions
- Congenital disorder characterized by expanding lesions with mixture of fibrous tissue and woven bone
- Defect in osteoblastic differentiation and maturation
- One of most common fibroosseous lesions
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Mierzwiński J et al: Different clinical presentation and management of temporal bone fibrous dysplasia in children. World J Surg Oncol. 16(1):5, 2018
- Wilson M et al: Fibro-osseous lesions of the skull base in the pediatric population. J Neurol Surg B Skull Base. 79(1):31-6, 2018
- Frisch CD et al: Fibrous dysplasia of the temporal bone: a review of 66 cases. Laryngoscope. 125(6):1438-43, 2015
- Bowers CA et al: Surgical treatment of craniofacial fibrous dysplasia in adults. Neurosurg Rev. 37(1):47-53, 2014
- Boyce AM et al: A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 99(11):4133-40, 2014
- Neelakantan A et al: Benign and malignant diseases of the clivus. Clin Radiol. 69(12):1295-303, 2014
- Rossi DC et al: Extensive fibrous dysplasia of skull base: case report. Neurol Sci. ePub, 2014
- Thomsen MD et al: Clinical and radiological observations in a case series of 26 patients with fibrous dysplasia. Calcif Tissue Int. 94(4):384-95, 2014
- Zhou SH et al: Gene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker. Int J Clin Exp Pathol. 7(12):8532-41, 2014
- Fattah A et al: Paediatric craniofacial fibrous dysplasia: the Hospital for Sick Children experience and treatment philosophy. J Plast Reconstr Aesthet Surg. 66(10):1346-55, 2013
- Hanifi B et al: Craniofacial fibrous dysplasia. Clin Imaging. 37(6):1109-15, 2013
- Pruksakorn P et al: Craniofacial fibrous dysplasia. Intern Med. 49(3):249-50, 2010
- MacDonald-Jankowski DS: Fibro-osseous lesions of the face and jaws. Clin Radiol. 59(1):11-25, 2004
