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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Flat epithelial atypia (FEA)
Synonyms
Columnar cell change (CCC)/hyperplasia (CCH) with atypia
Columnar alteration with prominent apical snouts and secretions (CAPSS) with atypia
Clinging carcinoma, monomorphous type
Ductal intraepithelial neoplasia (DIN), grade 1A, flat monomorphic type
Atypical cystic lobules
Definitions
Columnar cell lesion with cytologic atypia
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Hugar SB et al: Isolated flat epithelial atypia on core biopsy is associated with a low risk of upgrade at excision. Am J Clin Pathol. In press, 2019
Chan PMY et al: Majority of flat epithelial atypia diagnosed on biopsy do not require surgical excision. Breast. 37:13-17, 2018
Lamb LR et al: Pathologic upgrade rates of high-risk breast lesions on digital two-dimensional vs tomosynthesis mammography. J Am Coll Surg. 226(5):858-867, 2018
Lamb LR et al: Pathologic upgrade rates of high-risk breast lesions on digital two-dimensional vs tomosynthesis mammography. J Am Coll Surg. 226(5):858-867, 2018
McCroskey Z et al: Flat epithelial atypia in directional vacuum-assisted biopsy of breast microcalcifications: surgical excision may not be necessary. Mod Pathol. 31(7):1097-1106, 2018
Ouldamer L et al: All pure flat atypical atypia lesions of the breast diagnosed using percutaneous vacuum-assisted breast biopsy do not need surgical excision. Breast. 40:4-9, 2018
Ouldamer L et al: All pure flat atypical atypia lesions of the breast diagnosed using percutaneous vacuum-assisted breast biopsy do not need surgical excision. Breast. 40:4-9, 2018
Schiaffino S et al: Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy. Br J Radiol. 91(1081):20170484, 2018
Schiaffino S et al: Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy. Br J Radiol. 91(1081):20170484, 2018
Usón Junior PLS et al: Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens. Pathol Oncol Res. 24(1):95-99, 2018
Usón Junior PLS et al: Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens. Pathol Oncol Res. 24(1):95-99, 2018
El Khoury M et al: Is the outcome at surgery different when flat epithelial atypia and lobular neoplasia are found in association at biopsy? Br J Radiol. 90(1072):20160750, 2017
El Khoury M et al: Is the outcome at surgery different when flat epithelial atypia and lobular neoplasia are found in association at biopsy? Br J Radiol. 90(1072):20160750, 2017
Farshid G et al: Contemporary indications for diagnostic open biopsy in women assessed for screen-detected breast lesions: A ten-year, single institution series of 814 consecutive cases. Breast Cancer Res Treat. 162(1):49-58, 2017
Farshid G et al: Contemporary indications for diagnostic open biopsy in women assessed for screen-detected breast lesions: A ten-year, single institution series of 814 consecutive cases. Breast Cancer Res Treat. 162(1):49-58, 2017
Lamb LR et al: Flat Epithelial Atypia: Upgrade Rates and Risk-Stratification Approach to Support Informed Decision Making. J Am Coll Surg. 225(6):696-701, 2017
Lamb LR et al: Flat Epithelial Atypia: Upgrade Rates and Risk-Stratification Approach to Support Informed Decision Making. J Am Coll Surg. 225(6):696-701, 2017
Rudin AV et al: Flat epithelial atypia on core biopsy and upgrade to cancer: A systematic review and meta-analysis. Ann Surg Oncol. 24(12):3549-3558, 2017
Rudin AV et al: Flat epithelial atypia on core biopsy and upgrade to cancer: A systematic review and meta-analysis. Ann Surg Oncol. 24(12):3549-3558, 2017
Samples LS et al: Surgical implications and variability in the use of the flat epithelial atypia diagnosis on breast biopsy specimens. Breast. 34:34-43, 2017
Samples LS et al: Surgical implications and variability in the use of the flat epithelial atypia diagnosis on breast biopsy specimens. Breast. 34:34-43, 2017
Acott AA et al: Flat epithelial atypia on core needle biopsy, must we surgically excise? Am J Surg. 212(6):1211-1213, 2016
Acott AA et al: Flat epithelial atypia on core needle biopsy, must we surgically excise? Am J Surg. 212(6):1211-1213, 2016
Ahn HS et al: Diagnosis of Columnar Cell Lesions and Atypical Ductal Hyperplasia by Ultrasound-Guided Core Biopsy: Findings Associated with Underestimation of Breast Carcinoma. Ultrasound Med Biol. 42(7):1457-63, 2016
Ahn HS et al: Diagnosis of Columnar Cell Lesions and Atypical Ductal Hyperplasia by Ultrasound-Guided Core Biopsy: Findings Associated with Underestimation of Breast Carcinoma. Ultrasound Med Biol. 42(7):1457-63, 2016
Berry JS et al: Analysis of Clinical and Pathologic Factors of Pure, Flat Epithelial Atypia on Core Needle Biopsy to Aid in the Decision of Excision or Observation. J Cancer. 7(1):1-6, 2016
Berry JS et al: Analysis of Clinical and Pathologic Factors of Pure, Flat Epithelial Atypia on Core Needle Biopsy to Aid in the Decision of Excision or Observation. J Cancer. 7(1):1-6, 2016
Calhoun BC et al: Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature. Histopathology. 68(1):138-51, 2016
Calhoun BC et al: Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature. Histopathology. 68(1):138-51, 2016
Mooney KL et al: Upgrade rates of high-risk breast lesions diagnosed on core needle biopsy: a single-institution experience and literature review. Mod Pathol. 29(12):1471-1484, 2016
Mooney KL et al: Upgrade rates of high-risk breast lesions diagnosed on core needle biopsy: a single-institution experience and literature review. Mod Pathol. 29(12):1471-1484, 2016
Rageth CJ et al: First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions). Breast Cancer Res Treat. 159(2):203-13, 2016
Rageth CJ et al: First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions). Breast Cancer Res Treat. 159(2):203-13, 2016
Saladin C et al: Lesions with unclear malignant potential (B3) after minimally invasive breast biopsy: evaluation of vacuum biopsies performed in Switzerland and recommended further management. Acta Radiol. 57(7):815-21, 2016
Saladin C et al: Lesions with unclear malignant potential (B3) after minimally invasive breast biopsy: evaluation of vacuum biopsies performed in Switzerland and recommended further management. Acta Radiol. 57(7):815-21, 2016
Yamashita Y et al: Does flat epithelial atypia have rounder nuclei than columnar cell change/hyperplasia? A morphometric approach to columnar cell lesions of the breast. Virchows Arch. 468(6):663-73, 2016
Yamashita Y et al: Does flat epithelial atypia have rounder nuclei than columnar cell change/hyperplasia? A morphometric approach to columnar cell lesions of the breast. Virchows Arch. 468(6):663-73, 2016
Calhoun BC et al: Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies. Mod Pathol. 28(5):670-6, 2015
Calhoun BC et al: Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies. Mod Pathol. 28(5):670-6, 2015
Cheung YC et al: Assessment of Breast Specimens With or Without Calcifications in Diagnosing Malignant and Atypia for Mammographic Breast Microcalcifications Without Mass: A STARD-Compliant Diagnostic Accuracy Article. Medicine (Baltimore). 94(42):e1832, 2015
Cheung YC et al: Assessment of Breast Specimens With or Without Calcifications in Diagnosing Malignant and Atypia for Mammographic Breast Microcalcifications Without Mass: A STARD-Compliant Diagnostic Accuracy Article. Medicine (Baltimore). 94(42):e1832, 2015
Elif A et al: Columnar cell lesions of the breast: radiological features and histological correlation. Med Ultrason. 17(2):147-54, 2015
Elif A et al: Columnar cell lesions of the breast: radiological features and histological correlation. Med Ultrason. 17(2):147-54, 2015
Maeda I et al: Positive predictive value for malignancy of pure flat epithelial atypia diagnosis by percutaneous needle biopsy of the breast: management of FEA in ultrasonography. Breast Cancer. 22(6):634-40, 2015
Maeda I et al: Positive predictive value for malignancy of pure flat epithelial atypia diagnosis by percutaneous needle biopsy of the breast: management of FEA in ultrasonography. Breast Cancer. 22(6):634-40, 2015
Morrow M et al: Current management of lesions associated with an increased risk of breast cancer. Nat Rev Clin Oncol. 12(4):227-38, 2015
Morrow M et al: Current management of lesions associated with an increased risk of breast cancer. Nat Rev Clin Oncol. 12(4):227-38, 2015
Said SM et al: Flat epithelial atypia and risk of breast cancer: A Mayo cohort study. Cancer. ePub, 2015
Said SM et al: Flat epithelial atypia and risk of breast cancer: A Mayo cohort study. Cancer. ePub, 2015
Yu CC et al: Predictors of underestimation of malignancy after image-guided core needle biopsy diagnosis of flat epithelial atypia or atypical ductal hyperplasia. Breast J. 21(3):224-32, 2015
Yu CC et al: Predictors of underestimation of malignancy after image-guided core needle biopsy diagnosis of flat epithelial atypia or atypical ductal hyperplasia. Breast J. 21(3):224-32, 2015
Dialani V et al: Does isolated flat epithelial atypia on vacuum-assisted breast core biopsy require surgical excision? Breast J. 20(6):606-14, 2014
Dialani V et al: Does isolated flat epithelial atypia on vacuum-assisted breast core biopsy require surgical excision? Breast J. 20(6):606-14, 2014
Gomes DS et al: Inter-observer variability between general pathologists and a specialist in breast pathology in the diagnosis of lobular neoplasia, columnar cell lesions, atypical ductal hyperplasia and ductal carcinoma in situ of the breast. Diagn Pathol. 9:121, 2014
Gomes DS et al: Inter-observer variability between general pathologists and a specialist in breast pathology in the diagnosis of lobular neoplasia, columnar cell lesions, atypical ductal hyperplasia and ductal carcinoma in situ of the breast. Diagn Pathol. 9:121, 2014
Li Z et al: Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer. Hum Pathol. 45(1):104-9, 2014
Li Z et al: Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer. Hum Pathol. 45(1):104-9, 2014
Neal L et al: Diagnosis and management of benign, atypical, and indeterminate breast lesions detected on core needle biopsy. Mayo Clin Proc. 89(4):536-47, 2014
Neal L et al: Diagnosis and management of benign, atypical, and indeterminate breast lesions detected on core needle biopsy. Mayo Clin Proc. 89(4):536-47, 2014
Prowler VL et al: Surgical excision of pure flat epithelial atypia identified on core needle breast biopsy. Breast. 23(4):352-6, 2014
Prowler VL et al: Surgical excision of pure flat epithelial atypia identified on core needle breast biopsy. Breast. 23(4):352-6, 2014
Becker AK et al: Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated? AJR Am J Roentgenol. 200(3):682-8, 2013
Becker AK et al: Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated? AJR Am J Roentgenol. 200(3):682-8, 2013
Ceugnart L et al: Pure flat epithelial atypia: is there a place for routine surgery? Diagn Interv Imaging. 94(9):861-9, 2013
Ceugnart L et al: Pure flat epithelial atypia: is there a place for routine surgery? Diagn Interv Imaging. 94(9):861-9, 2013
Desouki MM et al: Incidental atypical proliferative lesions in reduction mammoplasty specimens: analysis of 2498 cases from 2 tertiary women's health centers. Hum Pathol. 44(9):1877-81, 2013
Desouki MM et al: Incidental atypical proliferative lesions in reduction mammoplasty specimens: analysis of 2498 cases from 2 tertiary women's health centers. Hum Pathol. 44(9):1877-81, 2013
Villa A et al: Flat epithelial atypia: comparison between 9-gauge and 11-gauge devices. Clin Breast Cancer. 13(6):450-4, 2013
Villa A et al: Flat epithelial atypia: comparison between 9-gauge and 11-gauge devices. Clin Breast Cancer. 13(6):450-4, 2013
Georgian-Smith D et al: Variations in physician recommendations for surgery after diagnosis of a high-risk lesion on breast core needle biopsy. AJR Am J Roentgenol. 198(2):256-63, 2012
Georgian-Smith D et al: Variations in physician recommendations for surgery after diagnosis of a high-risk lesion on breast core needle biopsy. AJR Am J Roentgenol. 198(2):256-63, 2012
Heller SL et al: Imaging features and management of high-risk lesions on contrast-enhanced dynamic breast MRI. AJR Am J Roentgenol. 198(2):249-55, 2012
Heller SL et al: Imaging features and management of high-risk lesions on contrast-enhanced dynamic breast MRI. AJR Am J Roentgenol. 198(2):249-55, 2012
Krishnamurthy S et al: Multidisciplinary considerations in the management of high-risk breast lesions. AJR Am J Roentgenol. 198(2):W132-40, 2012
Krishnamurthy S et al: Multidisciplinary considerations in the management of high-risk breast lesions. AJR Am J Roentgenol. 198(2):W132-40, 2012
Crystal P et al: High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: can underestimation be predicted? Eur Radiol. 21(3):582-9, 2011
Crystal P et al: High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: can underestimation be predicted? Eur Radiol. 21(3):582-9, 2011
Lavoué V et al: Pure flat epithelial atypia (DIN 1a) on core needle biopsy: study of 60 biopsies with follow-up surgical excision. Breast Cancer Res Treat. 125(1):121-6, 2011
Lavoué V et al: Pure flat epithelial atypia (DIN 1a) on core needle biopsy: study of 60 biopsies with follow-up surgical excision. Breast Cancer Res Treat. 125(1):121-6, 2011
Rajan S et al: What is the significance of flat epithelial atypia and what are the management implications? J Clin Pathol. 64(11):1001-4, 2011
Rajan S et al: What is the significance of flat epithelial atypia and what are the management implications? J Clin Pathol. 64(11):1001-4, 2011
Solorzano S et al: Flat epithelial atypia of the breast: pathological-radiological correlation. AJR Am J Roentgenol. 197(3):740-6, 2011
Solorzano S et al: Flat epithelial atypia of the breast: pathological-radiological correlation. AJR Am J Roentgenol. 197(3):740-6, 2011
Sudarshan M et al: Flat epithelial atypia of the breast: characteristics and behaviors. Am J Surg. 201(2):245-50, 2011
Sudarshan M et al: Flat epithelial atypia of the breast: characteristics and behaviors. Am J Surg. 201(2):245-50, 2011
Adams AL: Flat epithelia atypia: a review of current concepts. The Open Breast Cancer Journal. 2:90-94, 2010
Adams AL: Flat epithelia atypia: a review of current concepts. The Open Breast Cancer Journal. 2:90-94, 2010
Georgian-Smith D et al: Controversies on the management of high-risk lesions at core biopsy from a radiology/pathology perspective. Radiol Clin North Am. 48(5):999-1012, 2010
Georgian-Smith D et al: Controversies on the management of high-risk lesions at core biopsy from a radiology/pathology perspective. Radiol Clin North Am. 48(5):999-1012, 2010
Moinfar F: Flat ductal intraepithelial neoplasia of the breast: evolution of Azzopardi's "clinging" concept. Semin Diagn Pathol. 27(1):37-48, 2010
Moinfar F: Flat ductal intraepithelial neoplasia of the breast: evolution of Azzopardi's "clinging" concept. Semin Diagn Pathol. 27(1):37-48, 2010
Noske A et al: Flat epithelial atypia is a common subtype of B3 breast lesions and is associated with noninvasive cancer but not with invasive cancer in final excision histology. Hum Pathol. 41(4):522-7, 2010
Noske A et al: Flat epithelial atypia is a common subtype of B3 breast lesions and is associated with noninvasive cancer but not with invasive cancer in final excision histology. Hum Pathol. 41(4):522-7, 2010
Tozaki M et al: Magnetic resonance-guided vacuum-assisted breast biopsy: results in 100 Japanese women. Jpn J Radiol. 28(7):527-33, 2010
Tozaki M et al: Magnetic resonance-guided vacuum-assisted breast biopsy: results in 100 Japanese women. Jpn J Radiol. 28(7):527-33, 2010
Moinfar F. Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept! Arch Pathol Lab Med. 133(6):879-92, 2009
Moinfar F. Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept! Arch Pathol Lab Med. 133(6):879-92, 2009
Brandt SM et al: The "Rosen Triad": tubular carcinoma, lobular carcinoma in situ, and columnar cell lesions. Adv Anat Pathol. 15(3):140-6, 2008
Brandt SM et al: The "Rosen Triad": tubular carcinoma, lobular carcinoma in situ, and columnar cell lesions. Adv Anat Pathol. 15(3):140-6, 2008
Lerwill MF: Flat epithelial atypia of the breast. Arch Pathol Lab Med. 132(4):615-21, 2008
Lerwill MF: Flat epithelial atypia of the breast. Arch Pathol Lab Med. 132(4):615-21, 2008
Collins LC et al: Clinical and pathologic features of ductal carcinoma in situ associated with the presence of flat epithelial atypia: an analysis of 543 patients. Mod Pathol. 20(11):1149-55, 2007
Collins LC et al: Clinical and pathologic features of ductal carcinoma in situ associated with the presence of flat epithelial atypia: an analysis of 543 patients. Mod Pathol. 20(11):1149-55, 2007
Martel M et al: Flat DIN 1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1,751 core biopsies performed over an 8-year period (1992-1999). Virchows Arch. 451(5):883-91, 2007
Martel M et al: Flat DIN 1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1,751 core biopsies performed over an 8-year period (1992-1999). Virchows Arch. 451(5):883-91, 2007
Pandey S et al: Columnar cell lesions of the breast: mammographic findings with histopathologic correlation. Radiographics. 27 Suppl 1:S79-89, 2007
Pandey S et al: Columnar cell lesions of the breast: mammographic findings with histopathologic correlation. Radiographics. 27 Suppl 1:S79-89, 2007
David N et al: [Diagnosis of flat epithelial atypia (FEA) after stereotactic vacuum-assisted biopsy (VAB) of the breast: What is the best management: systematic surgery for all or follow-up?.] J Radiol. 87(11 Pt 1):1671-7, 2006
David N et al: [Diagnosis of flat epithelial atypia (FEA) after stereotactic vacuum-assisted biopsy (VAB) of the breast: What is the best management: systematic surgery for all or follow-up?.] J Radiol. 87(11 Pt 1):1671-7, 2006
Berg WA: Image-guided breast biopsy and management of high-risk lesions. Radiol Clin North Am. 42(5):935-46, vii, 2004
Berg WA: Image-guided breast biopsy and management of high-risk lesions. Radiol Clin North Am. 42(5):935-46, vii, 2004
Bratthauer GL et al: Assessment of lesions coexisting with various grades of ductal intraepithelial neoplasia of the breast. Virchows Arch. 444(4):340-4, 2004
Bratthauer GL et al: Assessment of lesions coexisting with various grades of ductal intraepithelial neoplasia of the breast. Virchows Arch. 444(4):340-4, 2004
Sewell CW: Pathology of high-risk breast lesions and ductal carcinoma in situ. Radiol Clin North Am. 42(5):821-30, v, 2004
Sewell CW: Pathology of high-risk breast lesions and ductal carcinoma in situ. Radiol Clin North Am. 42(5):821-30, v, 2004
Schnitt SJ: The diagnosis and management of pre-invasive breast disease: flat epithelial atypia--classification, pathologic features and clinical significance. Breast Cancer Res. 5(5):263-8, 2003
Schnitt SJ: The diagnosis and management of pre-invasive breast disease: flat epithelial atypia--classification, pathologic features and clinical significance. Breast Cancer Res. 5(5):263-8, 2003
Tavassoli FA et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: IARC Press, 2003
Tavassoli FA et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: IARC Press, 2003
Oyama T et al: Atypical cystic lobule of the breast: an early stage of low-grade ductal carcinoma in-situ. Breast Cancer. 7(4):326-31, 2000
Oyama T et al: Atypical cystic lobule of the breast: an early stage of low-grade ductal carcinoma in-situ. Breast Cancer. 7(4):326-31, 2000
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Flat epithelial atypia (FEA)
Synonyms
Columnar cell change (CCC)/hyperplasia (CCH) with atypia
Columnar alteration with prominent apical snouts and secretions (CAPSS) with atypia
Clinging carcinoma, monomorphous type
Ductal intraepithelial neoplasia (DIN), grade 1A, flat monomorphic type
Atypical cystic lobules
Definitions
Columnar cell lesion with cytologic atypia
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Hugar SB et al: Isolated flat epithelial atypia on core biopsy is associated with a low risk of upgrade at excision. Am J Clin Pathol. In press, 2019
Chan PMY et al: Majority of flat epithelial atypia diagnosed on biopsy do not require surgical excision. Breast. 37:13-17, 2018
Lamb LR et al: Pathologic upgrade rates of high-risk breast lesions on digital two-dimensional vs tomosynthesis mammography. J Am Coll Surg. 226(5):858-867, 2018
Lamb LR et al: Pathologic upgrade rates of high-risk breast lesions on digital two-dimensional vs tomosynthesis mammography. J Am Coll Surg. 226(5):858-867, 2018
McCroskey Z et al: Flat epithelial atypia in directional vacuum-assisted biopsy of breast microcalcifications: surgical excision may not be necessary. Mod Pathol. 31(7):1097-1106, 2018
Ouldamer L et al: All pure flat atypical atypia lesions of the breast diagnosed using percutaneous vacuum-assisted breast biopsy do not need surgical excision. Breast. 40:4-9, 2018
Ouldamer L et al: All pure flat atypical atypia lesions of the breast diagnosed using percutaneous vacuum-assisted breast biopsy do not need surgical excision. Breast. 40:4-9, 2018
Schiaffino S et al: Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy. Br J Radiol. 91(1081):20170484, 2018
Schiaffino S et al: Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy. Br J Radiol. 91(1081):20170484, 2018
Usón Junior PLS et al: Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens. Pathol Oncol Res. 24(1):95-99, 2018
Usón Junior PLS et al: Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens. Pathol Oncol Res. 24(1):95-99, 2018
El Khoury M et al: Is the outcome at surgery different when flat epithelial atypia and lobular neoplasia are found in association at biopsy? Br J Radiol. 90(1072):20160750, 2017
El Khoury M et al: Is the outcome at surgery different when flat epithelial atypia and lobular neoplasia are found in association at biopsy? Br J Radiol. 90(1072):20160750, 2017
Farshid G et al: Contemporary indications for diagnostic open biopsy in women assessed for screen-detected breast lesions: A ten-year, single institution series of 814 consecutive cases. Breast Cancer Res Treat. 162(1):49-58, 2017
Farshid G et al: Contemporary indications for diagnostic open biopsy in women assessed for screen-detected breast lesions: A ten-year, single institution series of 814 consecutive cases. Breast Cancer Res Treat. 162(1):49-58, 2017
Lamb LR et al: Flat Epithelial Atypia: Upgrade Rates and Risk-Stratification Approach to Support Informed Decision Making. J Am Coll Surg. 225(6):696-701, 2017
Lamb LR et al: Flat Epithelial Atypia: Upgrade Rates and Risk-Stratification Approach to Support Informed Decision Making. J Am Coll Surg. 225(6):696-701, 2017
Rudin AV et al: Flat epithelial atypia on core biopsy and upgrade to cancer: A systematic review and meta-analysis. Ann Surg Oncol. 24(12):3549-3558, 2017
Rudin AV et al: Flat epithelial atypia on core biopsy and upgrade to cancer: A systematic review and meta-analysis. Ann Surg Oncol. 24(12):3549-3558, 2017
Samples LS et al: Surgical implications and variability in the use of the flat epithelial atypia diagnosis on breast biopsy specimens. Breast. 34:34-43, 2017
Samples LS et al: Surgical implications and variability in the use of the flat epithelial atypia diagnosis on breast biopsy specimens. Breast. 34:34-43, 2017
Acott AA et al: Flat epithelial atypia on core needle biopsy, must we surgically excise? Am J Surg. 212(6):1211-1213, 2016
Acott AA et al: Flat epithelial atypia on core needle biopsy, must we surgically excise? Am J Surg. 212(6):1211-1213, 2016
Ahn HS et al: Diagnosis of Columnar Cell Lesions and Atypical Ductal Hyperplasia by Ultrasound-Guided Core Biopsy: Findings Associated with Underestimation of Breast Carcinoma. Ultrasound Med Biol. 42(7):1457-63, 2016
Ahn HS et al: Diagnosis of Columnar Cell Lesions and Atypical Ductal Hyperplasia by Ultrasound-Guided Core Biopsy: Findings Associated with Underestimation of Breast Carcinoma. Ultrasound Med Biol. 42(7):1457-63, 2016
Berry JS et al: Analysis of Clinical and Pathologic Factors of Pure, Flat Epithelial Atypia on Core Needle Biopsy to Aid in the Decision of Excision or Observation. J Cancer. 7(1):1-6, 2016
Berry JS et al: Analysis of Clinical and Pathologic Factors of Pure, Flat Epithelial Atypia on Core Needle Biopsy to Aid in the Decision of Excision or Observation. J Cancer. 7(1):1-6, 2016
Calhoun BC et al: Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature. Histopathology. 68(1):138-51, 2016
Calhoun BC et al: Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature. Histopathology. 68(1):138-51, 2016
Mooney KL et al: Upgrade rates of high-risk breast lesions diagnosed on core needle biopsy: a single-institution experience and literature review. Mod Pathol. 29(12):1471-1484, 2016
Mooney KL et al: Upgrade rates of high-risk breast lesions diagnosed on core needle biopsy: a single-institution experience and literature review. Mod Pathol. 29(12):1471-1484, 2016
Rageth CJ et al: First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions). Breast Cancer Res Treat. 159(2):203-13, 2016
Rageth CJ et al: First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions). Breast Cancer Res Treat. 159(2):203-13, 2016
Saladin C et al: Lesions with unclear malignant potential (B3) after minimally invasive breast biopsy: evaluation of vacuum biopsies performed in Switzerland and recommended further management. Acta Radiol. 57(7):815-21, 2016
Saladin C et al: Lesions with unclear malignant potential (B3) after minimally invasive breast biopsy: evaluation of vacuum biopsies performed in Switzerland and recommended further management. Acta Radiol. 57(7):815-21, 2016
Yamashita Y et al: Does flat epithelial atypia have rounder nuclei than columnar cell change/hyperplasia? A morphometric approach to columnar cell lesions of the breast. Virchows Arch. 468(6):663-73, 2016
Yamashita Y et al: Does flat epithelial atypia have rounder nuclei than columnar cell change/hyperplasia? A morphometric approach to columnar cell lesions of the breast. Virchows Arch. 468(6):663-73, 2016
Calhoun BC et al: Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies. Mod Pathol. 28(5):670-6, 2015
Calhoun BC et al: Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies. Mod Pathol. 28(5):670-6, 2015
Cheung YC et al: Assessment of Breast Specimens With or Without Calcifications in Diagnosing Malignant and Atypia for Mammographic Breast Microcalcifications Without Mass: A STARD-Compliant Diagnostic Accuracy Article. Medicine (Baltimore). 94(42):e1832, 2015
Cheung YC et al: Assessment of Breast Specimens With or Without Calcifications in Diagnosing Malignant and Atypia for Mammographic Breast Microcalcifications Without Mass: A STARD-Compliant Diagnostic Accuracy Article. Medicine (Baltimore). 94(42):e1832, 2015
Elif A et al: Columnar cell lesions of the breast: radiological features and histological correlation. Med Ultrason. 17(2):147-54, 2015
Elif A et al: Columnar cell lesions of the breast: radiological features and histological correlation. Med Ultrason. 17(2):147-54, 2015
Maeda I et al: Positive predictive value for malignancy of pure flat epithelial atypia diagnosis by percutaneous needle biopsy of the breast: management of FEA in ultrasonography. Breast Cancer. 22(6):634-40, 2015
Maeda I et al: Positive predictive value for malignancy of pure flat epithelial atypia diagnosis by percutaneous needle biopsy of the breast: management of FEA in ultrasonography. Breast Cancer. 22(6):634-40, 2015
Morrow M et al: Current management of lesions associated with an increased risk of breast cancer. Nat Rev Clin Oncol. 12(4):227-38, 2015
Morrow M et al: Current management of lesions associated with an increased risk of breast cancer. Nat Rev Clin Oncol. 12(4):227-38, 2015
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