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Pediatrics
Diagnosis
Gastrointestinal
Liver Abnormalities
Focal Nodular Hyperplasia
Focal Nodular Hyperplasia
Ethan A. Smith, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Focal nodular hyperplasia (FNH)

          • Definitions

            • Benign epithelial tumor composed of hepatocytes, abnormal bile ducts, & vascular structures
            • 2% of primary hepatic tumors in children

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Image Interpretation Pearls

                                  Selected References

                                  1. van Kessel CS et al: Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI. Abdom Imaging. 38(3):490-501, 2013
                                  2. Smith EA et al: Incidence and etiology of new liver lesions in pediatric patients previously treated for malignancy. AJR Am J Roentgenol. 199(1):186-91, 2012
                                  3. Towbin AJ et al: Focal nodular hyperplasia in children, adolescents, and young adults. Pediatr Radiol. 41(3):341-9, 2011
                                  4. Chung EM et al: From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation part 1. Benign tumors. Radiographics. 30(3):801-26, 2010
                                  5. Das CJ et al: Imaging of paediatric liver tumours with pathological correlation. Clin Radiol. 64(10):1015-25, 2009
                                  6. Jha P et al: Pediatric liver tumors--a pictorial review. Eur Radiol. 19(1):209-19, 2009
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Pathology

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Abbreviations

                                            • Focal nodular hyperplasia (FNH)

                                          • Definitions

                                            • Benign epithelial tumor composed of hepatocytes, abnormal bile ducts, & vascular structures
                                            • 2% of primary hepatic tumors in children

                                          IMAGING

                                          • General Features

                                            • CT Findings

                                              • MR Findings

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Gross Pathologic & Surgical Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Natural History & Prognosis

                                                              • Treatment

                                                                DIAGNOSTIC CHECKLIST

                                                                • Image Interpretation Pearls

                                                                  Selected References

                                                                  1. van Kessel CS et al: Focal nodular hyperplasia: hepatobiliary enhancement patterns on gadoxetic-acid contrast-enhanced MRI. Abdom Imaging. 38(3):490-501, 2013
                                                                  2. Smith EA et al: Incidence and etiology of new liver lesions in pediatric patients previously treated for malignancy. AJR Am J Roentgenol. 199(1):186-91, 2012
                                                                  3. Towbin AJ et al: Focal nodular hyperplasia in children, adolescents, and young adults. Pediatr Radiol. 41(3):341-9, 2011
                                                                  4. Chung EM et al: From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation part 1. Benign tumors. Radiographics. 30(3):801-26, 2010
                                                                  5. Das CJ et al: Imaging of paediatric liver tumours with pathological correlation. Clin Radiol. 64(10):1015-25, 2009
                                                                  6. Jha P et al: Pediatric liver tumors--a pictorial review. Eur Radiol. 19(1):209-19, 2009