Noncaseating, acid-fast negative or fungal infections primarily occurring as opportunistic infections in immunocompromised patients
Involvement of spine and adjacent soft tissue typically secondary to fungal pathogen
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Crete RN et al: Spinal coccidioidomycosis: MR imaging findings in 41 patients. AJNR Am J Neuroradiol. 39(11):2148-53, 2018
Martinez-Del-Campo E et al: Spinal coccidioidomycosis: a current review of diagnosis and management. World Neurosurg. 108:69-75, 2017
Bakhsh WR et al: Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review. J Surg Orthop Adv. 23(3):162-5, 2014
Raj KA et al: A rare case of spontaneous Aspergillus spondylodiscitis with epidural abscess in a 45-year-old immunocompetent female. J Craniovertebr Junction Spine. 4(2):82-4, 2013
B N N et al: Vertebral osteomyelitis with a rare etiology diagnosed by fine-needle aspiration cytology. Diagn Cytopathol. 38(5):360-3, 2010
Asano T et al: Fungal thoracic spondylodiskitis in an immunocompetent 14-year-old girl. J Nippon Med Sch. 76(5):265-7, 2009
de Lucas EM et al: CT-guided fine-needle aspiration in vertebral osteomyelitis: true usefulness of a common practice. Clin Rheumatol. 28(3):315-20, 2009
Garcia-Vidal C et al: Fungal postoperative spondylodiscitis due to Scedosporium prolificans. Spine J. 9(9):e1-7, 2009
Gerlach UA et al: Aspergillus spondylodiscitis after multivisceral transplantation. Ann Transplant. 14(4):52-7, 2009
Cha JG et al: Candida albicans osteomyelitis of the cervical spine. Skeletal Radiol. 37(4):347-50, 2008
Mahiquez M et al: Nonsurgical treatment of lumbosacral blastomycosis involving L2-S1: a case report. Spine (Phila Pa 1976). 33(13):E442-6, 2008
Al-Tawfiq JA et al: Cryptococcus neoformans abscess and osteomyelitis in an immunocompetent patient with tuberculous lymphadenitis. Infection. 35(5):377-82, 2007
Chen F et al: Mucormycosis spondylodiscitis after lumbar disc puncture. Eur Spine J. 15(3):370-6, 2006
Yung BC et al: Aggressive thoracic actinomycosis complicated by vertebral osteomyelitis and epidural abscess leading to spinal cord compression. Spine (Phila Pa 1976). 25(6):745-8, 2000
Hadjipavlou AG et al: Blastomycosis of the lumbar spine: case report and review of the literature, with emphasis on diagnostic laboratory tools and management. Eur Spine J. 7(5):416-21, 1998
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Fungal spondylodiscitis
Definitions
Noncaseating, acid-fast negative or fungal infections primarily occurring as opportunistic infections in immunocompromised patients
Involvement of spine and adjacent soft tissue typically secondary to fungal pathogen
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Crete RN et al: Spinal coccidioidomycosis: MR imaging findings in 41 patients. AJNR Am J Neuroradiol. 39(11):2148-53, 2018
Martinez-Del-Campo E et al: Spinal coccidioidomycosis: a current review of diagnosis and management. World Neurosurg. 108:69-75, 2017
Bakhsh WR et al: Mycobacterium kansasii infection of the spine in a patient with sarcoidosis: a case report and literature review. J Surg Orthop Adv. 23(3):162-5, 2014
Raj KA et al: A rare case of spontaneous Aspergillus spondylodiscitis with epidural abscess in a 45-year-old immunocompetent female. J Craniovertebr Junction Spine. 4(2):82-4, 2013
B N N et al: Vertebral osteomyelitis with a rare etiology diagnosed by fine-needle aspiration cytology. Diagn Cytopathol. 38(5):360-3, 2010
Asano T et al: Fungal thoracic spondylodiskitis in an immunocompetent 14-year-old girl. J Nippon Med Sch. 76(5):265-7, 2009
de Lucas EM et al: CT-guided fine-needle aspiration in vertebral osteomyelitis: true usefulness of a common practice. Clin Rheumatol. 28(3):315-20, 2009
Garcia-Vidal C et al: Fungal postoperative spondylodiscitis due to Scedosporium prolificans. Spine J. 9(9):e1-7, 2009
Gerlach UA et al: Aspergillus spondylodiscitis after multivisceral transplantation. Ann Transplant. 14(4):52-7, 2009
Cha JG et al: Candida albicans osteomyelitis of the cervical spine. Skeletal Radiol. 37(4):347-50, 2008
Mahiquez M et al: Nonsurgical treatment of lumbosacral blastomycosis involving L2-S1: a case report. Spine (Phila Pa 1976). 33(13):E442-6, 2008
Al-Tawfiq JA et al: Cryptococcus neoformans abscess and osteomyelitis in an immunocompetent patient with tuberculous lymphadenitis. Infection. 35(5):377-82, 2007
Chen F et al: Mucormycosis spondylodiscitis after lumbar disc puncture. Eur Spine J. 15(3):370-6, 2006
Yung BC et al: Aggressive thoracic actinomycosis complicated by vertebral osteomyelitis and epidural abscess leading to spinal cord compression. Spine (Phila Pa 1976). 25(6):745-8, 2000
Hadjipavlou AG et al: Blastomycosis of the lumbar spine: case report and review of the literature, with emphasis on diagnostic laboratory tools and management. Eur Spine J. 7(5):416-21, 1998
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