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Gadolinium Deposition
Santhosh Gaddikeri, MDMiral D. Jhaveri, MD, MBA
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Gadolinium-based contrast agents (GBCAs)
              • Dentate nuclei (DN)
              • Globus pallidus (GP)
            • Definitions

              • Gadolinium deposition in deep brain structures, particularly DN and GP in patients with repeated GBCA exposure

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Kang H et al: Gadolinium deposition in deep brain structures: relationship with dose and ionization of linear gadolinium-based contrast agents. AJNR Am J Neuroradiol. 39(9):1597-603, 2018
                                    2. Gulani V et al: Gadolinium deposition in the brain: summary of evidence and recommendations. Lancet Neurol. 16(7):564-70, 2017
                                    3. McDonald RJ et al: Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology. 275(3):772-82, 2015
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Gadolinium-based contrast agents (GBCAs)
                                                • Dentate nuclei (DN)
                                                • Globus pallidus (GP)
                                              • Definitions

                                                • Gadolinium deposition in deep brain structures, particularly DN and GP in patients with repeated GBCA exposure

                                              IMAGING

                                              • General Features

                                                • CT Findings

                                                  • MR Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Kang H et al: Gadolinium deposition in deep brain structures: relationship with dose and ionization of linear gadolinium-based contrast agents. AJNR Am J Neuroradiol. 39(9):1597-603, 2018
                                                                      2. Gulani V et al: Gadolinium deposition in the brain: summary of evidence and recommendations. Lancet Neurol. 16(7):564-70, 2017
                                                                      3. McDonald RJ et al: Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology. 275(3):772-82, 2015