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Gallbladder Metastases and Lymphoma
R. Brooke Jeffrey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Metastatic deposits involving gallbladder (GB) mucosa (melanoma or lung cancer) or intramural masses (lymphoma)

              IMAGING

              • General Features

                • Imaging Recommendations

                  • Radiographic Findings

                    • CT Findings

                      • MR Findings

                        • Ultrasonographic Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Martel JP et al: Melanoma of the gallbladder. Radiographics. 29(1):291-6, 2009
                                                2. Ono A et al: Primary malignant lymphoma of the gallbladder: a case report and literature review. Br J Radiol. 82(973):e15-9, 2009
                                                3. Kato H et al: Primary non-Hodgkin's lymphoma of the gallbladder diagnosed by laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg. 15(6):659-63, 2008
                                                4. Samplaski MK et al: Malignant melanoma of the gallbladder: a report of two cases and review of the literature. J Gastrointest Surg. 12(6):1123-6, 2008
                                                5. Elsayes KM et al: Magnetic resonance imaging of the gallbladder: spectrum of abnormalities. Acta Radiol. 48(5):476-82, 2007
                                                6. Katz SC et al: Surgical management of melanoma of the gallbladder: a report of 13 cases and review of the literature. Am J Surg. 193(4):493-7, 2007
                                                7. Marone U et al: Laparoscopic cholecystectomy for melanoma metastatic to the gallbladder: is it an adequate surgical procedure? Report of a case and review of the literature. World J Surg Oncol. 5:141, 2007
                                                8. Nelms JK et al: Metastatic malignant melanoma of the gallbladder presenting as biliary colic: a case report and review of literature. Am Surg. 73(8):833-5, 2007
                                                9. Takayama Y et al: Metastatic melanoma of the gallbladder. Comput Med Imaging Graph. 31(6):469-71, 2007
                                                10. Doval DC et al: Breast carcinoma with metastasis to the gallbladder: an unusual case report with a short review of literature. Hepatobiliary Pancreat Dis Int. 5(2):305-7, 2006
                                                11. Rea DJ et al: Image of the month. Malignant melanoma of the gallbladder (primary vs secondary). Arch Surg. 139(12):1383-4, 2004
                                                12. Grasso RF et al: Malignant metastatic melanoma of common bile duct: virtual CT cholangioscopy findings. Hepatogastroenterology. 50(53):1333-5, 2003
                                                13. Limani K et al: Metastatic carcinoma of the gallbladder after a renal cell carcinoma. Acta Chir Belg. 103(2):233-4, 2003
                                                14. Medina V et al: Primary biliary tract malignant melanoma: US, CT, and MR findings. Abdom Imaging. 28(6):842-6, 2003
                                                15. Kleinschmidt-DeMasters BK: Dural metastases. A retrospective surgical and autopsy series. Arch Pathol Lab Med. 125(7):880-7, 2001
                                                16. Cellerino P et al: Metastatic melanoma of the gallbladder. Eur J Surg Oncol. 26(8):815-6, 2000
                                                17. De Simone P et al: Gallbladder melanoma mimicking acute acalculous cholecystitis. Surg Endosc. 14(6):593, 2000
                                                18. Garas G et al: Malignant melanoma metastatic to the common bile duct. J Gastroenterol Hepatol. 15(11):1348-51, 2000
                                                19. Dong XD et al: Melanoma of the gallbladder: a review of cases seen at Duke University Medical Center. Cancer. 85(1):32-9, 1999
                                                20. Holloway BJ et al: Ultrasound diagnosis of metastatic melanoma of the gallbladder. Br J Radiol. 70(839):1122-5, 1997
                                                21. Gates J et al: Primary biliary tract malignant melanoma. Abdom Imaging. 21(5):453-5, 1996
                                                22. Friedman EP et al: Primary lymphoma of the gallbladder. Postgrad Med J. 69(813):585-7, 1993
                                                23. Tartar VM et al: Lymphoma in the wall of the bile ducts: radiologic imaging. Gastrointest Radiol. 15(1):53-7, 1990
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Definitions

                                                              • Metastatic deposits involving gallbladder (GB) mucosa (melanoma or lung cancer) or intramural masses (lymphoma)

                                                            IMAGING

                                                            • General Features

                                                              • Imaging Recommendations

                                                                • Radiographic Findings

                                                                  • CT Findings

                                                                    • MR Findings

                                                                      • Ultrasonographic Findings

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Staging, Grading, & Classification

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Martel JP et al: Melanoma of the gallbladder. Radiographics. 29(1):291-6, 2009
                                                                                              2. Ono A et al: Primary malignant lymphoma of the gallbladder: a case report and literature review. Br J Radiol. 82(973):e15-9, 2009
                                                                                              3. Kato H et al: Primary non-Hodgkin's lymphoma of the gallbladder diagnosed by laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg. 15(6):659-63, 2008
                                                                                              4. Samplaski MK et al: Malignant melanoma of the gallbladder: a report of two cases and review of the literature. J Gastrointest Surg. 12(6):1123-6, 2008
                                                                                              5. Elsayes KM et al: Magnetic resonance imaging of the gallbladder: spectrum of abnormalities. Acta Radiol. 48(5):476-82, 2007
                                                                                              6. Katz SC et al: Surgical management of melanoma of the gallbladder: a report of 13 cases and review of the literature. Am J Surg. 193(4):493-7, 2007
                                                                                              7. Marone U et al: Laparoscopic cholecystectomy for melanoma metastatic to the gallbladder: is it an adequate surgical procedure? Report of a case and review of the literature. World J Surg Oncol. 5:141, 2007
                                                                                              8. Nelms JK et al: Metastatic malignant melanoma of the gallbladder presenting as biliary colic: a case report and review of literature. Am Surg. 73(8):833-5, 2007
                                                                                              9. Takayama Y et al: Metastatic melanoma of the gallbladder. Comput Med Imaging Graph. 31(6):469-71, 2007
                                                                                              10. Doval DC et al: Breast carcinoma with metastasis to the gallbladder: an unusual case report with a short review of literature. Hepatobiliary Pancreat Dis Int. 5(2):305-7, 2006
                                                                                              11. Rea DJ et al: Image of the month. Malignant melanoma of the gallbladder (primary vs secondary). Arch Surg. 139(12):1383-4, 2004
                                                                                              12. Grasso RF et al: Malignant metastatic melanoma of common bile duct: virtual CT cholangioscopy findings. Hepatogastroenterology. 50(53):1333-5, 2003
                                                                                              13. Limani K et al: Metastatic carcinoma of the gallbladder after a renal cell carcinoma. Acta Chir Belg. 103(2):233-4, 2003
                                                                                              14. Medina V et al: Primary biliary tract malignant melanoma: US, CT, and MR findings. Abdom Imaging. 28(6):842-6, 2003
                                                                                              15. Kleinschmidt-DeMasters BK: Dural metastases. A retrospective surgical and autopsy series. Arch Pathol Lab Med. 125(7):880-7, 2001
                                                                                              16. Cellerino P et al: Metastatic melanoma of the gallbladder. Eur J Surg Oncol. 26(8):815-6, 2000
                                                                                              17. De Simone P et al: Gallbladder melanoma mimicking acute acalculous cholecystitis. Surg Endosc. 14(6):593, 2000
                                                                                              18. Garas G et al: Malignant melanoma metastatic to the common bile duct. J Gastroenterol Hepatol. 15(11):1348-51, 2000
                                                                                              19. Dong XD et al: Melanoma of the gallbladder: a review of cases seen at Duke University Medical Center. Cancer. 85(1):32-9, 1999
                                                                                              20. Holloway BJ et al: Ultrasound diagnosis of metastatic melanoma of the gallbladder. Br J Radiol. 70(839):1122-5, 1997
                                                                                              21. Gates J et al: Primary biliary tract malignant melanoma. Abdom Imaging. 21(5):453-5, 1996
                                                                                              22. Friedman EP et al: Primary lymphoma of the gallbladder. Postgrad Med J. 69(813):585-7, 1993
                                                                                              23. Tartar VM et al: Lymphoma in the wall of the bile ducts: radiologic imaging. Gastrointest Radiol. 15(1):53-7, 1990