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Gallbladder Polyps
Siva P. Raman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Polypoid or sessile mass protruding from gallbladder (GB) mucosa

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. John S et al: Gallbladder cancer: imaging appearance and pitfalls in diagnosis. Can Assoc Radiol J. 71(4):448-58, 2020
                                        2. Valibouze C et al: The management of gallbladder polyps. J Visc Surg.157(5):410-7, 2020
                                        3. Wiles R et al: Management and follow-up of gallbladder polyps : Joint guidelines between the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery-European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE). Eur Radiol. 27(9):3856-66, 2017
                                        4. Song ER et al: CT differentiation of 1-2-cm gallbladder polyps: benign vs malignant. Abdom Imaging. 39(2):334-41, 2014
                                        5. Wiles R et al: Growth rate and malignant potential of small gallbladder polyps - systematic review of evidence. Surgeon. 12(4):221-6, 2014
                                        6. Donald G et al: Polyp on ultrasound: now what? The association between gallbladder polyps and cancer. Am Surg. 79(10):1005-8, 2013
                                        7. French DG et al: The diagnostic accuracy of transabdominal ultrasonography needs to be considered when managing gallbladder polyps. Surg Endosc. 27(11):4021-5, 2013
                                        8. Sarkut P et al: Gallbladder polyps: factors affecting surgical decision. World J Gastroenterol. 19(28):4526-30, 2013
                                        9. Andrén-Sandberg A: Diagnosis and management of gallbladder polyps. N Am J Med Sci. 4(5):203-11, 2012
                                        10. Lee J et al: Risk stratification of gallbladder polyps (1-2 cm) for surgical intervention with 18F-FDG PET/CT. J Nucl Med. 53(3):353-8, 2012
                                        11. Corwin MT et al: Incidentally detected gallbladder polyps: is follow-up necessary?--Long-term clinical and US analysis of 346 patients. Radiology. 258(1):277-82, 2011
                                        12. Gallahan WC et al: Diagnosis and management of gallbladder polyps. Gastroenterol Clin North Am. 39(2):359-67, x, 2010
                                        13. Cho JH et al: Hypoechoic foci on EUS are simple and strong predictive factors for neoplastic gallbladder polyps. Gastrointest Endosc. 69(7):1244-50, 2009
                                        14. Colecchia A et al: Natural history of small gallbladder polyps is benign: evidence from a clinical and pathogenetic study. Am J Gastroenterol. 104(3):624-9, 2009
                                        15. Dutta U et al: Gallbladder polyps: how to pick up the sinister ones. J Gastroenterol Hepatol. 24(2):175-8, 2009
                                        16. Ito H et al: Polypoid lesions of the gallbladder: diagnosis and followup. J Am Coll Surg. 208(4):570-5, 2009
                                        17. Kim HC et al: Large fibrous polyps of the gallbladder simulating gallbladder carcinoma. J Ultrasound Med. 28(4):537-40, 2009
                                        18. Park JY et al: Long-term follow up of gallbladder polyps. J Gastroenterol Hepatol. 24(2):219-22, 2009
                                        19. Zielinski MD et al: Comparison of surgically resected polypoid lesions of the gallbladder to their pre-operative ultrasound characteristics. J Gastrointest Surg. 13(1):19-25, 2009
                                        20. Choi JH et al: Pre-operative predictive factors for gallbladder cholesterol polyps using conventional diagnostic imaging. World J Gastroenterol. 14(44):6831-4, 2008
                                        21. Furlan A et al: Gallbladder carcinoma update: multimodality imaging evaluation, staging, and treatment options. AJR Am J Roentgenol. 191(5):1440-7, 2008
                                        22. Hennessey D et al: Polypoid lesions of the gallbladder: does size matter?. Ann Surg. 248(6):1110-1, 2008
                                        23. Chattopadhyay D et al: Outcome of gall bladder polypoidal lesions detected by transabdominal ultrasound scanning: a nine year experience. World J Gastroenterol. 11(14):2171-3, 2005
                                        24. Collett JA et al: Gallbladder polyps: prospective study. J Ultrasound Med. 17(4):207-11, 1998
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • Polypoid or sessile mass protruding from gallbladder (GB) mucosa

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • CT Findings

                                                        • Ultrasonographic Findings

                                                          • Nuclear Medicine Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. John S et al: Gallbladder cancer: imaging appearance and pitfalls in diagnosis. Can Assoc Radiol J. 71(4):448-58, 2020
                                                                              2. Valibouze C et al: The management of gallbladder polyps. J Visc Surg.157(5):410-7, 2020
                                                                              3. Wiles R et al: Management and follow-up of gallbladder polyps : Joint guidelines between the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery-European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE). Eur Radiol. 27(9):3856-66, 2017
                                                                              4. Song ER et al: CT differentiation of 1-2-cm gallbladder polyps: benign vs malignant. Abdom Imaging. 39(2):334-41, 2014
                                                                              5. Wiles R et al: Growth rate and malignant potential of small gallbladder polyps - systematic review of evidence. Surgeon. 12(4):221-6, 2014
                                                                              6. Donald G et al: Polyp on ultrasound: now what? The association between gallbladder polyps and cancer. Am Surg. 79(10):1005-8, 2013
                                                                              7. French DG et al: The diagnostic accuracy of transabdominal ultrasonography needs to be considered when managing gallbladder polyps. Surg Endosc. 27(11):4021-5, 2013
                                                                              8. Sarkut P et al: Gallbladder polyps: factors affecting surgical decision. World J Gastroenterol. 19(28):4526-30, 2013
                                                                              9. Andrén-Sandberg A: Diagnosis and management of gallbladder polyps. N Am J Med Sci. 4(5):203-11, 2012
                                                                              10. Lee J et al: Risk stratification of gallbladder polyps (1-2 cm) for surgical intervention with 18F-FDG PET/CT. J Nucl Med. 53(3):353-8, 2012
                                                                              11. Corwin MT et al: Incidentally detected gallbladder polyps: is follow-up necessary?--Long-term clinical and US analysis of 346 patients. Radiology. 258(1):277-82, 2011
                                                                              12. Gallahan WC et al: Diagnosis and management of gallbladder polyps. Gastroenterol Clin North Am. 39(2):359-67, x, 2010
                                                                              13. Cho JH et al: Hypoechoic foci on EUS are simple and strong predictive factors for neoplastic gallbladder polyps. Gastrointest Endosc. 69(7):1244-50, 2009
                                                                              14. Colecchia A et al: Natural history of small gallbladder polyps is benign: evidence from a clinical and pathogenetic study. Am J Gastroenterol. 104(3):624-9, 2009
                                                                              15. Dutta U et al: Gallbladder polyps: how to pick up the sinister ones. J Gastroenterol Hepatol. 24(2):175-8, 2009
                                                                              16. Ito H et al: Polypoid lesions of the gallbladder: diagnosis and followup. J Am Coll Surg. 208(4):570-5, 2009
                                                                              17. Kim HC et al: Large fibrous polyps of the gallbladder simulating gallbladder carcinoma. J Ultrasound Med. 28(4):537-40, 2009
                                                                              18. Park JY et al: Long-term follow up of gallbladder polyps. J Gastroenterol Hepatol. 24(2):219-22, 2009
                                                                              19. Zielinski MD et al: Comparison of surgically resected polypoid lesions of the gallbladder to their pre-operative ultrasound characteristics. J Gastrointest Surg. 13(1):19-25, 2009
                                                                              20. Choi JH et al: Pre-operative predictive factors for gallbladder cholesterol polyps using conventional diagnostic imaging. World J Gastroenterol. 14(44):6831-4, 2008
                                                                              21. Furlan A et al: Gallbladder carcinoma update: multimodality imaging evaluation, staging, and treatment options. AJR Am J Roentgenol. 191(5):1440-7, 2008
                                                                              22. Hennessey D et al: Polypoid lesions of the gallbladder: does size matter?. Ann Surg. 248(6):1110-1, 2008
                                                                              23. Chattopadhyay D et al: Outcome of gall bladder polypoidal lesions detected by transabdominal ultrasound scanning: a nine year experience. World J Gastroenterol. 11(14):2171-3, 2005
                                                                              24. Collett JA et al: Gallbladder polyps: prospective study. J Ultrasound Med. 17(4):207-11, 1998