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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Ganglioglioma (GG)
Definitions
- Slow-growing neuroepithelial tumor composed of neoplastic ganglion & glial cells
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Pekmezci M et al: The genetic landscape of ganglioglioma. Acta Neuropathol Commun. 6(1):47, 2018
- Zaky W et al: Ganglioglioma in children and young adults: single institution experience and review of the literature. J Neurooncol. 139(3):739-47, 2018
- Dudley RW et al: Pediatric low-grade ganglioglioma: epidemiology, treatments, and outcome analysis on 348 children from the surveillance, epidemiology, and end results database. Neurosurgery. 76(3):313-9; discussion 319; quiz 319-20, 2015
- Haydon DH et al: Greater extent of resection improves ganglioglioma recurrence-free survival in children: a volumetric analysis. Neurosurgery. 75(1):37-42, 2014
- Santos MV et al: Approach to cortical dysplasia associated with glial and glioneuronal tumors (FCD type IIIb). Childs Nerv Syst. 30(11):1869-74, 2014
- Consales A et al: Glioneuronal tumors and epilepsy in children: seizure outcome related to lesionectomy. Minerva Pediatr. 65(6):609-16, 2013
- Deling L et al: Intraventricular ganglioglioma prognosis and hydrocephalus: the largest case series and systematic literature review. Acta Neurochir (Wien). 155(7):1253-60, 2013
- Englot DJ et al: Factors associated with seizure freedom in the surgical resection of glioneuronal tumors. Epilepsia. 53(1):51-7, 2012
- Ogiwara H et al: Pediatric epileptogenic gangliogliomas: seizure outcome and surgical results. J Neurosurg Pediatr. 5(3):271-6, 2010
- Karremann M et al: Anaplastic ganglioglioma in children. J Neurooncol. 92(2):157-63, 2009
- Adachi Y et al: Gangliogliomas: characteristic imaging findings and role in the temporal lobe epilepsy. Neuroradiology. 50(10):829-34, 2008
- Majores M et al: Tumor recurrence and malignant progression of gangliogliomas. Cancer. 113(12):3355-63, 2008
- Park YS et al: Factors contributing to resectability and seizure outcomes in 44 patients with ganglioglioma. Clin Neurol Neurosurg. 110(7):667-73, 2008
- Zhang D et al: Intracranial ganglioglioma: clinicopathological and MRI findings in 16 patients. Clin Radiol. 63(1):80-91, 2008
- Law M et al: Conventional MR imaging with simultaneous measurements of cerebral blood volume and vascular permeability in ganglioglioma. Magn Reson Imaging. 22(5):599-606, 2004
- Im SH et al: Intracranial ganglioglioma: preoperative characteristics and oncologic outcome after surgery. J Neurooncol. 59(2):173-83, 2002
- Hayashi Y et al: Malignant transformation of a gangliocytoma/ganglioglioma into a glioblastoma multiforme: a molecular genetic analysis. Case report. J Neurosurg. 95(1):138-42, 2001
- Provenzale JM et al: Comparison of patient age with MR imaging features of gangliogliomas. AJR Am J Roentgenol. 174(3):859-62, 2000
- Matsumoto K et al: Cerebral gangliogliomas: clinical characteristics, CT and MRI. Acta Neurochir (Wien). 141(2):135-41, 1999
- Kincaid PK et al: Cerebral gangliogliomas: preoperative grading using FDG-PET and 201Tl-SPECT. AJNR Am J Neuroradiol. 19(5):801-6, 1998
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Ganglioglioma (GG)
Definitions
- Slow-growing neuroepithelial tumor composed of neoplastic ganglion & glial cells
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Pekmezci M et al: The genetic landscape of ganglioglioma. Acta Neuropathol Commun. 6(1):47, 2018
- Zaky W et al: Ganglioglioma in children and young adults: single institution experience and review of the literature. J Neurooncol. 139(3):739-47, 2018
- Dudley RW et al: Pediatric low-grade ganglioglioma: epidemiology, treatments, and outcome analysis on 348 children from the surveillance, epidemiology, and end results database. Neurosurgery. 76(3):313-9; discussion 319; quiz 319-20, 2015
- Haydon DH et al: Greater extent of resection improves ganglioglioma recurrence-free survival in children: a volumetric analysis. Neurosurgery. 75(1):37-42, 2014
- Santos MV et al: Approach to cortical dysplasia associated with glial and glioneuronal tumors (FCD type IIIb). Childs Nerv Syst. 30(11):1869-74, 2014
- Consales A et al: Glioneuronal tumors and epilepsy in children: seizure outcome related to lesionectomy. Minerva Pediatr. 65(6):609-16, 2013
- Deling L et al: Intraventricular ganglioglioma prognosis and hydrocephalus: the largest case series and systematic literature review. Acta Neurochir (Wien). 155(7):1253-60, 2013
- Englot DJ et al: Factors associated with seizure freedom in the surgical resection of glioneuronal tumors. Epilepsia. 53(1):51-7, 2012
- Ogiwara H et al: Pediatric epileptogenic gangliogliomas: seizure outcome and surgical results. J Neurosurg Pediatr. 5(3):271-6, 2010
- Karremann M et al: Anaplastic ganglioglioma in children. J Neurooncol. 92(2):157-63, 2009
- Adachi Y et al: Gangliogliomas: characteristic imaging findings and role in the temporal lobe epilepsy. Neuroradiology. 50(10):829-34, 2008
- Majores M et al: Tumor recurrence and malignant progression of gangliogliomas. Cancer. 113(12):3355-63, 2008
- Park YS et al: Factors contributing to resectability and seizure outcomes in 44 patients with ganglioglioma. Clin Neurol Neurosurg. 110(7):667-73, 2008
- Zhang D et al: Intracranial ganglioglioma: clinicopathological and MRI findings in 16 patients. Clin Radiol. 63(1):80-91, 2008
- Law M et al: Conventional MR imaging with simultaneous measurements of cerebral blood volume and vascular permeability in ganglioglioma. Magn Reson Imaging. 22(5):599-606, 2004
- Im SH et al: Intracranial ganglioglioma: preoperative characteristics and oncologic outcome after surgery. J Neurooncol. 59(2):173-83, 2002
- Hayashi Y et al: Malignant transformation of a gangliocytoma/ganglioglioma into a glioblastoma multiforme: a molecular genetic analysis. Case report. J Neurosurg. 95(1):138-42, 2001
- Provenzale JM et al: Comparison of patient age with MR imaging features of gangliogliomas. AJR Am J Roentgenol. 174(3):859-62, 2000
- Matsumoto K et al: Cerebral gangliogliomas: clinical characteristics, CT and MRI. Acta Neurochir (Wien). 141(2):135-41, 1999
- Kincaid PK et al: Cerebral gangliogliomas: preoperative grading using FDG-PET and 201Tl-SPECT. AJNR Am J Neuroradiol. 19(5):801-6, 1998
