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Gastric Cancer and Gastrointestinal Stromal Tumor
Paula Vergara-Wentland, MD; Paige Bennett, MD
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KEY FACTS

  • Imaging

    • Clinical Issues

      TERMINOLOGY

      • Definitions

        • Gastric carcinoma
          • Arises from gastric epithelial lining
          • Fundus and cardia (40%), body (30%), antrum (30%)
            • Early gastric carcinoma (EGC)
              • Confined to mucosa &/or submucosa, ± lymph node metastases
            • Advanced gastric carcinoma (AGC)
              • Invades into muscularis propria or beyond
        • Gastrointestinal stromal tumor (GIST)
          • Nonepithelial neoplasm arising from interstitial cells of Cajal
          • Can be benign or malignant, based on tumor size, mitotic index rate, and presence of metastasis
          • Stomach (50-70%), small intestine (25-35%), or anorectum (< 5%); occasionally colon, mesentery or omentum, gallbladder, duodenal ampulla, or appendix

      IMAGING

      • F-18 FDG PET/CT Findings

        • CT Findings

          • MR Findings

            • Imaging Recommendations

              DIFFERENTIAL DIAGNOSIS

                PATHOLOGY

                • General Features

                  CLINICAL ISSUES

                  • Demographics

                    • Natural History & Prognosis

                      • Treatment

                        DIAGNOSTIC CHECKLIST

                        • Consider

                          Selected References

                          1. Miyake KK et al: The predictive value of preoperative 18F-fluorodeoxyglucose PET for postoperative recurrence in patients with localized primary gastrointestinal stromal tumour. Eur Radiol. 26(12):4664-4674, 2016
                          2. Kaneko Y et al: Improving patient selection for 18F-FDG PET scanning in the staging of gastric cancer. J Nucl Med. 56(4):523-9, 2015
                          3. Hallinan JT et al: Gastric carcinoma: imaging diagnosis, staging and assessment of treatment response. Cancer Imaging. 13:212-27, 2013
                          Related Anatomy
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                          Related Differential Diagnoses
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Imaging

                            • Clinical Issues

                              TERMINOLOGY

                              • Definitions

                                • Gastric carcinoma
                                  • Arises from gastric epithelial lining
                                  • Fundus and cardia (40%), body (30%), antrum (30%)
                                    • Early gastric carcinoma (EGC)
                                      • Confined to mucosa &/or submucosa, ± lymph node metastases
                                    • Advanced gastric carcinoma (AGC)
                                      • Invades into muscularis propria or beyond
                                • Gastrointestinal stromal tumor (GIST)
                                  • Nonepithelial neoplasm arising from interstitial cells of Cajal
                                  • Can be benign or malignant, based on tumor size, mitotic index rate, and presence of metastasis
                                  • Stomach (50-70%), small intestine (25-35%), or anorectum (< 5%); occasionally colon, mesentery or omentum, gallbladder, duodenal ampulla, or appendix

                              IMAGING

                              • F-18 FDG PET/CT Findings

                                • CT Findings

                                  • MR Findings

                                    • Imaging Recommendations

                                      DIFFERENTIAL DIAGNOSIS

                                        PATHOLOGY

                                        • General Features

                                          CLINICAL ISSUES

                                          • Demographics

                                            • Natural History & Prognosis

                                              • Treatment

                                                DIAGNOSTIC CHECKLIST

                                                • Consider

                                                  Selected References

                                                  1. Miyake KK et al: The predictive value of preoperative 18F-fluorodeoxyglucose PET for postoperative recurrence in patients with localized primary gastrointestinal stromal tumour. Eur Radiol. 26(12):4664-4674, 2016
                                                  2. Kaneko Y et al: Improving patient selection for 18F-FDG PET scanning in the staging of gastric cancer. J Nucl Med. 56(4):523-9, 2015
                                                  3. Hallinan JT et al: Gastric carcinoma: imaging diagnosis, staging and assessment of treatment response. Cancer Imaging. 13:212-27, 2013