Nonepithelial; arises from interstitial cells of Cajal
Most common mesenchymal neoplasm of GI tract
GISTs are potentially malignant
Lesions are stratified according to relative risk of recurrence and metastasis
Prediction of aggressive behavior (malignancy) is based on tumor size, site, mitotic rate (MR), and presence of metastasis
Pediatric GIST: Rare; have distinct clinical and pathologic features
Other gastric cancers: Gastric lymphoma (5%), carcinoid
IMAGING
General Features
Nuclear Medicine Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Findlay JM et al: Routinely staging gastric cancer with 18F-FDG PET-CT detects additional metastases and predicts early recurrence and death after surgery. Eur Radiol. 29(5):2490-8, 2019
Kwon Y et al: Preoperative assessment of malignant potential of gastrointestinal stromal tumor by dual-time-point 18F-fluorodeoxyglucose positron emission tomography imaging: usefulness of standardized uptake value and retention index. J Cancer Res Ther. 15(1):142-7, 2019
Yoon JK et al: Clinicopathologic parameters associated with the FDG-avidity in staging of early gastric cancer using 18F-FDG PET. Medicine (Baltimore). 98(31):e16690, 2019
Zhang S et al: Gastric ulcer mimicking malignancy on FDG PET/CT. Clin Nucl Med. 44(2):142-4, 2019
Kaneko Y et al: Improving patient selection for 18F-FDG PET scanning in the staging of gastric cancer. J Nucl Med. 56(4):523-9, 2015
Gastrointestinal stromal tumor. In Edge et al. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer. 175, 2010
Kochhar R et al: Imaging in gastrointestinal stromal tumours: current status and future directions. Clin Radiol. 65(8):584-92, 2010
O'Sullivan PJ et al: The imaging features of gastrointestinal stromal tumours. Eur J Radiol. 60(3):431-8, 2006
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Diagnostic Checklist
TERMINOLOGY
Definitions
Gastric carcinoma (GC)
Malignancy originating from glandular epithelium (adenocarcinoma) of gastric mucosa
Nonepithelial; arises from interstitial cells of Cajal
Most common mesenchymal neoplasm of GI tract
GISTs are potentially malignant
Lesions are stratified according to relative risk of recurrence and metastasis
Prediction of aggressive behavior (malignancy) is based on tumor size, site, mitotic rate (MR), and presence of metastasis
Pediatric GIST: Rare; have distinct clinical and pathologic features
Other gastric cancers: Gastric lymphoma (5%), carcinoid
IMAGING
General Features
Nuclear Medicine Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Findlay JM et al: Routinely staging gastric cancer with 18F-FDG PET-CT detects additional metastases and predicts early recurrence and death after surgery. Eur Radiol. 29(5):2490-8, 2019
Kwon Y et al: Preoperative assessment of malignant potential of gastrointestinal stromal tumor by dual-time-point 18F-fluorodeoxyglucose positron emission tomography imaging: usefulness of standardized uptake value and retention index. J Cancer Res Ther. 15(1):142-7, 2019
Yoon JK et al: Clinicopathologic parameters associated with the FDG-avidity in staging of early gastric cancer using 18F-FDG PET. Medicine (Baltimore). 98(31):e16690, 2019
Zhang S et al: Gastric ulcer mimicking malignancy on FDG PET/CT. Clin Nucl Med. 44(2):142-4, 2019
Kaneko Y et al: Improving patient selection for 18F-FDG PET scanning in the staging of gastric cancer. J Nucl Med. 56(4):523-9, 2015
Gastrointestinal stromal tumor. In Edge et al. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer. 175, 2010
Kochhar R et al: Imaging in gastrointestinal stromal tumours: current status and future directions. Clin Radiol. 65(8):584-92, 2010
O'Sullivan PJ et al: The imaging features of gastrointestinal stromal tumours. Eur J Radiol. 60(3):431-8, 2006
STATdx includes over 200,000 searchable images, including x-ray, CT, MR, and ultrasound images. To access all images, please log in or subscribe.