Michael P. Federle, MD, FACR; R. Brooke Jeffrey, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
13
1
10
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Gastrointestinal stromal tumor (GIST)
Definitions
Submucosal tumor of gastrointestinal (GI) tract derived from interstitial cells of Cajal
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Corless CL et al: Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. J Clin Oncol. 32(15):1563-70, 2014
Tap WD et al: That's the "GIST" of it: use of adjuvant imatinib after resection of a primary GI stromal tumor. J Clin Oncol. 32(15):1543-6, 2014
De Vogelaere K et al: Gastrointestinal stromal tumor of the stomach: progresses in diagnosis and treatment. Acta Gastroenterol Belg. 76(4):403-6, 2013
Holdsworth CH et al: CT and PET: early prognostic indicators of response to imatinib mesylate in patients with gastrointestinal stromal tumor. AJR Am J Roentgenol. 189(6):W324-30, 2007
Lassau N et al: Gastrointestinal stromal tumors treated with imatinib: monitoring response with contrast-enhanced sonography. AJR Am J Roentgenol. 187(5):1267-73, 2006
Warakaulle DR et al: MDCT appearance of gastrointestinal stromal tumors after therapy with imatinib mesylate. AJR Am J Roentgenol. 186(2):510-5, 2006
Antoch G et al: Comparison of PET, CT, and dual-modality PET/CT imaging for monitoring of imatinib (STI571) therapy in patients with gastrointestinal stromal tumors. J Nucl Med. 45(3):357-65, 2004
Gayed I et al: The role of 18F-FDG PET in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors. J Nucl Med. 45(1):17-21, 2004
Haider N et al: Gastric stromal tumors in children. Pediatr Blood Cancer. 42(2):186-9, 2004
Logrono R et al: Recent advances in cell biology, diagnosis, and therapy of gastrointestinal stromal tumor (GIST). Cancer Biol Ther. 3(3)251-8, 2004
Bechtold RE et al: Cystic changes in hepatic and peritoneal metastases from gastrointestinal stromal tumors treated with Gleevec. Abdom Imaging. 28(6):808-14, 2003
Besana-Ciani I et al: Outcome and long term results of surgical resection for gastrointestinal stromal tumors (GIST). Scand J Surg. 92(3):195-9, 2003
Burkill GJ et al: Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology. 226(2):527-32, 2003
Connolly EM et al: Gastrointestinal stromal tumours. Br J Surg. 90(10):1178-86, 2003
Dong Q et al: Epithelioid variant of gastrointestinal stromal tumor: Diagnosis by fine-needle aspiration. Diagn Cytopathol. 29(2):55-60, 2003
Duffaud F et al: Gastrointestinal stromal tumors: biology and treatment. Oncology. 65(3):187-97, 2003
Frolov A et al: Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors. Mol Cancer Ther. 2(8):699-709, 2003
Ghanem N et al: Computed tomography in gastrointestinal stromal tumors. Eur Radiol. 13(7):1669-78, 2003
Kinoshita K et al: Endoscopic ultrasonography-guided fine needle aspiration biopsy in follow-up patients with gastrointestinal stromal tumours. Eur J Gastroenterol Hepatol. 15(11):1189-93, 2003
Lin SC et al: Clinical manifestations and prognostic factors in patients with gastrointestinal stromal tumors. World J Gastroenterol. 9(12):2809-12, 2003
Reddy MP et al: F-18 FDG PET imaging in gastrointestinal stromal tumor. Clin Nucl Med. 28(8):677-9, 2003
Rosai J: GIST: an update. Int J Surg Pathol. 11(3):177-86, 2003
Rossi CR et al: Gastrointestinal stromal tumors: from a surgical to a molecular approach. Int J Cancer. 107(2):171-6, 2003
Tateishi U et al: Gastrointestinal stromal tumor. Correlation of computed tomography findings with tumor grade and mortality. J Comput Assist Tomogr. 27(5):792-8, 2003
Wong NA et al: Prognostic indicators for gastrointestinal stromal tumours: a clinicopathological and immunohistochemical study of 108 resected cases of the stomach. Histopathology. 43(2):118-26, 2003
Wu PC et al: Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) era. Surgery. 134(4):656-65; discussion 665-6, 2003
Belloni M et al: Endoscopic ultrasound and Computed Tomography in gastric stromal tumours. Radiol Med (Torino). 103(1-2):65-73, 2002
Miettinen M et al: Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol. 33(5):478-83, 2002
Kim CJ et al: Gastrointestinal stromal tumors: analysis of clinical and pathologic factors. Am Surg. 67(2):135-7, 2001
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Gastrointestinal stromal tumor (GIST)
Definitions
Submucosal tumor of gastrointestinal (GI) tract derived from interstitial cells of Cajal
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Corless CL et al: Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. J Clin Oncol. 32(15):1563-70, 2014
Tap WD et al: That's the "GIST" of it: use of adjuvant imatinib after resection of a primary GI stromal tumor. J Clin Oncol. 32(15):1543-6, 2014
De Vogelaere K et al: Gastrointestinal stromal tumor of the stomach: progresses in diagnosis and treatment. Acta Gastroenterol Belg. 76(4):403-6, 2013
Holdsworth CH et al: CT and PET: early prognostic indicators of response to imatinib mesylate in patients with gastrointestinal stromal tumor. AJR Am J Roentgenol. 189(6):W324-30, 2007
Lassau N et al: Gastrointestinal stromal tumors treated with imatinib: monitoring response with contrast-enhanced sonography. AJR Am J Roentgenol. 187(5):1267-73, 2006
Warakaulle DR et al: MDCT appearance of gastrointestinal stromal tumors after therapy with imatinib mesylate. AJR Am J Roentgenol. 186(2):510-5, 2006
Antoch G et al: Comparison of PET, CT, and dual-modality PET/CT imaging for monitoring of imatinib (STI571) therapy in patients with gastrointestinal stromal tumors. J Nucl Med. 45(3):357-65, 2004
Gayed I et al: The role of 18F-FDG PET in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors. J Nucl Med. 45(1):17-21, 2004
Haider N et al: Gastric stromal tumors in children. Pediatr Blood Cancer. 42(2):186-9, 2004
Logrono R et al: Recent advances in cell biology, diagnosis, and therapy of gastrointestinal stromal tumor (GIST). Cancer Biol Ther. 3(3)251-8, 2004
Bechtold RE et al: Cystic changes in hepatic and peritoneal metastases from gastrointestinal stromal tumors treated with Gleevec. Abdom Imaging. 28(6):808-14, 2003
Besana-Ciani I et al: Outcome and long term results of surgical resection for gastrointestinal stromal tumors (GIST). Scand J Surg. 92(3):195-9, 2003
Burkill GJ et al: Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology. 226(2):527-32, 2003
Connolly EM et al: Gastrointestinal stromal tumours. Br J Surg. 90(10):1178-86, 2003
Dong Q et al: Epithelioid variant of gastrointestinal stromal tumor: Diagnosis by fine-needle aspiration. Diagn Cytopathol. 29(2):55-60, 2003
Duffaud F et al: Gastrointestinal stromal tumors: biology and treatment. Oncology. 65(3):187-97, 2003
Frolov A et al: Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors. Mol Cancer Ther. 2(8):699-709, 2003
Ghanem N et al: Computed tomography in gastrointestinal stromal tumors. Eur Radiol. 13(7):1669-78, 2003
Kinoshita K et al: Endoscopic ultrasonography-guided fine needle aspiration biopsy in follow-up patients with gastrointestinal stromal tumours. Eur J Gastroenterol Hepatol. 15(11):1189-93, 2003
Lin SC et al: Clinical manifestations and prognostic factors in patients with gastrointestinal stromal tumors. World J Gastroenterol. 9(12):2809-12, 2003
Reddy MP et al: F-18 FDG PET imaging in gastrointestinal stromal tumor. Clin Nucl Med. 28(8):677-9, 2003
Rosai J: GIST: an update. Int J Surg Pathol. 11(3):177-86, 2003
Rossi CR et al: Gastrointestinal stromal tumors: from a surgical to a molecular approach. Int J Cancer. 107(2):171-6, 2003
Tateishi U et al: Gastrointestinal stromal tumor. Correlation of computed tomography findings with tumor grade and mortality. J Comput Assist Tomogr. 27(5):792-8, 2003
Wong NA et al: Prognostic indicators for gastrointestinal stromal tumours: a clinicopathological and immunohistochemical study of 108 resected cases of the stomach. Histopathology. 43(2):118-26, 2003
Wu PC et al: Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) era. Surgery. 134(4):656-65; discussion 665-6, 2003
Belloni M et al: Endoscopic ultrasound and Computed Tomography in gastric stromal tumours. Radiol Med (Torino). 103(1-2):65-73, 2002
Miettinen M et al: Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol. 33(5):478-83, 2002
Kim CJ et al: Gastrointestinal stromal tumors: analysis of clinical and pathologic factors. Am Surg. 67(2):135-7, 2001
STATdx includes over 200,000 searchable images, including x-ray, CT, MR and ultrasound images. To access all images, please log in or subscribe.