Submucosal tumor of gastrointestinal (GI) tract derived from interstitial cells of Cajal
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Mazer L et al: Minimally invasive options for gastrointestinal stromal tumors of the stomach. Surg Endosc. 35(3):1324-30, 2021
Akin EA et al: Clinical impact of FDG PET/CT in alimentary tract malignancies: an updated review. Abdom Radiol (NY). 45(4):1018-35, 2020
Bajaj G et al: Comprehensive review of abdominopelvic mesenchymal tumors with radiologic pathologic correlation and update on current treatment guidelines-part 2. Semin Ultrasound CT MR. 41(2):239-59, 2020
Burch J et al: Cancer, gastrointestinal stromal (GIST). StatPearls, 2020
Wang J et al: Value of CT imaging in the differentiation of gastric leiomyoma from gastric stromal tumor. Can Assoc Radiol J. 846537119885671, 2020
Danti G et al: Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST). Acta Biomed. 90(5-S):9-19, 2019
Ogun GO et al: Gastrointestinal stromal tumours (GIST): a review of cases from Nigeria. J Gastrointest Cancer. 51(3):729-37, 2019
Parab TM et al: Gastrointestinal stromal tumors: a comprehensive review. J Gastrointest Oncol. 10(1):144-54, 2019
Sharma NR et al: Gastric gastrointestinal stromal tumors (GIST): a case series and current state of the art in the workup and treatment of this rare disease. J Gastrointest Cancer. 50(3):548-55, 2019
Theiss L et al: Gastrointestinal stromal tumors of the stomach and esophagus. Surg Clin North Am. 99(3):543-53, 2019
Waidhauser J et al: Frequency, localization, and types of gastrointestinal stromal tumor-associated neoplasia. World J Gastroenterol. 25(30):4261-77, 2019
Yang Z et al: Clinicopathological features and prognosis of 276 cases of primary small (≤ 2 cm) gastric gastrointestinal stromal tumors: a multicenter data review. Surg Endosc. 33(9):2982-90, 2019
Al Momani LA et al: Recurrent gastric gastrointestinal stromal tumor in a patient with neurofibromatosis. Cureus. 10(6):e2854, 2018
Salati M et al: Heavily calcified gastrointestinal stromal tumors: pathophysiology and implications of a rare clinicopathologic entity. World J Gastrointest Oncol. 9(3):135-41, 2017
Søreide K et al: Global epidemiology of gastrointestinal stromal tumours (GIST): a systematic review of population-based cohort studies. Cancer Epidemiol. 40:39-46, 2016
Yang HK et al: Leiomyomas in the gastric cardia: CT findings and differentiation from gastrointestinal stromal tumors. Eur J Radiol. 84(9):1694-700, 2015
Tap WD et al: That's the "GIST" of it: use of adjuvant imatinib after resection of a primary GI stromal tumor. J Clin Oncol. 32(15):1543-6, 2014
Tirumani SH et al: MDCT features of succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumours. Br J Radiol. 87(1043):20140476, 2014
Ba-Ssalamah A et al: Texture-based classification of different gastric tumors at contrast-enhanced CT. Eur J Radiol. 82(10):e537-43, 2013
De Vogelaere K et al: Gastrointestinal stromal tumor of the stomach: progresses in diagnosis and treatment. Acta Gastroenterol Belg. 76(4):403-6, 2013
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Gastrointestinal stromal tumor (GIST)
Definitions
Submucosal tumor of gastrointestinal (GI) tract derived from interstitial cells of Cajal
IMAGING
General Features
Fluoroscopic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Mazer L et al: Minimally invasive options for gastrointestinal stromal tumors of the stomach. Surg Endosc. 35(3):1324-30, 2021
Akin EA et al: Clinical impact of FDG PET/CT in alimentary tract malignancies: an updated review. Abdom Radiol (NY). 45(4):1018-35, 2020
Bajaj G et al: Comprehensive review of abdominopelvic mesenchymal tumors with radiologic pathologic correlation and update on current treatment guidelines-part 2. Semin Ultrasound CT MR. 41(2):239-59, 2020
Burch J et al: Cancer, gastrointestinal stromal (GIST). StatPearls, 2020
Wang J et al: Value of CT imaging in the differentiation of gastric leiomyoma from gastric stromal tumor. Can Assoc Radiol J. 846537119885671, 2020
Danti G et al: Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST). Acta Biomed. 90(5-S):9-19, 2019
Ogun GO et al: Gastrointestinal stromal tumours (GIST): a review of cases from Nigeria. J Gastrointest Cancer. 51(3):729-37, 2019
Parab TM et al: Gastrointestinal stromal tumors: a comprehensive review. J Gastrointest Oncol. 10(1):144-54, 2019
Sharma NR et al: Gastric gastrointestinal stromal tumors (GIST): a case series and current state of the art in the workup and treatment of this rare disease. J Gastrointest Cancer. 50(3):548-55, 2019
Theiss L et al: Gastrointestinal stromal tumors of the stomach and esophagus. Surg Clin North Am. 99(3):543-53, 2019
Waidhauser J et al: Frequency, localization, and types of gastrointestinal stromal tumor-associated neoplasia. World J Gastroenterol. 25(30):4261-77, 2019
Yang Z et al: Clinicopathological features and prognosis of 276 cases of primary small (≤ 2 cm) gastric gastrointestinal stromal tumors: a multicenter data review. Surg Endosc. 33(9):2982-90, 2019
Al Momani LA et al: Recurrent gastric gastrointestinal stromal tumor in a patient with neurofibromatosis. Cureus. 10(6):e2854, 2018
Salati M et al: Heavily calcified gastrointestinal stromal tumors: pathophysiology and implications of a rare clinicopathologic entity. World J Gastrointest Oncol. 9(3):135-41, 2017
Søreide K et al: Global epidemiology of gastrointestinal stromal tumours (GIST): a systematic review of population-based cohort studies. Cancer Epidemiol. 40:39-46, 2016
Yang HK et al: Leiomyomas in the gastric cardia: CT findings and differentiation from gastrointestinal stromal tumors. Eur J Radiol. 84(9):1694-700, 2015
Tap WD et al: That's the "GIST" of it: use of adjuvant imatinib after resection of a primary GI stromal tumor. J Clin Oncol. 32(15):1543-6, 2014
Tirumani SH et al: MDCT features of succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumours. Br J Radiol. 87(1043):20140476, 2014
Ba-Ssalamah A et al: Texture-based classification of different gastric tumors at contrast-enhanced CT. Eur J Radiol. 82(10):e537-43, 2013
De Vogelaere K et al: Gastrointestinal stromal tumor of the stomach: progresses in diagnosis and treatment. Acta Gastroenterol Belg. 76(4):403-6, 2013
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