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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Primary uterine, vaginal, or vulvar lymphoma
Extranodal non-Hodgkin lymphoma (NHL), of genital tract
Either uterus (including cervix &/or corpus), vagina, or vulva
Secondary uterine lymphoma
Genital involvement is part of a generalized process (40-50% of patients with lymphoma at autopsy), cervix, vagina, or vulva
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Alves Viera MA et al: Primary lymphomas of the female genital tract: imaging findings. Diagn Interv Radiol. 20(2):110-5, 2014
Merritt AJ et al: Primary extranodal marginal zone B cell lymphoma of the uterus: a case study and review of the literature. J Clin Pathol. 67(4):375-7, 2014
Salem U et al: Hematopoietic tumors of the female genital system: imaging features with pathologic correlation. Abdom Imaging. Epub ahead of print, 2014
Hashimoto A et al: [Primary diffuse large B-cell lymphoma of the uterine cervix successfully treated with rituximabplus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy-a case report.] Gan To Kagaku Ryoho. 40(13):2589-92, 2013
Isosaka M et al: [Primary diffuse large B-cell lymphoma of the uterus complicated with hydronephrosis.] Rinsho Ketsueki. 54(4):392-6, 2013
Onyiuke I et al: Primary gynecologic lymphoma: imaging findings. AJR Am J Roentgenol. 201(4):W648-55, 2013
Ragupathy K et al: Primary vaginal non-Hodgkin lymphoma: gynecologic diagnosis of a hematologic malignancy. J Low Genit Tract Dis. 17(3):326-9, 2013
Sugimoto KJ et al: Diffuse large B-cell lymphoma of the uterus suspected of having transformed from a marginal zone B-cell lymphoma harboring trisomy 18: a case report and review of the literature. Int J Clin Exp Pathol. 6(12):2979-88, 2013
Sohaib SA et al: Imaging of uterine malignancies. Semin Ultrasound CT MR. 31(5):377-87, 2010
Goto N et al: Magnetic resonance findings of primary uterine malignant lymphoma. Magn Reson Med Sci. 6(1):7-13, 2007
Niwa K et al: Primary lymphoma of the uterine corpus: an unusual location for a common disease--case report. Eur J Gynaecol Oncol. 28(6):522-3, 2007
Hamadani M et al: Marginal zone B-cell lymphoma of the uterus: a case report and review of the literature. J Okla State Med Assoc. 99(4):154-6, 2006
Keller C et al: Primary Burkitt lymphoma of the uterine corpus. Leuk Lymphoma. 47(1):141-5, 2006
Lagoo AS et al: Lymphoma of the female genital tract: current status. Int J Gynecol Pathol. 25(1):1-21, 2006
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Primary uterine, vaginal, or vulvar lymphoma
Extranodal non-Hodgkin lymphoma (NHL), of genital tract
Either uterus (including cervix &/or corpus), vagina, or vulva
Secondary uterine lymphoma
Genital involvement is part of a generalized process (40-50% of patients with lymphoma at autopsy), cervix, vagina, or vulva
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Alves Viera MA et al: Primary lymphomas of the female genital tract: imaging findings. Diagn Interv Radiol. 20(2):110-5, 2014
Merritt AJ et al: Primary extranodal marginal zone B cell lymphoma of the uterus: a case study and review of the literature. J Clin Pathol. 67(4):375-7, 2014
Salem U et al: Hematopoietic tumors of the female genital system: imaging features with pathologic correlation. Abdom Imaging. Epub ahead of print, 2014
Hashimoto A et al: [Primary diffuse large B-cell lymphoma of the uterine cervix successfully treated with rituximabplus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy-a case report.] Gan To Kagaku Ryoho. 40(13):2589-92, 2013
Isosaka M et al: [Primary diffuse large B-cell lymphoma of the uterus complicated with hydronephrosis.] Rinsho Ketsueki. 54(4):392-6, 2013
Onyiuke I et al: Primary gynecologic lymphoma: imaging findings. AJR Am J Roentgenol. 201(4):W648-55, 2013
Ragupathy K et al: Primary vaginal non-Hodgkin lymphoma: gynecologic diagnosis of a hematologic malignancy. J Low Genit Tract Dis. 17(3):326-9, 2013
Sugimoto KJ et al: Diffuse large B-cell lymphoma of the uterus suspected of having transformed from a marginal zone B-cell lymphoma harboring trisomy 18: a case report and review of the literature. Int J Clin Exp Pathol. 6(12):2979-88, 2013
Sohaib SA et al: Imaging of uterine malignancies. Semin Ultrasound CT MR. 31(5):377-87, 2010
Goto N et al: Magnetic resonance findings of primary uterine malignant lymphoma. Magn Reson Med Sci. 6(1):7-13, 2007
Niwa K et al: Primary lymphoma of the uterine corpus: an unusual location for a common disease--case report. Eur J Gynaecol Oncol. 28(6):522-3, 2007
Hamadani M et al: Marginal zone B-cell lymphoma of the uterus: a case report and review of the literature. J Okla State Med Assoc. 99(4):154-6, 2006
Keller C et al: Primary Burkitt lymphoma of the uterine corpus. Leuk Lymphoma. 47(1):141-5, 2006
Lagoo AS et al: Lymphoma of the female genital tract: current status. Int J Gynecol Pathol. 25(1):1-21, 2006
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