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Genital Metastases
Christine O. Menias, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Uterine, cervical, or vaginal metastases
              • Definitions

                • Secondary malignancy of uterus, cervix, or vagina

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Burger IA et al: The value of 18F-FDG PET/CT in recurrent gynecologic malignancies prior to pelvic exenteration. Gynecol Oncol. 129(3):586-92, 2013
                                        2. Carreras C et al: Rare metastases detected by (68)Ga-somatostatin receptor PET/CT in patients with neuroendocrine tumors. Recent Results Cancer Res. 194:379-84, 2013
                                        3. Sanuki N et al: Evaluation of microscopic tumor extension in early-stage cervical cancer: quantifying subclinical uncertainties by pathological and magnetic resonance imaging findings. J Radiat Res. 54(4):719-26, 2013
                                        4. Alt CD et al: Imaging of female pelvic malignancies regarding MRI, CT, and PET/CT: Part 2. Strahlenther Onkol. 187(11):705-14, 2011
                                        5. Brocker KA et al: Imaging of female pelvic malignancies regarding MRI, CT, and PET/CT : part 1. Strahlenther Onkol. 187(10):611-8, 2011
                                        6. Fischerova D: Ultrasound scanning of the pelvis and abdomen for staging of gynecological tumors: a review. Ultrasound Obstet Gynecol. 38(3):246-66, 2011
                                        7. Levy A et al: Interest of diffusion-weighted echo-planar MR imaging and apparent diffusion coefficient mapping in gynecological malignancies: a review. J Magn Reson Imaging. 33(5):1020-7, 2011
                                        8. Bogliolo S et al: Breast cancer with synchronous massive metastasis in the uterine cervix: a case report and review of the literature. Arch Gynecol Obstet. 281(4):769-73, 2010
                                        9. Cagayan MS: Vaginal metastases complicating gestational trophoblastic neoplasia. J Reprod Med. 55(5-6):229-35, 2010
                                        10. Ceccaroni M et al: Symptomatic vaginal bleeding in a postmenopausal woman revealing colon adenocarcinoma metastasizing exclusively to the vagina. J Minim Invasive Gynecol. 17(6):779-81, 2010
                                        11. Colling R et al: Endometrial metastasis of colorectal cancer with coincident endometrial adenocarcinoma. BMJ Case Rep. 2010, 2010
                                        12. D'souza MM et al: Cervical and uterine metastasis from carcinoma of breast diagnosed by PET/CT: an unusual presentation. Clin Nucl Med. 35(10):820-3, 2010
                                        13. Grant LA et al: Congenital and acquired conditions of the vulva and vagina on magnetic resonance imaging: a pictorial review. Semin Ultrasound CT MR. 31(5):347-62, 2010
                                        14. Sahdev A: Cervical tumors. Semin Ultrasound CT MR. 31(5):399-413, 2010
                                        15. Sohaib SA et al: Imaging of uterine malignancies. Semin Ultrasound CT MR. 31(5):377-87, 2010
                                        16. Sundaram PS et al: Staring secondaries, where is the primary? Indian J Med Paediatr Oncol. 31(4):148-50, 2010
                                        17. Griffin N et al: Magnetic resonance imaging of vaginal and vulval pathology. Eur Radiol. 18(6):1269-80, 2008
                                        18. Kang WD et al: Hepatocellular carcinoma presenting as uterine metastasis. Cancer Res Treat. 40(3):141-4, 2008
                                        19. Parikh JH et al: MR imaging features of vaginal malignancies. Radiographics. 28(1):49-63; quiz 322, 2008
                                        20. Hauth EA et al: [Magnetic resonance imaging in the diagnosis of benign and malignant pelvic tumors.] Rofo. 176(6):817-28, 2004
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Uterine, cervical, or vaginal metastases
                                                    • Definitions

                                                      • Secondary malignancy of uterus, cervix, or vagina

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Burger IA et al: The value of 18F-FDG PET/CT in recurrent gynecologic malignancies prior to pelvic exenteration. Gynecol Oncol. 129(3):586-92, 2013
                                                                              2. Carreras C et al: Rare metastases detected by (68)Ga-somatostatin receptor PET/CT in patients with neuroendocrine tumors. Recent Results Cancer Res. 194:379-84, 2013
                                                                              3. Sanuki N et al: Evaluation of microscopic tumor extension in early-stage cervical cancer: quantifying subclinical uncertainties by pathological and magnetic resonance imaging findings. J Radiat Res. 54(4):719-26, 2013
                                                                              4. Alt CD et al: Imaging of female pelvic malignancies regarding MRI, CT, and PET/CT: Part 2. Strahlenther Onkol. 187(11):705-14, 2011
                                                                              5. Brocker KA et al: Imaging of female pelvic malignancies regarding MRI, CT, and PET/CT : part 1. Strahlenther Onkol. 187(10):611-8, 2011
                                                                              6. Fischerova D: Ultrasound scanning of the pelvis and abdomen for staging of gynecological tumors: a review. Ultrasound Obstet Gynecol. 38(3):246-66, 2011
                                                                              7. Levy A et al: Interest of diffusion-weighted echo-planar MR imaging and apparent diffusion coefficient mapping in gynecological malignancies: a review. J Magn Reson Imaging. 33(5):1020-7, 2011
                                                                              8. Bogliolo S et al: Breast cancer with synchronous massive metastasis in the uterine cervix: a case report and review of the literature. Arch Gynecol Obstet. 281(4):769-73, 2010
                                                                              9. Cagayan MS: Vaginal metastases complicating gestational trophoblastic neoplasia. J Reprod Med. 55(5-6):229-35, 2010
                                                                              10. Ceccaroni M et al: Symptomatic vaginal bleeding in a postmenopausal woman revealing colon adenocarcinoma metastasizing exclusively to the vagina. J Minim Invasive Gynecol. 17(6):779-81, 2010
                                                                              11. Colling R et al: Endometrial metastasis of colorectal cancer with coincident endometrial adenocarcinoma. BMJ Case Rep. 2010, 2010
                                                                              12. D'souza MM et al: Cervical and uterine metastasis from carcinoma of breast diagnosed by PET/CT: an unusual presentation. Clin Nucl Med. 35(10):820-3, 2010
                                                                              13. Grant LA et al: Congenital and acquired conditions of the vulva and vagina on magnetic resonance imaging: a pictorial review. Semin Ultrasound CT MR. 31(5):347-62, 2010
                                                                              14. Sahdev A: Cervical tumors. Semin Ultrasound CT MR. 31(5):399-413, 2010
                                                                              15. Sohaib SA et al: Imaging of uterine malignancies. Semin Ultrasound CT MR. 31(5):377-87, 2010
                                                                              16. Sundaram PS et al: Staring secondaries, where is the primary? Indian J Med Paediatr Oncol. 31(4):148-50, 2010
                                                                              17. Griffin N et al: Magnetic resonance imaging of vaginal and vulval pathology. Eur Radiol. 18(6):1269-80, 2008
                                                                              18. Kang WD et al: Hepatocellular carcinoma presenting as uterine metastasis. Cancer Res Treat. 40(3):141-4, 2008
                                                                              19. Parikh JH et al: MR imaging features of vaginal malignancies. Radiographics. 28(1):49-63; quiz 322, 2008
                                                                              20. Hauth EA et al: [Magnetic resonance imaging in the diagnosis of benign and malignant pelvic tumors.] Rofo. 176(6):817-28, 2004