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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Germ cell tumor (GCT)
Synonyms
- Teratoma, seminoma, nonseminomatous germ cell tumor (NSGCT)
Definitions
- Tumor derived from primordial germ cells
- Teratoma: 3 major types
- Mature teratoma: Characterized by mixture of adult-type tissues derived from 3 germinal layers
- Immature teratoma: Contains embryonic or fetal tissue, often neuroepithelial structures
- Malignant teratoma: Contains foci of malignant transformation
- Malignant GCT: Seminoma & NSGCT
- Seminoma: Germinoma & dysgerminoma
- NSGCT: Embryonal cell, yolk sac tumor (YST), choriocarcinoma, & mixed GCT
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Olson TA et al: Pediatric and adolescent extracranial germ cell tumors: the road to collaboration. J Clin Oncol. 33(27):3018-28, 2015
- Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
- Petroze R et al: Pediatric chest II: Benign tumors and cysts. Surg Clin North Am. 92(3):645-58, ix, 2012
- Horton Z et al: Pediatric germ cell tumors. Surg Oncol. 16(3):205-13, 2007
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Germ cell tumor (GCT)
Synonyms
- Teratoma, seminoma, nonseminomatous germ cell tumor (NSGCT)
Definitions
- Tumor derived from primordial germ cells
- Teratoma: 3 major types
- Mature teratoma: Characterized by mixture of adult-type tissues derived from 3 germinal layers
- Immature teratoma: Contains embryonic or fetal tissue, often neuroepithelial structures
- Malignant teratoma: Contains foci of malignant transformation
- Malignant GCT: Seminoma & NSGCT
- Seminoma: Germinoma & dysgerminoma
- NSGCT: Embryonal cell, yolk sac tumor (YST), choriocarcinoma, & mixed GCT
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Olson TA et al: Pediatric and adolescent extracranial germ cell tumors: the road to collaboration. J Clin Oncol. 33(27):3018-28, 2015
- Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
- Petroze R et al: Pediatric chest II: Benign tumors and cysts. Surg Clin North Am. 92(3):645-58, ix, 2012
- Horton Z et al: Pediatric germ cell tumors. Surg Oncol. 16(3):205-13, 2007
