Tumor of primordial germ cells, essentially identical to gonadal or extragonadal seminoma & dysgerminoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Reporting Tips
Selected References
Hirata K et al: Time to diagnosis and clinical characteristics in pediatric brain tumor patients. Childs Nerv Syst. 36(9):2047-54, 2020
Juliano J et al: Imaging features predictive of recurrence in pediatric intracranial germ-cell tumors. Pediatr Neurosurg. 1-8, 2019
Wu CC et al: MRI features of pediatric intracranial germ cell tumor subtypes. J Neurooncol. 134(1):221-30, 2017
Choudhri AF et al: Diffusion characteristics of pediatric pineal tumors. Neuroradiol J. 28(2):209-16, 2015
Osorio DS et al: Management of CNS germinoma. CNS Oncol. 4(4):273-9, 2015
Awa R et al: Neuroimaging diagnosis of pineal region tumors-quest for pathognomonic finding of germinoma. Neuroradiology. 56(7):525-34, 2014
Kakigi T et al: Quantitative imaging values of CT, MR, and FDG-PET to differentiate pineal parenchymal tumors and germinomas: are they useful? Neuroradiology. 56(4):297-303, 2014
Plaza MJ et al: Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol. 200(5):1115-24, 2013
Shim KW et al: Treatment strategy for intracranial primary pure germinoma. Childs Nerv Syst. 29(2):239-48, 2013
Chen YW et al: Change in treatment strategy for intracranial germinoma: long-term follow-up experience at a single institute. Cancer. 118(10):2752-62, 2012
Dumrongpisutikul N et al: Distinguishing between germinomas and pineal cell tumors on MR imaging. AJNR Am J Neuroradiol. 33(3):550-5, 2012
Wang Y et al: Intracranial germinoma: clinical and MRI findings in 56 patients. Childs Nerv Syst. 26(12):1773-7, 2010
Kanamori M et al: Optimal treatment strategy for intracranial germ cell tumors: a single institution analysis. J Neurosurg Pediatr. 4(6):506-14, 2009
Tian C et al: Is biopsy needed to guide management for all patients with presumed intracranial ectopic germinomas. J Neurooncol. 92(1):37-44, 2009
Ogino H et al: CNS germinoma with elevated serum human chorionic gonadotropin level: clinical characteristics and treatment outcome. Int J Radiat Oncol Biol Phys. 62(3):803-8, 2005
Wellons JC 3rd et al: Neuroendoscopic findings in patients with intracranial germinomas correlating with diabetes insipidus. J Neurosurg Spine. 100(5):430-6, 2004
Gömöri E et al: Cytogenetic profile of primary pituitary germinoma. J Neurooncol. 50(3):251-5, 2000
Tumor of primordial germ cells, essentially identical to gonadal or extragonadal seminoma & dysgerminoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Reporting Tips
Selected References
Hirata K et al: Time to diagnosis and clinical characteristics in pediatric brain tumor patients. Childs Nerv Syst. 36(9):2047-54, 2020
Juliano J et al: Imaging features predictive of recurrence in pediatric intracranial germ-cell tumors. Pediatr Neurosurg. 1-8, 2019
Wu CC et al: MRI features of pediatric intracranial germ cell tumor subtypes. J Neurooncol. 134(1):221-30, 2017
Choudhri AF et al: Diffusion characteristics of pediatric pineal tumors. Neuroradiol J. 28(2):209-16, 2015
Osorio DS et al: Management of CNS germinoma. CNS Oncol. 4(4):273-9, 2015
Awa R et al: Neuroimaging diagnosis of pineal region tumors-quest for pathognomonic finding of germinoma. Neuroradiology. 56(7):525-34, 2014
Kakigi T et al: Quantitative imaging values of CT, MR, and FDG-PET to differentiate pineal parenchymal tumors and germinomas: are they useful? Neuroradiology. 56(4):297-303, 2014
Plaza MJ et al: Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol. 200(5):1115-24, 2013
Shim KW et al: Treatment strategy for intracranial primary pure germinoma. Childs Nerv Syst. 29(2):239-48, 2013
Chen YW et al: Change in treatment strategy for intracranial germinoma: long-term follow-up experience at a single institute. Cancer. 118(10):2752-62, 2012
Dumrongpisutikul N et al: Distinguishing between germinomas and pineal cell tumors on MR imaging. AJNR Am J Neuroradiol. 33(3):550-5, 2012
Wang Y et al: Intracranial germinoma: clinical and MRI findings in 56 patients. Childs Nerv Syst. 26(12):1773-7, 2010
Kanamori M et al: Optimal treatment strategy for intracranial germ cell tumors: a single institution analysis. J Neurosurg Pediatr. 4(6):506-14, 2009
Tian C et al: Is biopsy needed to guide management for all patients with presumed intracranial ectopic germinomas. J Neurooncol. 92(1):37-44, 2009
Ogino H et al: CNS germinoma with elevated serum human chorionic gonadotropin level: clinical characteristics and treatment outcome. Int J Radiat Oncol Biol Phys. 62(3):803-8, 2005
Wellons JC 3rd et al: Neuroendoscopic findings in patients with intracranial germinomas correlating with diabetes insipidus. J Neurosurg Spine. 100(5):430-6, 2004
Gömöri E et al: Cytogenetic profile of primary pituitary germinoma. J Neurooncol. 50(3):251-5, 2000