link
Bookmarks
Glomus Jugulare Paraganglioma
Karen L. Salzman, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
11
14
15

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Glomus jugulare paraganglioma (GJP)
          • Synonyms

            • Glomus jugulotympanicum paraganglioma, jugular foramen (JF) paraganglioma, chemodectoma
          • Definitions

            • Benign tumor arising from neural crest progenitor cells (glomus bodies) located in & around JF

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Angiographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Li D et al: Less-aggressive surgical management and long-term outcomes of jugular foramen paragangliomas: a neurosurgical perspective. J Neurosurg. 1-12, 2016
                                            2. Schmalbach CE et al: Managing Vascular Tumors-Open Approaches. Otolaryngol Clin North Am. 49(3):777-90, 2016
                                            3. Baysal BE et al: 15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma-paraganglioma syndromes characterized by germline SDHB and SDHD mutations. Endocr Relat Cancer. 22(4):T71-82, 2015
                                            4. Griauzde J et al: Imaging of vascular lesions of the head and neck. Radiol Clin North Am. 53(1):197-213, 2015
                                            5. Scheick SM et al: Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas. Am J Clin Oncol. ePub, 2015
                                            6. Wanna GB et al: Contemporary management of jugular paragangliomas. Otolaryngol Clin North Am. 48(2):331-41, 2015
                                            7. Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
                                            8. Collins N et al: Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation. J Vasc Surg. 55(1):216-9, 2012
                                            9. Sismanis A: Pulsatile tinnitus: contemporary assessment and management. Curr Opin Otolaryngol Head Neck Surg. 19(5):348-57, 2011
                                            10. Aliabadi H et al: Bevacizumab fails to treat temporal paraganglioma: discussion and case illustration. J Neurooncol. 98(3):427-30, 2010
                                            11. Borba LA et al: Surgical management of glomus jugulare tumors: a proposal for approach selection based on tumor relationships with the facial nerve. J Neurosurg. 112(1):88-98, 2010
                                            12. Chen PG et al: Treatment of glomus jugulare tumors with gamma knife radiosurgery. Laryngoscope. Epub ahead of print, 2010
                                            13. Christie A et al: A comparative review of multidetector CT angiography and MRI in the diagnosis of jugular foramen lesions. Clin Radiol. 65(3):213-7, 2010
                                            14. Fayad JN et al: Jugular foramen tumors: clinical characteristics and treatment outcomes. Otol Neurotol. 31(2):299-305, 2010
                                            15. Karaman E et al: Management of jugular paragangliomas in otolaryngology practice. J Craniofac Surg. 21(1):117-20, 2010
                                            16. Navarro Martín A et al: Successful treatment of glomus jugulare tumours with gamma knife radiosurgery: clinical and physical aspects of management and review of the literature. Clin Transl Oncol. 12(1):55-62, 2010
                                            17. Alaani A et al: The crucial role of imaging in determining the approach to glomus tympanicum tumours. Eur Arch Otorhinolaryngol. 266(6):827-31, 2009
                                            18. Fayad JN et al: Treatment of recurrent and residual glomus jugulare tumors. Skull Base. 19(1):92-8, 2009
                                            19. Guss ZD et al: Radiosurgery for glomus jugulare: history and recent progress. Neurosurg Focus. 27(6):E5, 2009
                                            20. Miller JP et al: Radiosurgery for glomus jugulare tumors. Otolaryngol Clin North Am. 42(4):689-706, 2009
                                            21. Boedeker CC et al: Malignant head and neck paragangliomas in SDHB mutation carriers. Otolaryngol Head Neck Surg. 137(1):126-9, 2007
                                            22. Piazza P et al: Absence of the contralateral internal carotid artery: a challenge for management of ipsilateral glomus jugulare and glomus vagale tumors. Laryngoscope. 117(8):1333-7, 2007
                                            23. Feigl GC et al: Intracranial glomus jugulare tumors: volume reduction with Gamma Knife surgery. J Neurosurg. 105 Suppl:161-7, 2006
                                            24. Hirunpat S et al: Nasopharyngeal extension of glomus tympanicum: an unusual clinical and imaging manifestation. AJNR Am J Neuroradiol. 27(9):1820-2, 2006
                                            25. Robinson DH: Vascular lesions of the skull base: endovascular prospective for the otolaryngologist. Otolaryngol Clin North Am. 38(4):737-71, 2005
                                            26. Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
                                            27. Weissman JL et al: Imaging of tinnitus: a review. Radiology. 216(2):342-9, 2000
                                            28. Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
                                            29. Lustig LR et al: The variable relationship between the lower cranial nerves and jugular foramen tumors: implications for neural preservation. Am J Otol. 17(4):658-68, 1996
                                            30. Vogl TJ et al: Glomus tumors of the skull base: combined use of MR angiography and spin-echo imaging. Radiology. 192(1):103-10, 1994
                                            31. Weber AL et al: Radiologic evaluation of the jugular foramen. Anatomy, vascular variants, anomalies, and tumors. Neuroimaging Clin N Am. 4(3):579-98, 1994
                                            32. Gulya AJ: The glomus tumor and its biology. Laryngoscope. 103(11 Pt 2 Suppl 60):7-15, 1993
                                            33. Olsen WL et al: MR imaging of paragangliomas. AJR Am J Roentgenol. 148(1):201-4, 1987
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Glomus jugulare paraganglioma (GJP)
                                                    • Synonyms

                                                      • Glomus jugulotympanicum paraganglioma, jugular foramen (JF) paraganglioma, chemodectoma
                                                    • Definitions

                                                      • Benign tumor arising from neural crest progenitor cells (glomus bodies) located in & around JF

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Angiographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Li D et al: Less-aggressive surgical management and long-term outcomes of jugular foramen paragangliomas: a neurosurgical perspective. J Neurosurg. 1-12, 2016
                                                                                      2. Schmalbach CE et al: Managing Vascular Tumors-Open Approaches. Otolaryngol Clin North Am. 49(3):777-90, 2016
                                                                                      3. Baysal BE et al: 15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma-paraganglioma syndromes characterized by germline SDHB and SDHD mutations. Endocr Relat Cancer. 22(4):T71-82, 2015
                                                                                      4. Griauzde J et al: Imaging of vascular lesions of the head and neck. Radiol Clin North Am. 53(1):197-213, 2015
                                                                                      5. Scheick SM et al: Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas. Am J Clin Oncol. ePub, 2015
                                                                                      6. Wanna GB et al: Contemporary management of jugular paragangliomas. Otolaryngol Clin North Am. 48(2):331-41, 2015
                                                                                      7. Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
                                                                                      8. Collins N et al: Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation. J Vasc Surg. 55(1):216-9, 2012
                                                                                      9. Sismanis A: Pulsatile tinnitus: contemporary assessment and management. Curr Opin Otolaryngol Head Neck Surg. 19(5):348-57, 2011
                                                                                      10. Aliabadi H et al: Bevacizumab fails to treat temporal paraganglioma: discussion and case illustration. J Neurooncol. 98(3):427-30, 2010
                                                                                      11. Borba LA et al: Surgical management of glomus jugulare tumors: a proposal for approach selection based on tumor relationships with the facial nerve. J Neurosurg. 112(1):88-98, 2010
                                                                                      12. Chen PG et al: Treatment of glomus jugulare tumors with gamma knife radiosurgery. Laryngoscope. Epub ahead of print, 2010
                                                                                      13. Christie A et al: A comparative review of multidetector CT angiography and MRI in the diagnosis of jugular foramen lesions. Clin Radiol. 65(3):213-7, 2010
                                                                                      14. Fayad JN et al: Jugular foramen tumors: clinical characteristics and treatment outcomes. Otol Neurotol. 31(2):299-305, 2010
                                                                                      15. Karaman E et al: Management of jugular paragangliomas in otolaryngology practice. J Craniofac Surg. 21(1):117-20, 2010
                                                                                      16. Navarro Martín A et al: Successful treatment of glomus jugulare tumours with gamma knife radiosurgery: clinical and physical aspects of management and review of the literature. Clin Transl Oncol. 12(1):55-62, 2010
                                                                                      17. Alaani A et al: The crucial role of imaging in determining the approach to glomus tympanicum tumours. Eur Arch Otorhinolaryngol. 266(6):827-31, 2009
                                                                                      18. Fayad JN et al: Treatment of recurrent and residual glomus jugulare tumors. Skull Base. 19(1):92-8, 2009
                                                                                      19. Guss ZD et al: Radiosurgery for glomus jugulare: history and recent progress. Neurosurg Focus. 27(6):E5, 2009
                                                                                      20. Miller JP et al: Radiosurgery for glomus jugulare tumors. Otolaryngol Clin North Am. 42(4):689-706, 2009
                                                                                      21. Boedeker CC et al: Malignant head and neck paragangliomas in SDHB mutation carriers. Otolaryngol Head Neck Surg. 137(1):126-9, 2007
                                                                                      22. Piazza P et al: Absence of the contralateral internal carotid artery: a challenge for management of ipsilateral glomus jugulare and glomus vagale tumors. Laryngoscope. 117(8):1333-7, 2007
                                                                                      23. Feigl GC et al: Intracranial glomus jugulare tumors: volume reduction with Gamma Knife surgery. J Neurosurg. 105 Suppl:161-7, 2006
                                                                                      24. Hirunpat S et al: Nasopharyngeal extension of glomus tympanicum: an unusual clinical and imaging manifestation. AJNR Am J Neuroradiol. 27(9):1820-2, 2006
                                                                                      25. Robinson DH: Vascular lesions of the skull base: endovascular prospective for the otolaryngologist. Otolaryngol Clin North Am. 38(4):737-71, 2005
                                                                                      26. Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
                                                                                      27. Weissman JL et al: Imaging of tinnitus: a review. Radiology. 216(2):342-9, 2000
                                                                                      28. Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
                                                                                      29. Lustig LR et al: The variable relationship between the lower cranial nerves and jugular foramen tumors: implications for neural preservation. Am J Otol. 17(4):658-68, 1996
                                                                                      30. Vogl TJ et al: Glomus tumors of the skull base: combined use of MR angiography and spin-echo imaging. Radiology. 192(1):103-10, 1994
                                                                                      31. Weber AL et al: Radiologic evaluation of the jugular foramen. Anatomy, vascular variants, anomalies, and tumors. Neuroimaging Clin N Am. 4(3):579-98, 1994
                                                                                      32. Gulya AJ: The glomus tumor and its biology. Laryngoscope. 103(11 Pt 2 Suppl 60):7-15, 1993
                                                                                      33. Olsen WL et al: MR imaging of paragangliomas. AJR Am J Roentgenol. 148(1):201-4, 1987