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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Glomus vagale paraganglioma (GVP)
Synonyms
- Vagal paraganglioma (PGL)
- Vagale chemodectoma
- Nonchromaffin PGL
Definitions
- Benign vascular tumor arising in glomus bodies associated with nodose ganglion of vagus nerve
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Anderson RC et al: Management impact of 68Ga-DOTATATE PET/CT in neuroendocrine tumors. Nucl Med Mol Imaging. 55(1):31-7, 2021
- Contrera KJ et al: Recurrence and progression of head and neck paragangliomas after treatment. Otolaryngol Head Neck Surg. 162(4):504-11, 2020
- Fatima N et al: Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis. Neurosurg Rev. 44(2):741-52, 2020
- Bhatt S et al: Glomus vagale tumour, can it be diagnosed only on sonography? J Ultrasound. 20(1):73-9, 2017
- Gaddikeri S et al: Dynamic contrast-enhanced MRI in the evaluation of carotid space paraganglioma versus schwannoma. J Neuroimaging. 26(6):618-25, 2016
- Moore MG et al: Head and neck paragangliomas: an update on evaluation and management. Otolaryngol Head Neck Surg. 154(4):597-605, 2016
- Woolen S et al: Paragangliomas of the head and neck. Neuroimaging Clin N Am. 26(2):259-78, 2016
- Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
- Goyal A et al: Fine needle aspiration of vagal paraganglioma: an interesting clinical presentation. Diagn Cytopathol. 40(7):651-2, 2012
- Neskey DM et al: Outcomes after surgical resection of head and neck paragangliomas: a review of 61 patients. Skull Base. 21(3):171-6, 2011
- Papaspyrou K et al: Management of head and neck paragangliomas: review of 120 patients. Head Neck. 31(3):381-7, 2009
- Karatas E et al: Synchronous bilateral carotid body tumor and vagal paraganglioma: a case report and review of literature. Auris Nasus Larynx. 35(1):171-5, 2008
- Koopmans KP et al: 111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigraphic detection of head and neck paragangliomas. J Nucl Med. 49(8):1232-7, 2008
- Lozano FS et al: Surgery of vagal paragangliomas: six patients and review of literature. Surg Oncol. 17(4):281-7, 2008
- SEER Program Coding and Staging Manual (SPCSM) with 2008 Revisions. Bethesda, MD: National Cancer Institute, 2008
- Paal E: Head and neck pathology–radiology classics: vagal paraganglioma. Head Neck Path. 1(1):35-37, 2007
- Yanbuloğlu B et al: Two synchronous glomus tumors simulating a single mass: glomus vagale and glomus caroticum. Diagn Interv Radiol. 12(4):177-9, 2006
- Zanoletti E et al: Vagal paraganglioma. Skull Base. 16(3):161-7, 2006
- Hinerman RW et al: Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale. Head Neck. 23(5):363-71, 2001
- Koischwitz D et al: Ultrasound of the neck. Radiol Clin North Am. 38(5):1029-45, 2000
- Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
- Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
- Evenson LJ et al: Radiotherapy in the management of chemodectomas of the carotid body and glomus vagale. Head Neck. 20(7):609-13, 1998
- Levin RJ et al: Dopamine-secreting glomus vagale: a case report and histopathologic correlation. Head Neck. 20(8):753-7, 1998
- Netterville JL et al: Vagal paraganglioma: a review of 46 patients treated during a 20-year period. Arch Otolaryngol Head Neck Surg. 124(10):1133-40, 1998
- Muhm M et al: Diagnostic and therapeutic approaches to carotid body tumors. Review of 24 patients. Arch Surg. 132(3):279-84, 1997
- Walsh RM et al: Malignant vagal paraganglioma. J Laryngol Otol. 111(1):83-8, 1997
- Borba LA et al: Intravagal paragangliomas: report of four cases. Neurosurgery. 38(3):569-75; discussion 575, 1996
- Cole JM et al: Long-term results of treatment for glomus jugulare and glomus vagale tumors with radiotherapy. Laryngoscope. 104(12):1461-5, 1994
- McCaffrey TV et al: Familial paragangliomas of the head and neck. Arch Otolaryngol Head Neck Surg. 120(11):1211-6, 1994
- Urquhart AC et al: Glomus vagale: paraganglioma of the vagus nerve. Laryngoscope. 104(4):440-5, 1994
- Eriksen C et al: Vagal paragangliomas: a report of nine cases. Am J Otolaryngol. 12(5):278-87, 1991
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Glomus vagale paraganglioma (GVP)
Synonyms
- Vagal paraganglioma (PGL)
- Vagale chemodectoma
- Nonchromaffin PGL
Definitions
- Benign vascular tumor arising in glomus bodies associated with nodose ganglion of vagus nerve
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Anderson RC et al: Management impact of 68Ga-DOTATATE PET/CT in neuroendocrine tumors. Nucl Med Mol Imaging. 55(1):31-7, 2021
- Contrera KJ et al: Recurrence and progression of head and neck paragangliomas after treatment. Otolaryngol Head Neck Surg. 162(4):504-11, 2020
- Fatima N et al: Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis. Neurosurg Rev. 44(2):741-52, 2020
- Bhatt S et al: Glomus vagale tumour, can it be diagnosed only on sonography? J Ultrasound. 20(1):73-9, 2017
- Gaddikeri S et al: Dynamic contrast-enhanced MRI in the evaluation of carotid space paraganglioma versus schwannoma. J Neuroimaging. 26(6):618-25, 2016
- Moore MG et al: Head and neck paragangliomas: an update on evaluation and management. Otolaryngol Head Neck Surg. 154(4):597-605, 2016
- Woolen S et al: Paragangliomas of the head and neck. Neuroimaging Clin N Am. 26(2):259-78, 2016
- Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
- Goyal A et al: Fine needle aspiration of vagal paraganglioma: an interesting clinical presentation. Diagn Cytopathol. 40(7):651-2, 2012
- Neskey DM et al: Outcomes after surgical resection of head and neck paragangliomas: a review of 61 patients. Skull Base. 21(3):171-6, 2011
- Papaspyrou K et al: Management of head and neck paragangliomas: review of 120 patients. Head Neck. 31(3):381-7, 2009
- Karatas E et al: Synchronous bilateral carotid body tumor and vagal paraganglioma: a case report and review of literature. Auris Nasus Larynx. 35(1):171-5, 2008
- Koopmans KP et al: 111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigraphic detection of head and neck paragangliomas. J Nucl Med. 49(8):1232-7, 2008
- Lozano FS et al: Surgery of vagal paragangliomas: six patients and review of literature. Surg Oncol. 17(4):281-7, 2008
- SEER Program Coding and Staging Manual (SPCSM) with 2008 Revisions. Bethesda, MD: National Cancer Institute, 2008
- Paal E: Head and neck pathology–radiology classics: vagal paraganglioma. Head Neck Path. 1(1):35-37, 2007
- Yanbuloğlu B et al: Two synchronous glomus tumors simulating a single mass: glomus vagale and glomus caroticum. Diagn Interv Radiol. 12(4):177-9, 2006
- Zanoletti E et al: Vagal paraganglioma. Skull Base. 16(3):161-7, 2006
- Hinerman RW et al: Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale. Head Neck. 23(5):363-71, 2001
- Koischwitz D et al: Ultrasound of the neck. Radiol Clin North Am. 38(5):1029-45, 2000
- Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
- Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
- Evenson LJ et al: Radiotherapy in the management of chemodectomas of the carotid body and glomus vagale. Head Neck. 20(7):609-13, 1998
- Levin RJ et al: Dopamine-secreting glomus vagale: a case report and histopathologic correlation. Head Neck. 20(8):753-7, 1998
- Netterville JL et al: Vagal paraganglioma: a review of 46 patients treated during a 20-year period. Arch Otolaryngol Head Neck Surg. 124(10):1133-40, 1998
- Muhm M et al: Diagnostic and therapeutic approaches to carotid body tumors. Review of 24 patients. Arch Surg. 132(3):279-84, 1997
- Walsh RM et al: Malignant vagal paraganglioma. J Laryngol Otol. 111(1):83-8, 1997
- Borba LA et al: Intravagal paragangliomas: report of four cases. Neurosurgery. 38(3):569-75; discussion 575, 1996
- Cole JM et al: Long-term results of treatment for glomus jugulare and glomus vagale tumors with radiotherapy. Laryngoscope. 104(12):1461-5, 1994
- McCaffrey TV et al: Familial paragangliomas of the head and neck. Arch Otolaryngol Head Neck Surg. 120(11):1211-6, 1994
- Urquhart AC et al: Glomus vagale: paraganglioma of the vagus nerve. Laryngoscope. 104(4):440-5, 1994
- Eriksen C et al: Vagal paragangliomas: a report of nine cases. Am J Otolaryngol. 12(5):278-87, 1991
