Benign vascular tumor arising in glomus bodies associated with nodose ganglion of vagus nerve
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Anderson RC et al: Management impact of 68Ga-DOTATATE PET/CT in neuroendocrine tumors. Nucl Med Mol Imaging. 55(1):31-7, 2021
Contrera KJ et al: Recurrence and progression of head and neck paragangliomas after treatment. Otolaryngol Head Neck Surg. 162(4):504-11, 2020
Fatima N et al: Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis. Neurosurg Rev. 44(2):741-52, 2020
Bhatt S et al: Glomus vagale tumour, can it be diagnosed only on sonography? J Ultrasound. 20(1):73-9, 2017
Gaddikeri S et al: Dynamic contrast-enhanced MRI in the evaluation of carotid space paraganglioma versus schwannoma. J Neuroimaging. 26(6):618-25, 2016
Moore MG et al: Head and neck paragangliomas: an update on evaluation and management. Otolaryngol Head Neck Surg. 154(4):597-605, 2016
Woolen S et al: Paragangliomas of the head and neck. Neuroimaging Clin N Am. 26(2):259-78, 2016
Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
Goyal A et al: Fine needle aspiration of vagal paraganglioma: an interesting clinical presentation. Diagn Cytopathol. 40(7):651-2, 2012
Neskey DM et al: Outcomes after surgical resection of head and neck paragangliomas: a review of 61 patients. Skull Base. 21(3):171-6, 2011
Papaspyrou K et al: Management of head and neck paragangliomas: review of 120 patients. Head Neck. 31(3):381-7, 2009
Karatas E et al: Synchronous bilateral carotid body tumor and vagal paraganglioma: a case report and review of literature. Auris Nasus Larynx. 35(1):171-5, 2008
Koopmans KP et al: 111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigraphic detection of head and neck paragangliomas. J Nucl Med. 49(8):1232-7, 2008
Lozano FS et al: Surgery of vagal paragangliomas: six patients and review of literature. Surg Oncol. 17(4):281-7, 2008
SEER Program Coding and Staging Manual (SPCSM) with 2008 Revisions. Bethesda, MD: National Cancer Institute, 2008
Paal E: Head and neck pathology–radiology classics: vagal paraganglioma. Head Neck Path. 1(1):35-37, 2007
Yanbuloğlu B et al: Two synchronous glomus tumors simulating a single mass: glomus vagale and glomus caroticum. Diagn Interv Radiol. 12(4):177-9, 2006
Zanoletti E et al: Vagal paraganglioma. Skull Base. 16(3):161-7, 2006
Hinerman RW et al: Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale. Head Neck. 23(5):363-71, 2001
Koischwitz D et al: Ultrasound of the neck. Radiol Clin North Am. 38(5):1029-45, 2000
Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
Evenson LJ et al: Radiotherapy in the management of chemodectomas of the carotid body and glomus vagale. Head Neck. 20(7):609-13, 1998
Levin RJ et al: Dopamine-secreting glomus vagale: a case report and histopathologic correlation. Head Neck. 20(8):753-7, 1998
Netterville JL et al: Vagal paraganglioma: a review of 46 patients treated during a 20-year period. Arch Otolaryngol Head Neck Surg. 124(10):1133-40, 1998
Muhm M et al: Diagnostic and therapeutic approaches to carotid body tumors. Review of 24 patients. Arch Surg. 132(3):279-84, 1997
Borba LA et al: Intravagal paragangliomas: report of four cases. Neurosurgery. 38(3):569-75; discussion 575, 1996
Cole JM et al: Long-term results of treatment for glomus jugulare and glomus vagale tumors with radiotherapy. Laryngoscope. 104(12):1461-5, 1994
McCaffrey TV et al: Familial paragangliomas of the head and neck. Arch Otolaryngol Head Neck Surg. 120(11):1211-6, 1994
Urquhart AC et al: Glomus vagale: paraganglioma of the vagus nerve. Laryngoscope. 104(4):440-5, 1994
Eriksen C et al: Vagal paragangliomas: a report of nine cases. Am J Otolaryngol. 12(5):278-87, 1991
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Glomus vagale paraganglioma (GVP)
Synonyms
Vagal paraganglioma (PGL)
Vagale chemodectoma
Nonchromaffin PGL
Definitions
Benign vascular tumor arising in glomus bodies associated with nodose ganglion of vagus nerve
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Anderson RC et al: Management impact of 68Ga-DOTATATE PET/CT in neuroendocrine tumors. Nucl Med Mol Imaging. 55(1):31-7, 2021
Contrera KJ et al: Recurrence and progression of head and neck paragangliomas after treatment. Otolaryngol Head Neck Surg. 162(4):504-11, 2020
Fatima N et al: Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis. Neurosurg Rev. 44(2):741-52, 2020
Bhatt S et al: Glomus vagale tumour, can it be diagnosed only on sonography? J Ultrasound. 20(1):73-9, 2017
Gaddikeri S et al: Dynamic contrast-enhanced MRI in the evaluation of carotid space paraganglioma versus schwannoma. J Neuroimaging. 26(6):618-25, 2016
Moore MG et al: Head and neck paragangliomas: an update on evaluation and management. Otolaryngol Head Neck Surg. 154(4):597-605, 2016
Woolen S et al: Paragangliomas of the head and neck. Neuroimaging Clin N Am. 26(2):259-78, 2016
Gilbo P et al: Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer. 120(23):3738-43, 2014
Goyal A et al: Fine needle aspiration of vagal paraganglioma: an interesting clinical presentation. Diagn Cytopathol. 40(7):651-2, 2012
Neskey DM et al: Outcomes after surgical resection of head and neck paragangliomas: a review of 61 patients. Skull Base. 21(3):171-6, 2011
Papaspyrou K et al: Management of head and neck paragangliomas: review of 120 patients. Head Neck. 31(3):381-7, 2009
Karatas E et al: Synchronous bilateral carotid body tumor and vagal paraganglioma: a case report and review of literature. Auris Nasus Larynx. 35(1):171-5, 2008
Koopmans KP et al: 111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigraphic detection of head and neck paragangliomas. J Nucl Med. 49(8):1232-7, 2008
Lozano FS et al: Surgery of vagal paragangliomas: six patients and review of literature. Surg Oncol. 17(4):281-7, 2008
SEER Program Coding and Staging Manual (SPCSM) with 2008 Revisions. Bethesda, MD: National Cancer Institute, 2008
Paal E: Head and neck pathology–radiology classics: vagal paraganglioma. Head Neck Path. 1(1):35-37, 2007
Yanbuloğlu B et al: Two synchronous glomus tumors simulating a single mass: glomus vagale and glomus caroticum. Diagn Interv Radiol. 12(4):177-9, 2006
Zanoletti E et al: Vagal paraganglioma. Skull Base. 16(3):161-7, 2006
Hinerman RW et al: Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale. Head Neck. 23(5):363-71, 2001
Koischwitz D et al: Ultrasound of the neck. Radiol Clin North Am. 38(5):1029-45, 2000
Mafee MF et al: Glomus faciale, glomus jugulare, glomus tympanicum, glomus vagale, carotid body tumors, and simulating lesions. Role of MR imaging. Radiol Clin North Am. 38(5):1059-76, 2000
Rao AB et al: From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 19(6):1605-32, 1999
Evenson LJ et al: Radiotherapy in the management of chemodectomas of the carotid body and glomus vagale. Head Neck. 20(7):609-13, 1998
Levin RJ et al: Dopamine-secreting glomus vagale: a case report and histopathologic correlation. Head Neck. 20(8):753-7, 1998
Netterville JL et al: Vagal paraganglioma: a review of 46 patients treated during a 20-year period. Arch Otolaryngol Head Neck Surg. 124(10):1133-40, 1998
Muhm M et al: Diagnostic and therapeutic approaches to carotid body tumors. Review of 24 patients. Arch Surg. 132(3):279-84, 1997