link
Bookmarks
 (0)
Head and Neck
Diagnosis
Primary Sites, Perineural Tumor and Nodes
Laryngeal Carcinoma
Glottic Laryngeal Squamous Cell Carcinoma
Glottic Laryngeal Squamous Cell Carcinoma
Patricia A. Hudgins, MD, FACR
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
1
6
2
1

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Glottic squamous cell carcinoma (G-SCCa)

            • Definitions

              • SCCa arising on mucosal surface of glottic larynx
                • Vocal cord, anterior and posterior commissures

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        • Ultrasonographic Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                • Reporting Tips

                                                  Selected References

                                                  1. Brady JS et al: Survival Impact of Initial Therapy in Patients with T1-T2 Glottic Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. ePub, 2016
                                                  2. Monnier Y et al: Transthyrohyoid access to the larynx for endoscopic resection of early-stage glottic cancer. Head Neck. ePub, 2016
                                                  3. Wang CC et al: Transoral robotic surgery for early glottic carcinoma involving anterior commissure: preliminary reports. Head Neck. 38(6):913-8, 2016
                                                  4. Dziegielewski PT et al: Transoral robotic surgery (TORS) for laryngeal and hypopharyngeal cancers. J Surg Oncol. 112(7):702-6, 2015
                                                  5. Hoffmann C et al: Early glottic cancer involving the anterior commissure treated by transoral laser cordectomy. Laryngoscope. ePub, 2015
                                                  6. Tibbetts KM et al: Role of Advanced Laryngeal Imaging in Glottic Cancer: Early Detection and Evaluation of Glottic Neoplasms. Otolaryngol Clin North Am. 48(4):565-84, 2015
                                                  7. Huang BY et al: Larynx: anatomic imaging for diagnosis and management. Otolaryngol Clin North Am. 45(6):1325-61, 2012
                                                  8. Chen SA et al: Patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. Cancer. 117(22):5047-51, 2011
                                                  9. Lim JY et al: Potential pitfalls and therapeutic implications of pretherapeutic radiologic staging in glottic cancers. Acta Otolaryngol. 131(8):869-75, 2011
                                                  10. Beitler JJ et al: Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. J Clin Oncol. 28(14):2318-22, 2010
                                                  11. Sengupta N et al: Definitive radiotherapy for carcinoma in situ of the true vocal cords. Am J Clin Oncol. 33(1):94-5, 2010
                                                  12. Ansarin M et al: Laser surgery for early glottic cancer: impact of margin status on local control and organ preservation. Arch Otolaryngol Head Neck Surg. 135(4):385-90, 2009
                                                  13. Cagli S et al: The value of routine clinical and radiologic studies in predicting neoplastic invasion of cricoarytenoid units. AJNR Am J Neuroradiol. 30(10):1936-40, 2009
                                                  14. Hafidh M et al: Radiotherapy for T1 and T2 laryngeal cancer: the Dalhousie University experience. J Otolaryngol Head Neck Surg. 38(4):434-9, 2009
                                                  15. Karatzanis AD et al: Comparison among different available surgical approaches in T1 glottic cancer. Laryngoscope. 119(9):1704-8, 2009
                                                  16. Kuribayashi S et al: Utility of sonography for evaluation of clinical T1 and T2 glottic carcinoma. J Ultrasound Med. 28(11):1429-40, 2009
                                                  17. Patel NP et al: Metastatic calcification involving the true vocal cord. Am J Otolaryngol. 30(3):216-8, 2009
                                                  18. Pittore B et al: Thyroarytenoid muscle invasion in T1 glottic carcinoma. Eur Arch Otorhinolaryngol. 266(11):1787-91, 2009
                                                  19. Rödel RM et al: Endoscopic laser surgery of early glottic cancer: involvement of the anterior commissure. Head Neck. 31(5):583-92, 2009
                                                  20. Sachse F et al: Evaluation of treatment results with regard to initial anterior commissure involvement in early glottic carcinoma treated by external partial surgery or transoral laser microresection. Head Neck. 31(4):531-7, 2009
                                                  21. Shvero J et al: T1 glottic carcinoma involving the posterior commissure. Laryngoscope. 119(6):1116-9, 2009
                                                  22. Sjögren EV et al: Outcome of radiotherapy in T1 glottic carcinoma: a population-based study. Eur Arch Otorhinolaryngol. 266(5):735-44, 2009
                                                  23. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                                                  24. Becker M et al: Neoplastic invasion of laryngeal cartilage: reassessment of criteria for diagnosis at MR imaging. Radiology. 249(2):551-9, 2008
                                                  25. Charbonneau N et al: Treatment results of carcinoma in situ of the glottic larynx: 61 patients treated with radiotherapy. J Otolaryngol Head Neck Surg. 37(4):572-6, 2008
                                                  26. Choong NW et al: Recurrent laryngeal nerve palsy on integrated positron emission tomography-computed tomography. J Thorac Oncol. 3(10):1172, 2008
                                                  27. Dornfeld K et al: Posttreatment FDG-PET uptake in the supraglottic and glottic larynx correlates with decreased quality of life after chemoradiotherapy. Int J Radiat Oncol Biol Phys. 71(2):386-92, 2008
                                                  28. Hamzany Y et al: Laryngeal carcinoma in nonsmoking patients. Ann Otol Rhinol Laryngol. 117(8):564-8, 2008
                                                  29. Kourelis K et al: Glottic versus supraglottic tumors: differential molecular profile. Eur Arch Otorhinolaryngol. 265(1):79-84, 2008
                                                  30. Nomiya T et al: Long-term results of radiotherapy for T1a and T1bN0M0 glottic carcinoma. Laryngoscope. 118(8):1417-21, 2008
                                                  31. Roh JL et al: The utility of second-look operation after laser microresection of glottic carcinoma involving the anterior commissure. Laryngoscope. 118(8):1400-4, 2008
                                                  32. Liu JC et al: Squamous cell carcinoma masquerading as a vocal fold papilloma. Ear Nose Throat J. 86(10):594, 2007
                                                  33. Hermans R: Staging of laryngeal and hypopharyngeal cancer: value of imaging studies. Eur Radiol. 16(11):2386-400, 2006
                                                  34. Barthel SW et al: Primary radiation therapy for early glottic cancer. Otolaryngol Head Neck Surg. 124(1):35-9, 2001
                                                  Related Anatomy
                                                  Loading...
                                                  Related Differential Diagnoses
                                                  Loading...
                                                  References
                                                  Tables

                                                  Tables

                                                  KEY FACTS

                                                  • Terminology

                                                    • Imaging

                                                      • Top Differential Diagnoses

                                                        • Pathology

                                                          • Clinical Issues

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Glottic squamous cell carcinoma (G-SCCa)

                                                            • Definitions

                                                              • SCCa arising on mucosal surface of glottic larynx
                                                                • Vocal cord, anterior and posterior commissures

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Nuclear Medicine Findings

                                                                      • Imaging Recommendations

                                                                        • Ultrasonographic Findings

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Staging, Grading, & Classification

                                                                                • Gross Pathologic & Surgical Features

                                                                                  • Microscopic Features

                                                                                    CLINICAL ISSUES

                                                                                    • Presentation

                                                                                      • Demographics

                                                                                        • Natural History & Prognosis

                                                                                          • Treatment

                                                                                            DIAGNOSTIC CHECKLIST

                                                                                            • Consider

                                                                                              • Image Interpretation Pearls

                                                                                                • Reporting Tips

                                                                                                  Selected References

                                                                                                  1. Brady JS et al: Survival Impact of Initial Therapy in Patients with T1-T2 Glottic Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. ePub, 2016
                                                                                                  2. Monnier Y et al: Transthyrohyoid access to the larynx for endoscopic resection of early-stage glottic cancer. Head Neck. ePub, 2016
                                                                                                  3. Wang CC et al: Transoral robotic surgery for early glottic carcinoma involving anterior commissure: preliminary reports. Head Neck. 38(6):913-8, 2016
                                                                                                  4. Dziegielewski PT et al: Transoral robotic surgery (TORS) for laryngeal and hypopharyngeal cancers. J Surg Oncol. 112(7):702-6, 2015
                                                                                                  5. Hoffmann C et al: Early glottic cancer involving the anterior commissure treated by transoral laser cordectomy. Laryngoscope. ePub, 2015
                                                                                                  6. Tibbetts KM et al: Role of Advanced Laryngeal Imaging in Glottic Cancer: Early Detection and Evaluation of Glottic Neoplasms. Otolaryngol Clin North Am. 48(4):565-84, 2015
                                                                                                  7. Huang BY et al: Larynx: anatomic imaging for diagnosis and management. Otolaryngol Clin North Am. 45(6):1325-61, 2012
                                                                                                  8. Chen SA et al: Patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. Cancer. 117(22):5047-51, 2011
                                                                                                  9. Lim JY et al: Potential pitfalls and therapeutic implications of pretherapeutic radiologic staging in glottic cancers. Acta Otolaryngol. 131(8):869-75, 2011
                                                                                                  10. Beitler JJ et al: Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. J Clin Oncol. 28(14):2318-22, 2010
                                                                                                  11. Sengupta N et al: Definitive radiotherapy for carcinoma in situ of the true vocal cords. Am J Clin Oncol. 33(1):94-5, 2010
                                                                                                  12. Ansarin M et al: Laser surgery for early glottic cancer: impact of margin status on local control and organ preservation. Arch Otolaryngol Head Neck Surg. 135(4):385-90, 2009
                                                                                                  13. Cagli S et al: The value of routine clinical and radiologic studies in predicting neoplastic invasion of cricoarytenoid units. AJNR Am J Neuroradiol. 30(10):1936-40, 2009
                                                                                                  14. Hafidh M et al: Radiotherapy for T1 and T2 laryngeal cancer: the Dalhousie University experience. J Otolaryngol Head Neck Surg. 38(4):434-9, 2009
                                                                                                  15. Karatzanis AD et al: Comparison among different available surgical approaches in T1 glottic cancer. Laryngoscope. 119(9):1704-8, 2009
                                                                                                  16. Kuribayashi S et al: Utility of sonography for evaluation of clinical T1 and T2 glottic carcinoma. J Ultrasound Med. 28(11):1429-40, 2009
                                                                                                  17. Patel NP et al: Metastatic calcification involving the true vocal cord. Am J Otolaryngol. 30(3):216-8, 2009
                                                                                                  18. Pittore B et al: Thyroarytenoid muscle invasion in T1 glottic carcinoma. Eur Arch Otorhinolaryngol. 266(11):1787-91, 2009
                                                                                                  19. Rödel RM et al: Endoscopic laser surgery of early glottic cancer: involvement of the anterior commissure. Head Neck. 31(5):583-92, 2009
                                                                                                  20. Sachse F et al: Evaluation of treatment results with regard to initial anterior commissure involvement in early glottic carcinoma treated by external partial surgery or transoral laser microresection. Head Neck. 31(4):531-7, 2009
                                                                                                  21. Shvero J et al: T1 glottic carcinoma involving the posterior commissure. Laryngoscope. 119(6):1116-9, 2009
                                                                                                  22. Sjögren EV et al: Outcome of radiotherapy in T1 glottic carcinoma: a population-based study. Eur Arch Otorhinolaryngol. 266(5):735-44, 2009
                                                                                                  23. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                                                                                                  24. Becker M et al: Neoplastic invasion of laryngeal cartilage: reassessment of criteria for diagnosis at MR imaging. Radiology. 249(2):551-9, 2008
                                                                                                  25. Charbonneau N et al: Treatment results of carcinoma in situ of the glottic larynx: 61 patients treated with radiotherapy. J Otolaryngol Head Neck Surg. 37(4):572-6, 2008
                                                                                                  26. Choong NW et al: Recurrent laryngeal nerve palsy on integrated positron emission tomography-computed tomography. J Thorac Oncol. 3(10):1172, 2008
                                                                                                  27. Dornfeld K et al: Posttreatment FDG-PET uptake in the supraglottic and glottic larynx correlates with decreased quality of life after chemoradiotherapy. Int J Radiat Oncol Biol Phys. 71(2):386-92, 2008
                                                                                                  28. Hamzany Y et al: Laryngeal carcinoma in nonsmoking patients. Ann Otol Rhinol Laryngol. 117(8):564-8, 2008
                                                                                                  29. Kourelis K et al: Glottic versus supraglottic tumors: differential molecular profile. Eur Arch Otorhinolaryngol. 265(1):79-84, 2008
                                                                                                  30. Nomiya T et al: Long-term results of radiotherapy for T1a and T1bN0M0 glottic carcinoma. Laryngoscope. 118(8):1417-21, 2008
                                                                                                  31. Roh JL et al: The utility of second-look operation after laser microresection of glottic carcinoma involving the anterior commissure. Laryngoscope. 118(8):1400-4, 2008
                                                                                                  32. Liu JC et al: Squamous cell carcinoma masquerading as a vocal fold papilloma. Ear Nose Throat J. 86(10):594, 2007
                                                                                                  33. Hermans R: Staging of laryngeal and hypopharyngeal cancer: value of imaging studies. Eur Radiol. 16(11):2386-400, 2006
                                                                                                  34. Barthel SW et al: Primary radiation therapy for early glottic cancer. Otolaryngol Head Neck Surg. 124(1):35-9, 2001
                                                                                                  Contact UsStoreTerms and ConditionsRegistered User AgreementPrivacy PolicyHelp