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KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Gonadal stromal tumors (GST)
Synonyms
- Also called nongerm cell tumors, interstitial cell tumors, or sex cord tumors
Definitions
- Neoplasm arising from nongerm cell elements
- Leydig cell tumor (LCT): Arises from interstitial cells
- Sertoli cell tumor (SCT): Arises from sustentacular cells lining seminiferous tubules
- Granulosa cell tumor (GCT): Rare sex cord tumor
- Gonadoblastoma: Contains both stromal and germ cell elements
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Miliaras D et al: Adult type granulosa cell tumor: a very rare case of sex-cord tumor of the testis with review of the literature. Case Rep Pathol. 2013:932086, 2013
- Cantisani V et al: Contrast-enhanced ultrasonographic (CEUS) and elastosonographic features of a case of testicular Leydig tumor. Ultraschall Med. 33(5):407-9, 2012
- Leonhartsberger N et al: Increased incidence of Leydig cell tumours of the testis in the era of improved imaging techniques. BJU Int. 108(10):1603-7, 2011
- Tallen G et al: High reliability of scrotal ultrasonography in the management of childhood primary testicular neoplasms. Klin Padiatr. 223(3):131-7, 2011
- Zugor V et al: Congenital juvenile granulosa cell tumor of the testis in newborns. Anticancer Res. 30(5):1731-4, 2010
- Sajadi KP et al: Sex cord-gonadal stromal tumor of the rete testis. Adv Urol. PubMed Central PMCID: PMC2612754, 2009
- Peterson C et al: Prenatal diagnosis of juvenile granulosa cell tumor of the testis. J Pediatr Urol. 4(6):472-4, 2008
- Maizlin ZV et al: Leydig cell tumors of the testis: gray scale and color Doppler sonographic appearance. J Ultrasound Med. 23(7):959-64, 2004
- Carmignani L et al: High incidence of benign testicular neoplasms diagnosed by ultrasound. J Urol. 170(5):1783-6, 2003
- Woodward PJ et al: From the archives of the AFIP: tumors and tumorlike lesions of the testis: radiologic-pathologic correlation. Radiographics. 22(1):189-216, 2002
- Ulbright TM et al. Tumors of the testis, adnexa, spermatic cord, and scrotum. In: Atlas of Tumor Pathology. Washington, DC: Armed Forces Institute of Pathology. 1–290, 1999
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Gonadal stromal tumors (GST)
Synonyms
- Also called nongerm cell tumors, interstitial cell tumors, or sex cord tumors
Definitions
- Neoplasm arising from nongerm cell elements
- Leydig cell tumor (LCT): Arises from interstitial cells
- Sertoli cell tumor (SCT): Arises from sustentacular cells lining seminiferous tubules
- Granulosa cell tumor (GCT): Rare sex cord tumor
- Gonadoblastoma: Contains both stromal and germ cell elements
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Miliaras D et al: Adult type granulosa cell tumor: a very rare case of sex-cord tumor of the testis with review of the literature. Case Rep Pathol. 2013:932086, 2013
- Cantisani V et al: Contrast-enhanced ultrasonographic (CEUS) and elastosonographic features of a case of testicular Leydig tumor. Ultraschall Med. 33(5):407-9, 2012
- Leonhartsberger N et al: Increased incidence of Leydig cell tumours of the testis in the era of improved imaging techniques. BJU Int. 108(10):1603-7, 2011
- Tallen G et al: High reliability of scrotal ultrasonography in the management of childhood primary testicular neoplasms. Klin Padiatr. 223(3):131-7, 2011
- Zugor V et al: Congenital juvenile granulosa cell tumor of the testis in newborns. Anticancer Res. 30(5):1731-4, 2010
- Sajadi KP et al: Sex cord-gonadal stromal tumor of the rete testis. Adv Urol. PubMed Central PMCID: PMC2612754, 2009
- Peterson C et al: Prenatal diagnosis of juvenile granulosa cell tumor of the testis. J Pediatr Urol. 4(6):472-4, 2008
- Maizlin ZV et al: Leydig cell tumors of the testis: gray scale and color Doppler sonographic appearance. J Ultrasound Med. 23(7):959-64, 2004
- Carmignani L et al: High incidence of benign testicular neoplasms diagnosed by ultrasound. J Urol. 170(5):1783-6, 2003
- Woodward PJ et al: From the archives of the AFIP: tumors and tumorlike lesions of the testis: radiologic-pathologic correlation. Radiographics. 22(1):189-216, 2002
- Ulbright TM et al. Tumors of the testis, adnexa, spermatic cord, and scrotum. In: Atlas of Tumor Pathology. Washington, DC: Armed Forces Institute of Pathology. 1–290, 1999
