Rare autoimmune disorder requiring immediate diagnosis and treatment to improve clinical outcome
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Reisman S et al: A review of clinical and imaging features of diffuse pulmonary hemorrhage. AJR Am J Roentgenol. 1-10, 2021
Pesce F et al: Glomerulonephritis in AKI: from pathogenesis to therapeutic intervention. Front Med (Lausanne). 7:582272, 2020
Boardman EA et al: Goodpasture's disease with late presentation of renal abnormality and anti-GBM autoantibody. BMJ Case Rep. 2017, 2017
McAdoo SP et al: Anti-glomerular basement membrane disease. Clin J Am Soc Nephrol. 12(7):1162-72, 2017
Fernandes R et al: Goodpasture's syndrome with absence of circulating anti-glomerular basement membrane antibodies: a case report. J Med Case Rep. 10:205, 2016
Hellmark T et al: Diagnosis and classification of Goodpasture's disease (anti-GBM). J Autoimmun. 48-49:108-12, 2014
Lichtenberger JP 3rd et al: Diffuse pulmonary hemorrhage: clues to the diagnosis. Curr Probl Diagn Radiol. 43(3):128-39, 2014
Dammacco F et al: Goodpasture's disease: a report of ten cases and a review of the literature. Autoimmun Rev. 12(11):1101-8, 2013
Hasleton et al: Pulmonary vasculitis and pulmonary hemorrhage syndromes. In Spencer's Pathology of the Lung. 6th ed. Cambridge University Press. 711-66, 2013
Lahmer T et al: Anti-glomerular basement membrane antibody disease: a rare autoimmune disorder affecting the kidney and the lung. Autoimmun Rev. 12(2):169-73, 2012
Chan AL et al: Cutting edge issues in Goodpasture's disease. Clin Rev Allergy Immunol. 41(2):151-62, 2011
Pedchenko V et al: Goodpasture's disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis. Curr Opin Nephrol Hypertens. 20(3):290-6, 2011
Chung MP et al: Imaging of pulmonary vasculitis. Radiology. 255(2):322-41, 2010
Lara AR et al: Diffuse alveolar hemorrhage. Chest. 137(5):1164-71, 2010
Savage CO et al: ABC of arterial and vascular disease: vasculitis. Bmj. 320(7245):1325-8, 2000
Primack S: Pulmonary hemorrhage. In Chiles C et al: Pulmonary and cardiac Imaging. New York: Marcel Dekker. 219-43, 1997
Primack SL et al: Diffuse pulmonary hemorrhage: clinical, pathologic, and imaging features. AJR Am J Roentgenol. 164(2):295-300, 1995
Conlon PJ et al: Antiglomerular basement membrane disease: the long-term pulmonary outcome. Am J Kidney Dis. 23(6):794-6, 1994
Muller NL et al: Diffuse pulmonary hemorrhage. Radiol Clin North Am. 29(5):965-71, 1991
Young KR et al: Pulmonary-renal syndromes. Clin Chest Med. 10(4):655-75, 1989
Donaghy M et al: Cigarette smoking and lung haemorrhage in glomerulonephritis caused by autoantibodies to glomerular basement membrane. Lancet. 2(8364):1390-3, 1983
Rare autoimmune disorder requiring immediate diagnosis and treatment to improve clinical outcome
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Reisman S et al: A review of clinical and imaging features of diffuse pulmonary hemorrhage. AJR Am J Roentgenol. 1-10, 2021
Pesce F et al: Glomerulonephritis in AKI: from pathogenesis to therapeutic intervention. Front Med (Lausanne). 7:582272, 2020
Boardman EA et al: Goodpasture's disease with late presentation of renal abnormality and anti-GBM autoantibody. BMJ Case Rep. 2017, 2017
McAdoo SP et al: Anti-glomerular basement membrane disease. Clin J Am Soc Nephrol. 12(7):1162-72, 2017
Fernandes R et al: Goodpasture's syndrome with absence of circulating anti-glomerular basement membrane antibodies: a case report. J Med Case Rep. 10:205, 2016
Hellmark T et al: Diagnosis and classification of Goodpasture's disease (anti-GBM). J Autoimmun. 48-49:108-12, 2014
Lichtenberger JP 3rd et al: Diffuse pulmonary hemorrhage: clues to the diagnosis. Curr Probl Diagn Radiol. 43(3):128-39, 2014
Dammacco F et al: Goodpasture's disease: a report of ten cases and a review of the literature. Autoimmun Rev. 12(11):1101-8, 2013
Hasleton et al: Pulmonary vasculitis and pulmonary hemorrhage syndromes. In Spencer's Pathology of the Lung. 6th ed. Cambridge University Press. 711-66, 2013
Lahmer T et al: Anti-glomerular basement membrane antibody disease: a rare autoimmune disorder affecting the kidney and the lung. Autoimmun Rev. 12(2):169-73, 2012
Chan AL et al: Cutting edge issues in Goodpasture's disease. Clin Rev Allergy Immunol. 41(2):151-62, 2011
Pedchenko V et al: Goodpasture's disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis. Curr Opin Nephrol Hypertens. 20(3):290-6, 2011
Chung MP et al: Imaging of pulmonary vasculitis. Radiology. 255(2):322-41, 2010
Lara AR et al: Diffuse alveolar hemorrhage. Chest. 137(5):1164-71, 2010
Savage CO et al: ABC of arterial and vascular disease: vasculitis. Bmj. 320(7245):1325-8, 2000
Primack S: Pulmonary hemorrhage. In Chiles C et al: Pulmonary and cardiac Imaging. New York: Marcel Dekker. 219-43, 1997
Primack SL et al: Diffuse pulmonary hemorrhage: clinical, pathologic, and imaging features. AJR Am J Roentgenol. 164(2):295-300, 1995
Conlon PJ et al: Antiglomerular basement membrane disease: the long-term pulmonary outcome. Am J Kidney Dis. 23(6):794-6, 1994
Muller NL et al: Diffuse pulmonary hemorrhage. Radiol Clin North Am. 29(5):965-71, 1991
Young KR et al: Pulmonary-renal syndromes. Clin Chest Med. 10(4):655-75, 1989
Donaghy M et al: Cigarette smoking and lung haemorrhage in glomerulonephritis caused by autoantibodies to glomerular basement membrane. Lancet. 2(8364):1390-3, 1983
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