Disease of allogenic bone marrow transplant (BMT) or stem cell transplant (SCT) recipients
Donor T lymphocytes cause damage to epithelial cells lining recipient target organs
IMAGING
General Features
Radiographic Findings
Fluoroscopic Findings
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Concepcion NDP et al: Imaging assessment of complications from transplantation from pediatric to adult patients: part 2: hematopoietic stem cell transplantation. Radiol Clin North Am. 58(3):569-82, 2020
Yan Y et al: Pulmonary acute graft-versus-host disease and infections after allogeneic hematopoietic stem cell transplantation in pediatric recipients: a comparative study on CT. Transpl Infect Dis. 22(4):e13285, 2020
Weber D et al: Non-invasive diagnosis of acute intestinal graft-versus-host disease by a new scoring system using ultrasound morphology, compound elastography, and contrast-enhanced ultrasound. Bone Marrow Transplant. 54(7):1038-48, 2019
Derlin T et al: Magnetic resonance enterography for assessment of intestinal graft-versus-host disease after allogeneic stem cell transplantation. Eur Radiol. 25(5):1229-37, 2015
Budjan J et al: Assessment of acute intestinal graft versus host disease by abdominal magnetic resonance imaging at 3 Tesla. Eur Radiol. 24(8):1835-44, 2014
Mahgerefteh SY et al: Radiologic imaging and intervention for gastrointestinal and hepatic complications of hematopoietic stem cell transplantation. Radiology. 258(3):660-71, 2011
Spira D et al: Diagnostic imaging in hematology. Gastrointestinal graft-versus-host disease due to donor lymphocyte administration for rising autologous chimerism. Am J Hematol. 86(1):69, 2011
Ferrara JL et al: Graft-versus-host disease. Lancet. 373(9674):1550-61, 2009
Donnelly LF: CT imaging of immunocompromised children with acute abdominal symptoms. AJR Am J Roentgenol. 167(4):909-13, 1996
Donnelly LF et al: Acute graft-versus-host disease in children: abdominal CT findings. Radiology. 199(1):265-8, 1996
Benya EC et al: Abdominal complications after bone marrow transplantation in children: sonographic and CT findings. AJR Am J Roentgenol. 161(5):1023-7, 1993
Day DL et al: Abdominal complications in pediatric bone marrow transplant recipients. Radiographics. 13(5):1101-12, 1993
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Abbreviations
Graft-vs.-host disease (GVHD)
Definitions
Disease of allogenic bone marrow transplant (BMT) or stem cell transplant (SCT) recipients
Donor T lymphocytes cause damage to epithelial cells lining recipient target organs
IMAGING
General Features
Radiographic Findings
Fluoroscopic Findings
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Concepcion NDP et al: Imaging assessment of complications from transplantation from pediatric to adult patients: part 2: hematopoietic stem cell transplantation. Radiol Clin North Am. 58(3):569-82, 2020
Yan Y et al: Pulmonary acute graft-versus-host disease and infections after allogeneic hematopoietic stem cell transplantation in pediatric recipients: a comparative study on CT. Transpl Infect Dis. 22(4):e13285, 2020
Weber D et al: Non-invasive diagnosis of acute intestinal graft-versus-host disease by a new scoring system using ultrasound morphology, compound elastography, and contrast-enhanced ultrasound. Bone Marrow Transplant. 54(7):1038-48, 2019
Derlin T et al: Magnetic resonance enterography for assessment of intestinal graft-versus-host disease after allogeneic stem cell transplantation. Eur Radiol. 25(5):1229-37, 2015
Budjan J et al: Assessment of acute intestinal graft versus host disease by abdominal magnetic resonance imaging at 3 Tesla. Eur Radiol. 24(8):1835-44, 2014
Mahgerefteh SY et al: Radiologic imaging and intervention for gastrointestinal and hepatic complications of hematopoietic stem cell transplantation. Radiology. 258(3):660-71, 2011
Spira D et al: Diagnostic imaging in hematology. Gastrointestinal graft-versus-host disease due to donor lymphocyte administration for rising autologous chimerism. Am J Hematol. 86(1):69, 2011
Ferrara JL et al: Graft-versus-host disease. Lancet. 373(9674):1550-61, 2009
Donnelly LF: CT imaging of immunocompromised children with acute abdominal symptoms. AJR Am J Roentgenol. 167(4):909-13, 1996
Donnelly LF et al: Acute graft-versus-host disease in children: abdominal CT findings. Radiology. 199(1):265-8, 1996
Benya EC et al: Abdominal complications after bone marrow transplantation in children: sonographic and CT findings. AJR Am J Roentgenol. 161(5):1023-7, 1993
Day DL et al: Abdominal complications in pediatric bone marrow transplant recipients. Radiographics. 13(5):1101-12, 1993
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