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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Guillain-Barré syndrome (GBS)
Synonyms
- Acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
- Ascending paralysis
Definitions
- Group of disorders characterized by acute development of weakness & diminished reflexes secondary to inflammatory polyradiculopathy
- Several subtypes exist
- AIDP
- Acute motor axonal neuropathy
- Acute motor sensory axonal neuropathy
- Miller-Fisher syndrome
- Several subtypes exist
- Primarily clinical diagnosis with supporting imaging findings
- Group of disorders characterized by acute development of weakness & diminished reflexes secondary to inflammatory polyradiculopathy
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Chung A et al: Guillain-Barré syndrome. Pediatr Rev. 39(1):53-4, 2018
- Mancera-Páez O et al: Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika: a case report and review of the pathogenic role of multiple arboviral immunity. J Neurol Sci. 395:47-53, 2018
- Principi N et al: Vaccine-preventable diseases, vaccines and Guillain-Barre' syndrome. Vaccine. ePub, 2018
- Bordini BJ et al: Differentiating familial neuropathies from Guillain-Barré syndrome. Pediatr Clin North Am. 64(1):231-52, 2017
- Wijdicks EF et al: Guillain-Barré syndrome. Mayo Clin Proc. 92(3):467-79, 2017
- Fontes CA et al: Magnetic resonance imaging findings in Guillain-Barré syndrome caused by Zika virus infection. Neuroradiology. 58(8):837-8, 2016
- Heikema AP et al: Campylobacter jejuni capsular genotypes are related to Guillain-Barré syndrome. Clin Microbiol Infect. 21(9):852.e1-9, 2015
- Capasso M et al: Involvement of sensory fibres in axonal subtypes of Guillain-Barre syndrome. J Neurol Neurosurg Psychiatry. 82(6):664-70, 2011
- Orlikowski D et al: Guillain-Barré syndrome following primary cytomegalovirus infection: a prospective cohort study. Clin Infect Dis. 52(7):837-44, 2011
- Roodbol J et al: Recognizing Guillain-Barre syndrome in preschool children. Neurology. 76(9):807-10, 2011
- Zuccoli G et al: Redefining the Guillain-Barré spectrum in children: neuroimaging findings of cranial nerve involvement. AJNR Am J Neuroradiol. 32(4):639-42, 2011
- Buzzigoli SB et al: Plasmapheresis treatment in Guillain-Barré syndrome: potential benefit over intravenous immunoglobulin. Anaesth Intensive Care. 38(2):387-9, 2010
- Islam Z et al: Axonal variant of Guillain-Barre syndrome associated with Campylobacter infection in Bangladesh. Neurology. 74(7):581-7, 2010
- Mulkey SB et al: Nerve root enhancement on spinal MRI in pediatric Guillain-Barré syndrome. Pediatr Neurol. 43(4):263-9, 2010
- Vallat JM et al: Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition. Lancet Neurol. 9(4):402-12, 2010
- van Doorn PA et al: IVIG treatment and prognosis in Guillain-Barré syndrome. J Clin Immunol. 30 Suppl 1:S74-8, 2010
- Chang YW et al: Spinal MRI of vincristine neuropathy mimicking Guillain-Barré syndrome. Pediatr Radiol. 33(11):791-3, 2003
- Cheng BC et al: Guillain-Barré syndrome in southern Taiwan: clinical features, prognostic factors and therapeutic outcomes. Eur J Neurol. 10(6):655-62, 2003
- Haber P et al: Influenza vaccination and Guillain Barré syndrome. Clin Immunol. 109(3):359; author reply 360-1, 2003
- Duarte J et al: Hypertrophy of multiple cranial nerves and spinal roots in chronic inflammatory demyelinating neuropathy. J Neurol Neurosurg Psychiatry. 67(5):685-7, 1999
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Guillain-Barré syndrome (GBS)
Synonyms
- Acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
- Ascending paralysis
Definitions
- Group of disorders characterized by acute development of weakness & diminished reflexes secondary to inflammatory polyradiculopathy
- Several subtypes exist
- AIDP
- Acute motor axonal neuropathy
- Acute motor sensory axonal neuropathy
- Miller-Fisher syndrome
- Several subtypes exist
- Primarily clinical diagnosis with supporting imaging findings
- Group of disorders characterized by acute development of weakness & diminished reflexes secondary to inflammatory polyradiculopathy
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Chung A et al: Guillain-Barré syndrome. Pediatr Rev. 39(1):53-4, 2018
- Mancera-Páez O et al: Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika: a case report and review of the pathogenic role of multiple arboviral immunity. J Neurol Sci. 395:47-53, 2018
- Principi N et al: Vaccine-preventable diseases, vaccines and Guillain-Barre' syndrome. Vaccine. ePub, 2018
- Bordini BJ et al: Differentiating familial neuropathies from Guillain-Barré syndrome. Pediatr Clin North Am. 64(1):231-52, 2017
- Wijdicks EF et al: Guillain-Barré syndrome. Mayo Clin Proc. 92(3):467-79, 2017
- Fontes CA et al: Magnetic resonance imaging findings in Guillain-Barré syndrome caused by Zika virus infection. Neuroradiology. 58(8):837-8, 2016
- Heikema AP et al: Campylobacter jejuni capsular genotypes are related to Guillain-Barré syndrome. Clin Microbiol Infect. 21(9):852.e1-9, 2015
- Capasso M et al: Involvement of sensory fibres in axonal subtypes of Guillain-Barre syndrome. J Neurol Neurosurg Psychiatry. 82(6):664-70, 2011
- Orlikowski D et al: Guillain-Barré syndrome following primary cytomegalovirus infection: a prospective cohort study. Clin Infect Dis. 52(7):837-44, 2011
- Roodbol J et al: Recognizing Guillain-Barre syndrome in preschool children. Neurology. 76(9):807-10, 2011
- Zuccoli G et al: Redefining the Guillain-Barré spectrum in children: neuroimaging findings of cranial nerve involvement. AJNR Am J Neuroradiol. 32(4):639-42, 2011
- Buzzigoli SB et al: Plasmapheresis treatment in Guillain-Barré syndrome: potential benefit over intravenous immunoglobulin. Anaesth Intensive Care. 38(2):387-9, 2010
- Islam Z et al: Axonal variant of Guillain-Barre syndrome associated with Campylobacter infection in Bangladesh. Neurology. 74(7):581-7, 2010
- Mulkey SB et al: Nerve root enhancement on spinal MRI in pediatric Guillain-Barré syndrome. Pediatr Neurol. 43(4):263-9, 2010
- Vallat JM et al: Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition. Lancet Neurol. 9(4):402-12, 2010
- van Doorn PA et al: IVIG treatment and prognosis in Guillain-Barré syndrome. J Clin Immunol. 30 Suppl 1:S74-8, 2010
- Chang YW et al: Spinal MRI of vincristine neuropathy mimicking Guillain-Barré syndrome. Pediatr Radiol. 33(11):791-3, 2003
- Cheng BC et al: Guillain-Barré syndrome in southern Taiwan: clinical features, prognostic factors and therapeutic outcomes. Eur J Neurol. 10(6):655-62, 2003
- Haber P et al: Influenza vaccination and Guillain Barré syndrome. Clin Immunol. 109(3):359; author reply 360-1, 2003
- Duarte J et al: Hypertrophy of multiple cranial nerves and spinal roots in chronic inflammatory demyelinating neuropathy. J Neurol Neurosurg Psychiatry. 67(5):685-7, 1999
