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Hard Palate Squamous Cell Carcinoma
Nicholas A. Koontz, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Hard palate squamous cell carcinoma (SCCa)
            • Definitions

              • Oral cavity malignancy arising from mucosa overlying hard palate

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. Givi B et al: Impact of elective neck dissection on the outcome of oral squamous cell carcinomas arising in the maxillary alveolus and hard palate. Head Neck. 38 Suppl 1:E1688-94, 2016
                                              2. Yang X et al: Clinicopathological characteristics and outcome predictors in squamous cell carcinoma of the maxillary gingiva and hard palate. J Oral Maxillofac Surg. 73(7):1429-36, 2015
                                              3. Arya S et al: Oral cavity squamous cell carcinoma: role of pretreatment imaging and its influence on management. Clin Radiol. 69(9):916-30, 2014
                                              4. Aydil U et al: Neoplasms of the hard palate. J Oral Maxillofac Surg. 72(3):619-26, 2014
                                              5. Kato H et al: CT and MR imaging findings of palatal tumors. Eur J Radiol. 83(3):e137-46, 2014
                                              6. Brown JS et al: Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity. Head Neck. Epub ahead of print, 2012
                                              7. Eskander A et al: Outcome predictors in squamous cell carcinoma of the maxillary alveolus and hard palate. Laryngoscope. 123(10):2453-8, 2013
                                              8. Li Q et al: Survival impact of cervical metastasis in squamous cell carcinoma of hard palate. Oral Surg Oral Med Oral Pathol Oral Radiol. 116(1):23-7, 2013
                                              9. Meng FY et al: The determining risk factors for treatment outcomes in patients with squamous cell carcinoma of the hard palate. Ann Surg Oncol. 19(6):2003-10, 2012
                                              10. Sun J et al: Multifocal cutaneous metastases from squamous cell carcinoma of hard palate. Int J Oral Maxillofac Surg. Epub ahead of print, 2011
                                              11. Bagan J et al: Oral cancer: clinical features. Oral Oncol. 46(6):414-7, 2010
                                              12. Jerjes W et al: Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head Neck Oncol. 2:9, 2010
                                              13. Mourouzis C et al: Squamous cell carcinoma of the maxillary gingiva, alveolus, and hard palate: is there a need for elective neck dissection? Br J Oral Maxillofac Surg. 48(5):345-8, 2010
                                              14. Shrime MG et al: The impact of adjuvant radiotherapy on survival in T1-2N1 squamous cell carcinoma of the oral cavity. Arch Otolaryngol Head Neck Surg. 2010 Mar;136(3):225-8. Erratum in: Arch Otolaryngol Head Neck Surg. 136(5):512, 2010
                                              15. Valentini V et al: Management of clinically negative neck in maxillary carcinoma. J Craniofac Surg. 21(3):759-62, 2010
                                              16. Viet CT et al: Understanding oral cancer in the genome era. Head Neck. 32(9):1246-68, 2010
                                              17. Wang TC et al: Risk factors affect the survival outcome of hard palatal and maxillary alveolus squamous cell carcinoma: 10-year review in a tertiary referral center. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 110(1):11-7, 2010
                                              18. Lin HW et al: Survival impact of nodal disease in hard palate and maxillary alveolus cancer. Laryngoscope. 119(2):312-5, 2009
                                              19. Montes DM et al: Oral maxillary squamous cell carcinoma: management of the clinically negative neck. J Oral Maxillofac Surg. 66(4):762-6, 2008
                                              20. Simental AA Jr et al: Cervical metastasis from squamous cell carcinoma of the maxillary alveolus and hard palate. Laryngoscope. 116(9):1682-4, 2006
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Hard palate squamous cell carcinoma (SCCa)
                                                        • Definitions

                                                          • Oral cavity malignancy arising from mucosa overlying hard palate

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. Givi B et al: Impact of elective neck dissection on the outcome of oral squamous cell carcinomas arising in the maxillary alveolus and hard palate. Head Neck. 38 Suppl 1:E1688-94, 2016
                                                                                          2. Yang X et al: Clinicopathological characteristics and outcome predictors in squamous cell carcinoma of the maxillary gingiva and hard palate. J Oral Maxillofac Surg. 73(7):1429-36, 2015
                                                                                          3. Arya S et al: Oral cavity squamous cell carcinoma: role of pretreatment imaging and its influence on management. Clin Radiol. 69(9):916-30, 2014
                                                                                          4. Aydil U et al: Neoplasms of the hard palate. J Oral Maxillofac Surg. 72(3):619-26, 2014
                                                                                          5. Kato H et al: CT and MR imaging findings of palatal tumors. Eur J Radiol. 83(3):e137-46, 2014
                                                                                          6. Brown JS et al: Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity. Head Neck. Epub ahead of print, 2012
                                                                                          7. Eskander A et al: Outcome predictors in squamous cell carcinoma of the maxillary alveolus and hard palate. Laryngoscope. 123(10):2453-8, 2013
                                                                                          8. Li Q et al: Survival impact of cervical metastasis in squamous cell carcinoma of hard palate. Oral Surg Oral Med Oral Pathol Oral Radiol. 116(1):23-7, 2013
                                                                                          9. Meng FY et al: The determining risk factors for treatment outcomes in patients with squamous cell carcinoma of the hard palate. Ann Surg Oncol. 19(6):2003-10, 2012
                                                                                          10. Sun J et al: Multifocal cutaneous metastases from squamous cell carcinoma of hard palate. Int J Oral Maxillofac Surg. Epub ahead of print, 2011
                                                                                          11. Bagan J et al: Oral cancer: clinical features. Oral Oncol. 46(6):414-7, 2010
                                                                                          12. Jerjes W et al: Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head Neck Oncol. 2:9, 2010
                                                                                          13. Mourouzis C et al: Squamous cell carcinoma of the maxillary gingiva, alveolus, and hard palate: is there a need for elective neck dissection? Br J Oral Maxillofac Surg. 48(5):345-8, 2010
                                                                                          14. Shrime MG et al: The impact of adjuvant radiotherapy on survival in T1-2N1 squamous cell carcinoma of the oral cavity. Arch Otolaryngol Head Neck Surg. 2010 Mar;136(3):225-8. Erratum in: Arch Otolaryngol Head Neck Surg. 136(5):512, 2010
                                                                                          15. Valentini V et al: Management of clinically negative neck in maxillary carcinoma. J Craniofac Surg. 21(3):759-62, 2010
                                                                                          16. Viet CT et al: Understanding oral cancer in the genome era. Head Neck. 32(9):1246-68, 2010
                                                                                          17. Wang TC et al: Risk factors affect the survival outcome of hard palatal and maxillary alveolus squamous cell carcinoma: 10-year review in a tertiary referral center. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 110(1):11-7, 2010
                                                                                          18. Lin HW et al: Survival impact of nodal disease in hard palate and maxillary alveolus cancer. Laryngoscope. 119(2):312-5, 2009
                                                                                          19. Montes DM et al: Oral maxillary squamous cell carcinoma: management of the clinically negative neck. J Oral Maxillofac Surg. 66(4):762-6, 2008
                                                                                          20. Simental AA Jr et al: Cervical metastasis from squamous cell carcinoma of the maxillary alveolus and hard palate. Laryngoscope. 116(9):1682-4, 2006