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Hemangioma, Cervical Spine
Cheryl A. Petersilge, MD, MBA
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Common benign venous malformation within vertebrae

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Bouali S et al: Intradural extramedullary capillary hemangioma in the upper cervical spine: first report. World Neurosurg. 92:587.e1-7, 2016
                                              2. Ayhan S et al: Concomitant intramedullary arteriovenous malformation and a vertebral hemangioma of cervical spine discovered by a pathologic fracture during bicycle accident. Eur Spine J. 24(1):187-92, 2015
                                              3. Sade R et al: Cervical hemangioma with neurologic deficit. Spine J. 15(8):1888-9, 2015
                                              4. Miller D et al: Osteolytic mass bridging two cervical vertebrae: Unusual presentation of a vertebral body hemangioma. Radiol Case Rep. 9(4):927, 2014
                                              5. Hurley MC et al: Preoperative Onyx embolization of aggressive vertebral hemangiomas. AJNR Am J Neuroradiol. 29(6):1095-7, 2008
                                              6. Bandiera S et al: Symptomatic vertebral hemangioma: the treatment of 23 cases and a review of the literature. Chir Organi Mov. 87(1):1-15, 2002
                                              7. Gabal AM: Percutaneous technique for sclerotherapy of vertebral hemangioma compressing spinal cord. Cardiovasc Intervent Radiol. 25(6):494-500, 2002
                                              8. Murugan L et al: Management of symptomatic vertebral hemangiomas: review of 13 patients. Neurol India. 50(3): 300-5, 2002
                                              9. Bas T et al: Efficacy and safety of ethanol injections in 18 cases of vertebral hemangioma: a mean follow-up of 2 years. Spine. 26(14): 1577-82, 2001
                                              10. Baudrez V et al: Benign vertebral hemangioma: MR-histological correlation. Skeletal Radiol. 30(8): 442-6, 2001
                                              11. Miszczyk L et al: The efficacy of radiotherapy for vertebral hemangiomas. Neoplasma. 48(1):82-4, 2001
                                              12. Cross JJ et al: Imaging of compressive vertebral haemangiomas. Eur Radiol. 10(6):997-1002, 2000
                                              13. Doppman JL et al: Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of ethanol. Radiology. 214(2): 341-8, 2000
                                              14. Lee S et al: Extraosseous extension of vertebral hemangioma, a rare cause of spinal cord compression. Spine. 24(20): 2111-4, 1999
                                              15. Pastushyn AI et al: Vertebral hemangiomas: diagnosis, management, natural history and clinicopathological correlates in 86 patients. Surg Neurol. 50(6): 535-47, 1998
                                              16. Griffith JF et al: Clinics in diagnostic imaging (25). Aggressive vertebral haemangioma. Singapore Med J. 38(5): 226-30, 1997
                                              17. Jayakumar PN et al: Symptomatic vertebral haemangioma: endovascular treatment of 12 patients. Spinal Cord. 35(9): 624-8, 1997
                                              18. Sakata K et al: Radiotherapy of vertebral hemangiomas. Acta Oncol. 36(7):719-24, 1997
                                              19. Ide C et al: Vertebral haemangiomas with spinal cord compression: the place of preoperative percutaneous vertebroplasty with methyl methacrylate. Neuroradiology. 38(6): 585-9, 1996
                                              20. Guedea F et al: The role of radiation therapy in vertebral hemangiomas without neurological signs. Int Orthop. 18(2): 77-9, 1994
                                              21. Fox MW et al: The natural history and management of symptomatic and asymptomatic vertebral hemangiomas. J Neurosurg. 78(1): 36-45, 1993
                                              22. Laredo JD et al: Vertebral hemangiomas: fat content as a sign of aggressiveness. Radiology. 177(2):467-72, 1990
                                              23. Nguyen JP et al: Vertebral hemangiomas presenting with neurologic symptoms. Surg Neurol. 27(4):391-7, 1987
                                              24. Nicola N et al: Vertebral hemangioma: retrograde embolization-stabilization with methyl methacrylate. Surg Neurol. 27(5):481-6, 1987
                                              25. Ross JS et al: Vertebral hemangiomas: MR imaging. Radiology. 165(1):165-9, 1987
                                              26. Laredo JD et al: Vertebral hemangiomas: radiologic evaluation. Radiology. 161(1):183-9, 1986
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Common benign venous malformation within vertebrae

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Angiographic Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Bouali S et al: Intradural extramedullary capillary hemangioma in the upper cervical spine: first report. World Neurosurg. 92:587.e1-7, 2016
                                                                                          2. Ayhan S et al: Concomitant intramedullary arteriovenous malformation and a vertebral hemangioma of cervical spine discovered by a pathologic fracture during bicycle accident. Eur Spine J. 24(1):187-92, 2015
                                                                                          3. Sade R et al: Cervical hemangioma with neurologic deficit. Spine J. 15(8):1888-9, 2015
                                                                                          4. Miller D et al: Osteolytic mass bridging two cervical vertebrae: Unusual presentation of a vertebral body hemangioma. Radiol Case Rep. 9(4):927, 2014
                                                                                          5. Hurley MC et al: Preoperative Onyx embolization of aggressive vertebral hemangiomas. AJNR Am J Neuroradiol. 29(6):1095-7, 2008
                                                                                          6. Bandiera S et al: Symptomatic vertebral hemangioma: the treatment of 23 cases and a review of the literature. Chir Organi Mov. 87(1):1-15, 2002
                                                                                          7. Gabal AM: Percutaneous technique for sclerotherapy of vertebral hemangioma compressing spinal cord. Cardiovasc Intervent Radiol. 25(6):494-500, 2002
                                                                                          8. Murugan L et al: Management of symptomatic vertebral hemangiomas: review of 13 patients. Neurol India. 50(3): 300-5, 2002
                                                                                          9. Bas T et al: Efficacy and safety of ethanol injections in 18 cases of vertebral hemangioma: a mean follow-up of 2 years. Spine. 26(14): 1577-82, 2001
                                                                                          10. Baudrez V et al: Benign vertebral hemangioma: MR-histological correlation. Skeletal Radiol. 30(8): 442-6, 2001
                                                                                          11. Miszczyk L et al: The efficacy of radiotherapy for vertebral hemangiomas. Neoplasma. 48(1):82-4, 2001
                                                                                          12. Cross JJ et al: Imaging of compressive vertebral haemangiomas. Eur Radiol. 10(6):997-1002, 2000
                                                                                          13. Doppman JL et al: Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of ethanol. Radiology. 214(2): 341-8, 2000
                                                                                          14. Lee S et al: Extraosseous extension of vertebral hemangioma, a rare cause of spinal cord compression. Spine. 24(20): 2111-4, 1999
                                                                                          15. Pastushyn AI et al: Vertebral hemangiomas: diagnosis, management, natural history and clinicopathological correlates in 86 patients. Surg Neurol. 50(6): 535-47, 1998
                                                                                          16. Griffith JF et al: Clinics in diagnostic imaging (25). Aggressive vertebral haemangioma. Singapore Med J. 38(5): 226-30, 1997
                                                                                          17. Jayakumar PN et al: Symptomatic vertebral haemangioma: endovascular treatment of 12 patients. Spinal Cord. 35(9): 624-8, 1997
                                                                                          18. Sakata K et al: Radiotherapy of vertebral hemangiomas. Acta Oncol. 36(7):719-24, 1997
                                                                                          19. Ide C et al: Vertebral haemangiomas with spinal cord compression: the place of preoperative percutaneous vertebroplasty with methyl methacrylate. Neuroradiology. 38(6): 585-9, 1996
                                                                                          20. Guedea F et al: The role of radiation therapy in vertebral hemangiomas without neurological signs. Int Orthop. 18(2): 77-9, 1994
                                                                                          21. Fox MW et al: The natural history and management of symptomatic and asymptomatic vertebral hemangiomas. J Neurosurg. 78(1): 36-45, 1993
                                                                                          22. Laredo JD et al: Vertebral hemangiomas: fat content as a sign of aggressiveness. Radiology. 177(2):467-72, 1990
                                                                                          23. Nguyen JP et al: Vertebral hemangiomas presenting with neurologic symptoms. Surg Neurol. 27(4):391-7, 1987
                                                                                          24. Nicola N et al: Vertebral hemangioma: retrograde embolization-stabilization with methyl methacrylate. Surg Neurol. 27(5):481-6, 1987
                                                                                          25. Ross JS et al: Vertebral hemangiomas: MR imaging. Radiology. 165(1):165-9, 1987
                                                                                          26. Laredo JD et al: Vertebral hemangiomas: radiologic evaluation. Radiology. 161(1):183-9, 1986