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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Arthritis associated with hemochromatosis
- Hemochromatosis: progressive increase in total body iron stores with abnormal iron deposition in multiple organs
- Arthritis associated with hemochromatosis
IMAGING
General Features
Radiographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Scullion S et al: Radiologic imaging of metabolic and endocrine disorders as they affect the hand and wrist. Semin Musculoskelet Radiol. 25(2):246-59, 2021
- Wijarnpreecha K et al: Hereditary hemochromatosis and risk of joint replacement surgery: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol. 33(1):96-101, 2021
- Nguyen CD et al: Bone and joint complications in patients with hereditary hemochromatosis: a cross-sectional study of 93 patients. Ther Adv Musculoskelet Dis. 12:1759720X20939405, 2020
- Elstob A et al: MRI ankle and subtalar characteristics in haemochromatosis arthropathy: a case-control study. Clin Radiol. 73(3):323.e1-8, 2018
- Richardson A et al: Haemochromatosis: unexplained metacarpophalangeal or ankle arthropathy should prompt diagnostic tests: findings from two UK observational cohort studies. Scand J Rheumatol. 46(1):69-74, 2017
- Ekanayake D et al: Recent advances in hemochromatosis: a 2015 update: a summary of proceedings of the 2014 conference held under the auspices of Hemochromatosis Australia. Hepatol Int. 9(2):174-82, 2015
- Husar-Memmer E et al: HFE-related hemochromatosis: an update for the rheumatologist. Curr Rheumatol Rep. 16(1):393, 2014
- Pascart T et al: Treatment of nongout joint deposition diseases: an update. Arthritis. 2014:375202, 2014
- Dallos T et al: Idiopathic hand osteoarthritis vs haemochromatosis arthropathy--a clinical, functional and radiographic study. Rheumatology (Oxford). 52(5):910-5, 2013
- Frenzen K et al: Erosive and inflammatory joint changes in hereditary hemochromatosis arthropathy detected by low-field magnetic resonance imaging. Rheumatol Int. 33(8):2061-7, 2013
- Duval H et al: Hip involvement in hereditary hemochromatosis: a clinical-pathologic study. Joint Bone Spine. 76(4):412-5, 2009
- Valenti L et al: The hand arthropathy of hereditary hemochromatosis is strongly associated with iron overload. J Rheumatol. 35(1):153-8, 2008
- Zafar S et al: Atypical arthritis due to combined hereditary hemochromatosis and active hepatitis C. J Clin Rheumatol. 14(1):21-3, 2008
- Davies MB et al: Ankle arthropathy of hemochromatosis: a case series and review of the literature. Foot Ankle Int. 27(11):902-6, 2006
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
- Arthritis associated with hemochromatosis
- Hemochromatosis: progressive increase in total body iron stores with abnormal iron deposition in multiple organs
- Arthritis associated with hemochromatosis
IMAGING
General Features
Radiographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Scullion S et al: Radiologic imaging of metabolic and endocrine disorders as they affect the hand and wrist. Semin Musculoskelet Radiol. 25(2):246-59, 2021
- Wijarnpreecha K et al: Hereditary hemochromatosis and risk of joint replacement surgery: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol. 33(1):96-101, 2021
- Nguyen CD et al: Bone and joint complications in patients with hereditary hemochromatosis: a cross-sectional study of 93 patients. Ther Adv Musculoskelet Dis. 12:1759720X20939405, 2020
- Elstob A et al: MRI ankle and subtalar characteristics in haemochromatosis arthropathy: a case-control study. Clin Radiol. 73(3):323.e1-8, 2018
- Richardson A et al: Haemochromatosis: unexplained metacarpophalangeal or ankle arthropathy should prompt diagnostic tests: findings from two UK observational cohort studies. Scand J Rheumatol. 46(1):69-74, 2017
- Ekanayake D et al: Recent advances in hemochromatosis: a 2015 update: a summary of proceedings of the 2014 conference held under the auspices of Hemochromatosis Australia. Hepatol Int. 9(2):174-82, 2015
- Husar-Memmer E et al: HFE-related hemochromatosis: an update for the rheumatologist. Curr Rheumatol Rep. 16(1):393, 2014
- Pascart T et al: Treatment of nongout joint deposition diseases: an update. Arthritis. 2014:375202, 2014
- Dallos T et al: Idiopathic hand osteoarthritis vs haemochromatosis arthropathy--a clinical, functional and radiographic study. Rheumatology (Oxford). 52(5):910-5, 2013
- Frenzen K et al: Erosive and inflammatory joint changes in hereditary hemochromatosis arthropathy detected by low-field magnetic resonance imaging. Rheumatol Int. 33(8):2061-7, 2013
- Duval H et al: Hip involvement in hereditary hemochromatosis: a clinical-pathologic study. Joint Bone Spine. 76(4):412-5, 2009
- Valenti L et al: The hand arthropathy of hereditary hemochromatosis is strongly associated with iron overload. J Rheumatol. 35(1):153-8, 2008
- Zafar S et al: Atypical arthritis due to combined hereditary hemochromatosis and active hepatitis C. J Clin Rheumatol. 14(1):21-3, 2008
- Davies MB et al: Ankle arthropathy of hemochromatosis: a case series and review of the literature. Foot Ankle Int. 27(11):902-6, 2006
